Journal of Applied Oral Science, 2021 Objectives Human dental pulp stem cells (DPSCs) have been used to regenerate damaged nervous tissues. However, the methods of committing DPSCs into neural stem/progenitor cells (NSPCs) or neurospheres are highly diverse, resulting in many neuronal ...
Thanasup GONMANEE +4 more
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Characterisation of human gingival neural crest-derived stem cells in monolayer and neurosphere cultures [PDF]
European Cells & Materials, 2016 Neural crest (NC)-derived stem cells (NCSC) have an exceptionally wide differentiation potential, but their use in regenerative therapy has been hampered by their scarcity in adult tissues and complex isolation protocols.
BP Fournier +5 more
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Bio-Protocol, 2016 The hippocampal niche is one of two areas in the brain where stem cells reside. In this neurogenic niche, stem cells can be found in close proximity to astrocytes and in contact with microvessels consisting of pericytes and endothelial cells.
Fanny Ehret +2 more
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Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation
Frontiers in Toxicology, 2022 There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current in vivo guideline studies.
Katharina Koch +10 more
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Effects of FGF-2 and EGF removal on the differentiationof mouse neural precursor cells [PDF]
Anais da Academia Brasileira de Ciências, 2009 Cell therapy for neurological disorders has advanced, and neural precursor cells (NPC) may become the ideal candidates for neural transplantation in a wide range of diseases.
Telma T. Schwindt +7 more
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Developmental neurotoxic effects of Malathion on 3D neurosphere system
Applied & Translational Genomics, 2015 Developmental neurotoxicity (DNT) refers to the toxic effects induced by various chemicals on brain during the early childhood period. As human brains are vulnerable during this period, various chemicals would have significant effects on brains during early childhood.
Mohamed Salama +9 more
semanticscholar +5 more sources
Testosterone-induced adult neurosphere growth is mediated by sexually-dimorphic aromatase expression
Frontiers in Cellular Neuroscience, 2015 We derived adult neural stem/progenitor cells (NSPCs) from the sub-ventricular zone of male and female mice to examine direct responses to principal sex hormones.
Mark Ian Ransome +2 more
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mRNA transfection of mouse and human neural stem cell cultures. [PDF]
PLoS ONE, 2013 The use of synthetic mRNA as an alternative gene delivery vector to traditional DNA-based constructs provides an effective method for inducing transient gene expression in cell cultures without genetic modification.
Samuel McLenachan +4 more
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Neural progenitor cells isolated from the subventricular zone present hemichannel activity and form functional gap junctions with glial cells [PDF]
Frontiers in Cellular Neuroscience, 2015 The postnatal subventricular zone lining the walls of the lateral ventricles contains neural progenitor cells (NPCs) that generate new olfactory bulb interneurons.
Rocío eTalaverón +5 more
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Inhibition of Neurosphere Formation in Neural Stem/Progenitor Cells by Acrylamide
Cell Transplantation, 2015 Previous studies showed that transplantation of cultured neural stem/progenitor cells (NSPCs) could improve functional recovery for various neurological diseases. This study aims to develop a stem cell-based model for predictive toxicology of development
Jong-Hang Chen +4 more
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