Results 101 to 110 of about 17,973 (254)

Isolation and Expansion of Neurospheres from Postnatal (P1−3) Mouse Neurogenic Niches [PDF]

open access: bronze, 2020
Rita Soares   +7 more
openalex   +1 more source

A novel three-dimensional system to study interactions between endothelial cells and neural cells of the developing central nervous system [PDF]

open access: yes, 2011
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Milner, Richard
core   +2 more sources

Mechanical Environment Afforded by Engineered Hydrogel Critically Regulates Survival of Neural Stem Cells Transplanted in the Injured Spinal Cord via Piezo1‐Mediated Mechanotransduction

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
Neural stem cell transplantation shows promise for spinal cord repair, but poor graft survival limits therapeutic efficacy. This study demonstrates that increasing hydrogel stiffness from 10% to 16% concentration significantly enhances transplanted neural stem cell survival through Piezo1‐mediated mechanotransduction, revealing mechanical properties as
Hee Hwan Park   +19 more
wiley   +1 more source

Astrocytes influence medulloblastoma phenotypes and CD133 surface expression.

open access: yesPLoS ONE, 2020
The medulloblastoma (MB) microenvironment is diverse, and cell-cell interactions within this milieu is of prime importance. Astrocytes, a major component of the microenvironment, have been shown to impact primary tumor cell phenotypes and metastasis ...
Emily Gronseth   +7 more
doaj   +1 more source

Neurologic phenotype of Schimke immuno-osseous dysplasia and neurodevelopmental expression of SMARCAL1

open access: yes, 2008
Schimke immuno-osseous dysplasia (OMIM 242900) is an uncommon autosomal-recessive multisystem disease caused by mutations in SMARCAL1 (swi/snf-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a-like 1), a gene encoding a ...
Armstrong, D.L.   +20 more
core   +1 more source

Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells [PDF]

open access: yes, 2015
The final published version can be found here: http://dx.doi.org/10.1073/pnas ...
Anna Karlsson   +18 more
core   +1 more source

Integrated ERK‐PKA‐YAP/TAZ‐SHH Signaling Orchestrates Cortical Radial Glia Identity and Lineage Diversification

open access: yesAdvanced Science, Volume 13, Issue 5, 27 January 2026.
This study shows that ERK/PKA upregulation in mammalian cortical radial glia (RGs) sustains neurogenesis and suppresses gliogenesis. YAP/TAZ activation promotes ependymal cell formation, while enhanced SHH‐SMO signaling induces astrocyte, oligodendrocytes, and olfactory bulb interneuron generation.
Zhuangzhi Zhang   +13 more
wiley   +1 more source

A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses [PDF]

open access: yes, 2016
Background. Glioblastoma (GBM) is the most common primary brain tumor, with dismal prognosis. The failure of drug–radiation combinations with promising preclinical data to translate into effective clinical treatments may relate to the use of simplified
Chalmers, Anthony   +4 more
core   +2 more sources

Unveiling the Genetic Association Between Hemoglobin Concentration and Amyotrophic Lateral Sclerosis

open access: yesBrain and Behavior, Volume 16, Issue 1, January 2026.
This study identified a causal relationship between genetically predicted hemoglobin (Hb) concentration and amyotrophic lateral sclerosis (ALS) through Mendelian randomization (MR), and integrated RNA‐seq and RT‐qPCR analyses to highlight BACH1, FLVCR1, and TRIM58 as potential genes involved in this association.
Hongmei Luo   +4 more
wiley   +1 more source

Using Primary Neurosphere Cultures to Study Primary Cilia

open access: yesJournal of Visualized Experiments, 2017
The primary cilium is fundamentally important for the proliferation of neural stem/progenitor cells and for neuronal differentiation during embryonic, postnatal, and adult life. In addition, most differentiated neurons possess primary cilia that house signaling receptors, such as G-protein-coupled receptors, and signaling molecules, such as adenylyl ...
Issei S, Shimada   +3 more
openaire   +3 more sources

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