Enteric neurospheres retain the capacity to assemble neural networks with motile and metamorphic gliocytes and ganglia [PDF]
, 2023 Jeng‐Chang Chen +3 more
openalex +1 more source
Neurogastroenterology &Motility, Volume 38, Issue 1, January 2026.The secretory heparan sulphate proteoglycans perlecan, agrin, collagen18A1 are expressed in the periganglionic sheath of enteric ganglia in resectates of Hirschsprung's disease patients and non‐Hirschsprung controls. ABSTRACT Background Secretory heparan sulphate proteoglycans (HSPGs) interact with various morphogens, growth factors, and signaling ...
Nico van den Beld +6 more
wiley +1 more source
Neurospheres: a potential in vitro model for the study of central nervous system disorders
, 2021 Laura da Silva Siqueira +4 more
openalex +2 more sources
Norepinephrine directly activates adult hippocampal precursors via beta(3)-adrenergic receptors [PDF]
, 2010 Adult hippocampal neurogenesis is a critical form of cellular plasticity that is greatly influenced by neural activity. Among the neurotransmitters that are widely implicated in regulating this process are serotonin and norepinephrine, levels of which ...
Bartlett, Perry F. +6 more
core +2 more sources
Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres
Journal of Visualized Experiments, 2018 Epigenetic modifications may be involved in the development and progression of glioma. Changes in methylation and acetylation of promoters and regulatory regions of oncogenes and tumor suppressors can lead to changes in gene expression and play an important role in the pathogenesis of brain tumors.
Flor M, Mendez +4 more
openaire +3 more sources
Exercise Increases Neural Stem Cell Number in a GH-Dependent Manner, Augmenting the Regenerative Response in Aged Mice [PDF]
The exercise-induced enhancement of learning and memory, and its ability to slow age-related cognitive decline in humans led us to investigate whether running stimulates periventricular (PVR) neural stem cells (NSCs) in aging mice, thereby augmenting
Aberg +33 more
core +1 more source
A novel fluorescent reporter CDy1 enriches for neural stem cells derived from the murine brain [PDF]
, 2013 Neurogenesis occurs continuously in two brain regions of adult mammals, underpinned by a pool of resident neural stem cells (NSCs) that can differentiate into all neural cell types.
Bartlett, Perry F. +3 more
core +1 more source
STEM-05. GLIOBLASTOMA NEUROSPHERES DISPLAY STEMNESS CHARACTERISTICS AND UPREGULATION OF THE VEGF-A PATHWAY [PDF]
, 2022 Khashayar Mozaffari +6 more
openalex +1 more source
Porf-2 Inhibits Neural Stem Cell Proliferation Through Wnt/β-Catenin Pathway by Its GAP Domain [PDF]
, 2016 Neural stem cell (NSC) proliferation and differentiation play a pivotal role in the development of brain, the plasticity of the brain network and the repair for brain function in CNS diseases.
Dongfu eFeng +10 more
core +2 more sources
Annali dell'Istituto Superiore di Sanità, 2014 Background. Issues regarding cancer stem cell (CSC) movement are important in neurosphere biology as cell-cell or cell-environment interactions may have significant impacts on CSC differentiation and contribute to the heterogeneity of the neurosphere ...
Giuseppina Bozzuto +6 more
doaj +1 more source