Results 101 to 110 of about 17,973 (254)
Isolation and Expansion of Neurospheres from Postnatal (P1−3) Mouse Neurogenic Niches [PDF]
Rita Soares +7 more
openalex +1 more source
A novel three-dimensional system to study interactions between endothelial cells and neural cells of the developing central nervous system [PDF]
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Milner, Richard
core +2 more sources
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park +19 more
wiley +1 more source
Astrocytes influence medulloblastoma phenotypes and CD133 surface expression.
The medulloblastoma (MB) microenvironment is diverse, and cell-cell interactions within this milieu is of prime importance. Astrocytes, a major component of the microenvironment, have been shown to impact primary tumor cell phenotypes and metastasis ...
Emily Gronseth +7 more
doaj +1 more source
Schimke immuno-osseous dysplasia (OMIM 242900) is an uncommon autosomal-recessive multisystem disease caused by mutations in SMARCAL1 (swi/snf-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a-like 1), a gene encoding a ...
Armstrong, D.L. +20 more
core +1 more source
Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells [PDF]
The final published version can be found here: http://dx.doi.org/10.1073/pnas ...
Anna Karlsson +18 more
core +1 more source
This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang +13 more
wiley +1 more source
A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses [PDF]
Background. Glioblastoma (GBM) is the most common primary brain tumor, with dismal prognosis. The failure of drug–radiation combinations with promising preclinical data to translate into effective clinical treatments may relate to the use of simplified
Chalmers, Anthony +4 more
core +2 more sources
Unveiling the Genetic Association Between Hemoglobin Concentration and Amyotrophic Lateral Sclerosis
This study identified a causal relationship between genetically predicted hemoglobin (Hb) concentration and amyotrophic lateral sclerosis (ALS) through Mendelian randomization (MR), and integrated RNA‐seq and RT‐qPCR analyses to highlight BACH1, FLVCR1, and TRIM58 as potential genes involved in this association.
Hongmei Luo +4 more
wiley +1 more source
Using Primary Neurosphere Cultures to Study Primary Cilia
The primary cilium is fundamentally important for the proliferation of neural stem/progenitor cells and for neuronal differentiation during embryonic, postnatal, and adult life. In addition, most differentiated neurons possess primary cilia that house signaling receptors, such as G-protein-coupled receptors, and signaling molecules, such as adenylyl ...
Issei S, Shimada +3 more
openaire +3 more sources

