Results 111 to 120 of about 22,415 (298)
Tuning Cellular Perception in Pluripotent Stem Cells through Topography, Stiffness, and Patterning
Micro‐ and nanotopographical cues, substrate stiffness, and mechanical patterning synergistically direct pluripotent stem cell fate and function by tuning cellular perception at the biointerface. Pluripotent stem cells (PSCs), comprised of embryonic stem cells and induced PSCs, hold tremendous therapeutic potential.
Yuan Jiang+7 more
wiley +1 more source
Norepinephrine directly activates adult hippocampal precursors via beta(3)-adrenergic receptors [PDF]
Adult hippocampal neurogenesis is a critical form of cellular plasticity that is greatly influenced by neural activity. Among the neurotransmitters that are widely implicated in regulating this process are serotonin and norepinephrine, levels of which ...
Bartlett, Perry F.+6 more
core +2 more sources
We attempted transplantation of adult neural stem cells (ANSCs) inside an autologous venous graft following surgical transsection of nervis cruralis with 30 mm long gap in adult pig.
Olivier Liard+8 more
doaj +1 more source
The postnatal subventricular zone lining the walls of the lateral ventricles contains neural progenitor cells (NPCs) that generate new olfactory bulb interneurons.
Rocío eTalaverón+5 more
doaj +1 more source
Connexin 36 expression regulates neuronal differentiation from neural progenitor cells. [PDF]
Gap junction communication has been shown in glial and neuronal cells and it is thought they mediate inter- and intra-cellular communication. Connexin 36 (Cx36) is expressed extensively in the developing brain, with levels peaking at P14 after which its ...
Elizabeth M Hartfield+5 more
doaj +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
A novel fluorescent reporter CDy1 enriches for neural stem cells derived from the murine brain [PDF]
Neurogenesis occurs continuously in two brain regions of adult mammals, underpinned by a pool of resident neural stem cells (NSCs) that can differentiate into all neural cell types.
Bartlett, Perry F.+3 more
core +1 more source
Introduction: Neurosphere-free transdifferentiation of bone marrow stem cells into Retinal Pigment Epithelium (RPE) and Retinal Cells (RCs) in vitro could offer an exceptional opportunity to study cell replacement in degenerative eye diseases.
Hamid AboutalebKadkhodaeian+2 more
doaj
Our findings delineate a novel regulatory network that integrates metabolic and GSCs self‐renewal in GBM. By integrating genetic ODC ablation with multiomic profiling, we redefine polyamine metabolism as a linchpin of GSCs self‐renewal, a dependency exploitable through precision gene editing.
Xue‐Chen Wei+7 more
wiley +1 more source
The effect of neurosphere culture conditions on the cellular metabolism of glioma cells.
Malignant gliomas, with an average survival time of 16-19 months after initial diagnosis, account for one of the most lethal tumours overall. Current standards in patient care provide only unsatisfying strategies in diagnostic and treatment for high ...
U. Kahlert+9 more
semanticscholar +1 more source