Results 111 to 120 of about 22,415 (298)

Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning

open access: yesAdvanced NanoBiomed Research, EarlyView.
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang   +7 more
wiley   +1 more source

Norepinephrine directly activates adult hippocampal precursors via beta(3)-adrenergic receptors [PDF]

open access: yes, 2010
Adult hippocampal neurogenesis is a critical form of cellular plasticity that is greatly influenced by neural activity. Among the neurotransmitters that are widely implicated in regulating this process are serotonin and norepinephrine, levels of which ...
Bartlett, Perry F.   +6 more
core   +2 more sources

Adult-Brain-Derived Neural Stem Cells Grafting into a Vein Bridge Increases Postlesional Recovery and Regeneration in a Peripheral Nerve of Adult Pig

open access: yesStem Cells International, 2012
We attempted transplantation of adult neural stem cells (ANSCs) inside an autologous venous graft following surgical transsection of nervis cruralis with 30 mm long gap in adult pig.
Olivier Liard   +8 more
doaj   +1 more source

Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells

open access: yesFrontiers in Cellular Neuroscience, 2015
The postnatal subventricular zone lining the walls of the lateral ventricles contains neural progenitor cells (NPCs) that generate new olfactory bulb interneurons.
Rocío eTalaverón   +5 more
doaj   +1 more source

Connexin 36 expression regulates neuronal differentiation from neural progenitor cells. [PDF]

open access: yesPLoS ONE, 2011
Gap junction communication has been shown in glial and neuronal cells and it is thought they mediate inter- and intra-cellular communication. Connexin 36 (Cx36) is expressed extensively in the developing brain, with levels peaking at P14 after which its ...
Elizabeth M Hartfield   +5 more
doaj   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

open access: yesNeuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

A novel fluorescent reporter CDy1 enriches for neural stem cells derived from the murine brain [PDF]

open access: yes, 2013
Neurogenesis occurs continuously in two brain regions of adult mammals, underpinned by a pool of resident neural stem cells (NSCs) that can differentiate into all neural cell types.
Bartlett, Perry F.   +3 more
core   +1 more source

Neurosphere-Free Transdifferentiation of Rat Bone Marrow Stromal Stem Cells Into Retinal Cells and Retinal Pigment Epithelium

open access: yesBasic and Clinical Neuroscience, 2021
Introduction: Neurosphere-free transdifferentiation of bone marrow stem cells into Retinal Pigment Epithelium (RPE) and Retinal Cells (RCs) in vitro could offer an exceptional opportunity to study cell replacement in degenerative eye diseases.
Hamid AboutalebKadkhodaeian   +2 more
doaj  

ODC‐Driven Polyamines Synthesis Sustains the Self‐Renewal of Glioblastoma Stem Cells and Drives Tumor Aggressiveness

open access: yesCancer Science, EarlyView.
Our findings delineate a novel regulatory network that integrates metabolic and GSCs self‐renewal in GBM. By integrating genetic ODC ablation with multiomic profiling, we redefine polyamine metabolism as a linchpin of GSCs self‐renewal, a dependency exploitable through precision gene editing.
Xue‐Chen Wei   +7 more
wiley   +1 more source

The effect of neurosphere culture conditions on the cellular metabolism of glioma cells.

open access: yesFolia Neuropathologica, 2015
Malignant gliomas, with an average survival time of 16-19 months after initial diagnosis, account for one of the most lethal tumours overall. Current standards in patient care provide only unsatisfying strategies in diagnostic and treatment for high ...
U. Kahlert   +9 more
semanticscholar   +1 more source

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