Results 91 to 100 of about 17,973 (254)

Connexin 36 expression regulates neuronal differentiation from neural progenitor cells. [PDF]

open access: yesPLoS ONE, 2011
Gap junction communication has been shown in glial and neuronal cells and it is thought they mediate inter- and intra-cellular communication. Connexin 36 (Cx36) is expressed extensively in the developing brain, with levels peaking at P14 after which its ...
Elizabeth M Hartfield   +5 more
doaj   +1 more source

The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]

open access: yes, 2012
Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Gelain F.   +9 more
core   +1 more source

Adult-Brain-Derived Neural Stem Cells Grafting into a Vein Bridge Increases Postlesional Recovery and Regeneration in a Peripheral Nerve of Adult Pig

open access: yesStem Cells International, 2012
We attempted transplantation of adult neural stem cells (ANSCs) inside an autologous venous graft following surgical transsection of nervis cruralis with 30 mm long gap in adult pig.
Olivier Liard   +8 more
doaj   +1 more source

Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells

open access: yesFrontiers in Cellular Neuroscience, 2015
The postnatal subventricular zone lining the walls of the lateral ventricles contains neural progenitor cells (NPCs) that generate new olfactory bulb interneurons.
Rocío eTalaverón   +5 more
doaj   +1 more source

The Atypical Cell Cycle Regulator Spy1 Suppresses Differentiation of the Neuroblastoma Stem Cell Population [PDF]

open access: yes, 2014
Neuroblastoma is an aggressive pediatric cancer originating embryonically from the neural crest. The heterogeneity of the disease, as most solid tumors, complicates diagnosis and treatment.
Lubanska, Dorota, Porter, Lisa A.
core   +3 more sources

Prolactin Receptor Deficiency Promotes Hypomyelination in White Matter Tracts During Postnatal Central Nervous System Maturation in Mice

open access: yesGlia, Volume 74, Issue 2, February 2026.
Prolactin action is essential for proper myelination of white matter tracts during neonatal and prepubertal stages in mice. Lack of prolactin receptor (Prlr−/−) signaling leads to hypomyelination and impaired locomotor function. ABSTRACT A large wave of myelination in the central nervous system (CNS) of mammals occurs during postnatal development ...
Ana L. Ocampo‐Ruiz   +12 more
wiley   +1 more source

Neurosphere-Free Transdifferentiation of Rat Bone Marrow Stromal Stem Cells Into Retinal Cells and Retinal Pigment Epithelium

open access: yesBasic and Clinical Neuroscience, 2021
Introduction: Neurosphere-free transdifferentiation of bone marrow stem cells into Retinal Pigment Epithelium (RPE) and Retinal Cells (RCs) in vitro could offer an exceptional opportunity to study cell replacement in degenerative eye diseases.
Hamid AboutalebKadkhodaeian   +2 more
doaj  

The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells [PDF]

open access: yes, 2007
Doublecortin (DCX) has recently been promulgated as a selective marker of cells committed to the neuronal lineage in both the developing and the adult brain.
Adams, D. J.   +3 more
core   +1 more source

Magnetic Bioprinting and Actuation of Stretchable Muscle Tissue

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 3, 19 January 2026.
Human and murine myoblasts labeled with iron oxide nanoparticles are magnetically bioprinted into wrench‐shaped tissues, which are then anchored between two magnetic needles. Mechanical stretching of these tissues enhances both their maturation and functional performance. Abstract Engineering tissues with precise, long‐lasting shapes and the capability
Noam Demri   +6 more
wiley   +1 more source

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang   +16 more
wiley   +1 more source

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