Results 111 to 120 of about 17,973 (254)
Improving treatment of glioblastoma: new insights in targeting cancer stem cells effectively [PDF]
, 2015 Glioblastoma is the most common primary malignant brain tumour in the adult population. Despite multimodality treatment with surgery, radiotherapy and chemotherapy, outcomes are very poor, with less than 15% of patients alive after two years ...
Mannino, Mariella
core
Long-lasting anxiolytic effect of neural precursor cells freshly prepared but not neurosphere-derived cell transplantation in newborn rats [PDF]
, 2014 Background: the GABAergic system plays an important role in modulating levels of anxiety. When transplanted into the brain, precursor cells from the medial ganglionic eminence (MGE) have the ability to differentiate into GABAergic interneurons and modify
Barnabe, Gabriela Filoso +7 more
core +4 more sources
Human Spinal Cord GABAergic Neural Progenitor Cell
Cell Proliferation, EarlyView.
Jia Xu +23 more
wiley +1 more source
Glia, Volume 74, Issue 1, January 2026.Established a C9ORF72 ALS microglia and motor neuron coculture model. Identified an altered inflammatory signature in C9ORF72 ALS microglia. Single‐cell RNA sequencing detected the removal of an LPS responsive microglia subpopulation. ABSTRACT Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disorder involving multiple cell types in ...
Yujing Gao +9 more
wiley +1 more source
Isolating Synaptic Vesicles from Neurospheres for Proteomics
This chapter presents an optimized method for isolating synaptic vesicles (SVs) from neurospheres derived from human induced pluripotent stem cells (hiPSCs). The protocol begins with neurosphere cultivation to achieve mature neurons, which is essential for the functional studies of neuronal activity. Following this, neurosphere-derived synaptosomes are
Brandão-Teles, Caroline +10 more
openaire +5 more sources
Biomimetic microelectronics for regenerative neuronal cuff implants [PDF]
, 2015 Smart biomimetics, a unique class of devices combining the mechanical adaptivity of soft actuators with the imperceptibility of microelectronics, is introduced.
Baunack, Stefan +9 more
core +1 more source
Lifestyle and Behavioural Intervention Therapy for Enhanced Hippocampal Neuroplasticity
Lifestyle Medicine, Volume 7, Issue 1, January 2026.ABSTRACT Background The neurogenic and neuroplastic capability of the brain plays a crucial role in mitigating responses to internal and external environmental stimuli. However, this process is inhibited in obesity, neurodegenerative and psychological disorders, the prevalence of which has increased on a global scale.
Ebrahim Samodien +4 more
wiley +1 more source
Perlecan is required for FGF-2 signaling in the neural stem cell niche
Stem Cell Research, 2014 In the adult subventricular zone (neurogenic niche), neural stem cells double-positive for two markers of subsets of neural stem cells in the adult central nervous system, glial fibrillary acidic protein and CD133, lie in proximity to fractones and to ...
Aurelien Kerever +9 more
doaj +1 more source
Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut [PDF]
, 2004 Enteric neural crest cells (NCCs) migrate and colonize the entire gut and proliferate and differentiate into neurons and glia of the enteric nervous system in vertebrate embryos.
Fu, M +4 more
core +1 more source
Neurons in a Dish: A Review of In Vitro Cell Models for Studying Neurogenesis
Journal of Neurochemistry, Volume 170, Issue 1, January 2026.Different in vitro cell models are valuable to study the different steps of neurogenesis, from the proliferation of neural stem and progenitor cells to the maturation of neurons. Pluripotent stem cells (including embryonic stem cells and induced pluripotent stem cells), immortalized human neuroblastoma cell lines (SH‐SY5Y, IMR‐32), and primary brain ...
Mariana Vassal +3 more
wiley +1 more source