Results 11 to 20 of about 22,415 (298)
Journal of Applied Oral Science, 2021 Objectives Human dental pulp stem cells (DPSCs) have been used to regenerate damaged nervous tissues. However, the methods of committing DPSCs into neural stem/progenitor cells (NSPCs) or neurospheres are highly diverse, resulting in many neuronal ...
Thanasup GONMANEE +4 more
doaj +2 more sources
Characterization of neurosphere cell phenotypes by flow cytometry [PDF]
Cytometry, 2000 Neural stem cell research regularly utilizes neurosphere cultures as a continuous source of primitive neural cells. Results from current progenitor cell assays show that these cultures contain a low number of neural progenitors. Our goal is to characterize neurosphere cultures and define subpopulations in order to purify neural progenitor cells.Cells ...
Ruud Hulspas, Peter J. Quesenberry
openalex +4 more sources
537. Further Characterisation of Myo-Neurospheres [PDF]
Molecular Therapy, 2004 Adult stem cells have been isolated from several tissues like bone marrow, brain and skin. We report the isolation and characterisation of neuronal precursor cells, potentially stem cells, from primate and mouse adult muscle and their differentiation in neuronal cells.
Simon Quenneville +4 more
openalex +3 more sources
Characterisation of human gingival neural crest-derived stem cells in monolayer and neurosphere cultures [PDF]
European Cells & Materials, 2016 Neural crest (NC)-derived stem cells (NCSC) have an exceptionally wide differentiation potential, but their use in regenerative therapy has been hampered by their scarcity in adult tissues and complex isolation protocols.
BP Fournier +5 more
doaj +2 more sources
Scientific Validation of Human Neurosphere Assays for Developmental Neurotoxicity Evaluation
Frontiers in Toxicology, 2022 There is a call for a paradigm shift in developmental neurotoxicity (DNT) evaluation, which demands the implementation of faster, more cost-efficient, and human-relevant test systems than current in vivo guideline studies.
Katharina Koch +10 more
doaj +2 more sources
Effects of FGF-2 and EGF removal on the differentiationof mouse neural precursor cells [PDF]
Anais da Academia Brasileira de Ciências, 2009 Cell therapy for neurological disorders has advanced, and neural precursor cells (NPC) may become the ideal candidates for neural transplantation in a wide range of diseases.
Telma T. Schwindt +7 more
doaj +4 more sources
Bio-Protocol, 2016 The hippocampal niche is one of two areas in the brain where stem cells reside. In this neurogenic niche, stem cells can be found in close proximity to astrocytes and in contact with microvessels consisting of pericytes and endothelial cells.
Fanny Ehret +2 more
doaj +3 more sources
Adherent vs. Free-Floating Neural Induction by Dual SMAD Inhibition for Neurosphere Cultures Derived from Human Induced Pluripotent Stem Cells [PDF]
Front. Cell Dev. Biol., 2018 Keeping neural stem cells under proliferation, followed by terminal differentiation, can substantially increase the number of neurons generated. With regard to the usability of proliferating neurospheres (NSPHs) cultures, adherent induction protocols ...
Martje G. Pauly +5 more
semanticscholar +2 more sources
Establishment and phenotyping of neurosphere cultures from primary neuroblastoma samples [PDF]
F1000Research, 2019 Background: Primary cell culture using serum free media supplemented with growth factors has been used in a number of cancers to propagate primary cells with stem like properties, which form as spherical cellular aggregates.
Jack Barton +8 more
semanticscholar +2 more sources
Neurosphere and adherent culture conditions are equivalent for malignant glioma stem cell lines [PDF]
Anatomy & Cell Biology, 2015 Certain limitations of the neurosphere assay (NSA) have resulted in a search for alternative culture techniques for brain tumor-initiating cells (TICs). Recently, reports have described growing glioblastoma (GBM) TICs as a monolayer using laminin.
Maryam Rahman +11 more
semanticscholar +2 more sources