Results 121 to 130 of about 22,400 (295)
The transcriptional coactivator Querkopf controls adult neurogenesis [PDF]
, 2006 The adult mammalian brain maintains populations of neural stem cells within discrete proliferative zones. Understanding of the molecular mechanisms regulating adult neural stem cell function is limited.
Bartlett, P. F. +6 more
core +2 more sources
The effect of neurosphere culture conditions on the cellular metabolism of glioma cells.
Folia Neuropathologica, 2015 Malignant gliomas, with an average survival time of 16-19 months after initial diagnosis, account for one of the most lethal tumours overall. Current standards in patient care provide only unsatisfying strategies in diagnostic and treatment for high ...
U. Kahlert +9 more
semanticscholar +1 more source
Basic and Clinical Neuroscience, 2021 Introduction: Neurosphere-free transdifferentiation of bone marrow stem cells into Retinal Pigment Epithelium (RPE) and Retinal Cells (RCs) in vitro could offer an exceptional opportunity to study cell replacement in degenerative eye diseases.
Hamid AboutalebKadkhodaeian +2 more
doaj
Small Structures, EarlyView.Herein, the reinforcement of bioactive hydrogels with frog‐derived neuroregenerative peptide (FRNP) is presented to create multifunctional materials with injectability, thermosensitivity, and neurorepair capabilities. The formation of a porous, dual‐network hydrogel structure, combined with the action of FRNP, promotes the proliferation, migration, and
Zhengang Sun +9 more
wiley +1 more source
The development of a ε-polycaprolactone (PCL) scaffold for CNS repair [PDF]
, 2012 Potential treatment strategies for the repair of spinal cord injury (SCI) currently favour a combinatorial approach incorporating several factors, including exogenous cell transplantation and biocompatible scaffolds. The use of scaffolds for bridging the
Gelain F. +9 more
core +1 more source
PLoS ONE, 2014 Recent advances in the in vitro characterization of human adult enteric neural progenitor cells have opened new possibilities for cell-based therapies in gastrointestinal motility disorders. However, whether these cells are able to integrate within an in
S. Hetz +8 more
semanticscholar +1 more source
Conductive Hydrogel‐Based Neural Interfaces: From Fabrication Methods, Properties, to Applications
Small Structures, EarlyView.This review summarizes the fabrication methods, properties, and applications of conductive hydrogels in neural interfaces. Finally, the prevailing challenges and outlines of future directions in the field of conductive hydrogels for neural interfaces are provided, emphasizing the need for interdisciplinary research to address issues such as long‐term ...
Xin‐Yu Xue +10 more
wiley +1 more source
Microglia modulate hippocampal neural precursor activity in response to exercise and aging [PDF]
, 2012 Exercise has been shown to positively augment adult hippocampal neurogenesis; however, the cellular and molecular pathways mediating this effect remain largely unknown. Previous studies have suggested that microglia may have the ability to differentially
Bartlett, Perry F. +4 more
core +2 more sources
Cell Proliferation, EarlyView.A potent combination of small molecules YFSS (Y27632, Forskolin, SB431542, SP600125) that were screened through a neuronal‐specific promoter–reporter system TUBB3::mCherry effectively induces neuronal‐GBM conversion in vitro and in vivo, unveiling molecular mechanisms that offer a theoretical basis and a potential therapeutic strategy for treating GBM.
Ya'nan Hu +12 more
wiley +1 more source
Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. [PDF]
, 2011 Glioblastoma (World Health Organization/WHO grade IV) is the most common and most aggressive adult glial tumor. Patients with glioblastoma, despite being treated with gross total resection and post-operative radiation/chemotherapy, will almost always ...
Choe, Jinny +6 more
core +1 more source