Results 241 to 250 of about 17,973 (254)

Magnetic manipulation of bacterial magnetic nanoparticle-loaded neurospheres

Integrative Biology, 2014
Specific targeting of cells to sites of tissue damage and delivery of high numbers of transplanted cells to lesion tissue in vivo are critical parameters for the success of cell-based therapies. Here, we report a promising in vitro model system for studying the homing of transplanted cells, which may eventually be applicable for targeted regeneration ...
Jaeha, Shin, Kyung-Mee, Lee, Jae Hyup, Lee, Junghoon, Lee, Misun, Cha   +4 more
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Strengths and Limitations of the Neurosphere Culture System

Molecular Neurobiology, 2006
After the initial reports of free-floating cultures of neural stem cells termed neurospheres (1,2), a wide array of studies using this promising culture system emerged. In theory, this was a near-perfect system for large-scale production of neural cells for use in cell replacement therapies and to assay for and characterize neural stem cells. More than
Josephine B, Jensen, Malin, Parmar
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Isolation and culture of adult neurons and neurospheres

Nature Protocols, 2007
Here we present a protocol for extraction and culture of neurons from adult rat or mouse CNS. The method proscribes an optimized protease digestion of slices, control of osmolarity and pH outside the incubator with Hibernate and density gradient separation of neurons from debris.
Gregory J, Brewer, John R, Torricelli
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Neurospheres as a Model for Developmental Neurotoxicity Testing

2011
Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. So far, DNT testing is performed in animals. Such in vivo testing is time-consuming, expensive, and uses large numbers of animals. Moreover, species differences (rat-human) bear the problem of extrapolation.
Ellen, Fritsche, Kathrin, Gassmann, Timm, Schreiber   +2 more
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The mechanical effects of chemical stimuli on neurospheres

Biomechanics and Modeling in Mechanobiology
The formulation of more accurate models to describe tissue mechanics necessitates the availability of tools and instruments that can precisely measure the mechanical response of tissues to physical loads and other stimuli. In this regard, neuroscience has trailed other life sciences owing to the unavailability of representative live tissue models and ...
Yun-Han, Huang, Roza, Vaez Ghaemi, James, Cheon, Vikramaditya G, Yadav, John M, Frostad   +4 more
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Neurosphere culture derived from aged hippocampal dentate gyrus

AbstractThe neurosphere assay is the gold standard for determining proliferative and differentiation potential of neural progenitor cells (NPCs) in neurogenesis studies1–3. While severalin vitroassays have been developed to model the process of neurogenesis, they have predominantly used embryonic and early postnatal NPCs derived from the dentate gyrus (
Olga Vafaeva, Poommaree Namchaiw, Karl Murray, Elva Diaz, Hwai-Jong Cheng   +4 more
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The effect of trichloroethylene on neurosphere

Toxicology Letters, 2015
S. Ismail, M. Salama, A. Lotfy, M. Elgamal, H. Sheashaa, M. Sobh, N. Mohy, E. Abu El-yazid   +7 more
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Enzyme solution for neurosphere assay

Cold Spring Harbor Protocols, 2008
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Neurosphere Culture

2009
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179. Effect of papaverine on neurospheres

Toxicon, 2015
Noura Shehab-Eldeen, Mohamed Salama, Ahmed Lotfy, Mohamed Elgamal, Hussein Sheashaa, Mohamed Sobh, Mohamed Elsherbeeny, Hossam Elmetwally   +7 more
openaire   +1 more source