Results 141 to 150 of about 22,415 (298)
An efficient method for the transduction of primary pediatric glioma neurospheres
Pediatric high grade glioma (pHGG) and diffuse intrinsic pontine glioma (DIPG) are rare, but rapidly fatal malignancies of the central nervous system (CNS), and the leading cause of cancer-related death in children. Besides the scarcity of available biological material for research, the study of these diseases has been hampered by methodological ...
Michaël H. Meel+4 more
openaire +4 more sources
Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells [PDF]
The final published version can be found here: http://dx.doi.org/10.1073/pnas ...
Anna Karlsson+18 more
core +1 more source
Sonic hedgehog regulates the proliferation, differentiation, and migration of enteric neural crest cells in gut [PDF]
Enteric neural crest cells (NCCs) migrate and colonize the entire gut and proliferate and differentiate into neurons and glia of the enteric nervous system in vertebrate embryos.
Fu, M+4 more
core +1 more source
Stem cell-based therapy holds great potential especially for neurological disorders. However, clinical applications await further understanding of many aspects of stem cell differentiation and development of technology enabling manipulation of stem cells
Kyuhee Park, Yeonju Nam, Yongmun Choi
semanticscholar +1 more source
Background. Issues regarding cancer stem cell (CSC) movement are important in neurosphere biology as cell-cell or cell-environment interactions may have significant impacts on CSC differentiation and contribute to the heterogeneity of the neurosphere ...
Giuseppina Bozzuto+6 more
doaj +1 more source
Mood stabilising drugs such as lithium (LiCl) and valproic acid (VPA) are the first line agents for treating conditions such as Bipolar disorder and Epilepsy. However, these drugs have potential developmental effects that are not fully understood.
E. Hill+6 more
semanticscholar +1 more source
Injection of Adult Neurospheres Induces Recovery in a Chronic Model of Multiple Sclerosis [PDF]
Guy M. McKhann
openalex +1 more source
MR microscopy of magnetically labeled neurospheres transplanted into the Lewis EAE rat brain [PDF]
Jeff W. M. Bulte+8 more
openalex +1 more source
Isolation and Culture of Adult Zebrafish Brain-derived Neurospheres
The zebrafish is a highly relevant model organism for understanding the cellular and molecular mechanisms involved in neurogenesis and brain regeneration in vertebrates. However, an in-depth analysis of the molecular mechanisms underlying zebrafish adult neurogenesis has been limited due to the lack of a reliable protocol for isolating and culturing ...
Miguel Alejandro Lopez-Ramirez+4 more
openaire +4 more sources
Biomimetic microelectronics for regenerative neuronal cuff implants [PDF]
Smart biomimetics, a unique class of devices combining the mechanical adaptivity of soft actuators with the imperceptibility of microelectronics, is introduced.
Baunack, Stefan+9 more
core +1 more source