Results 21 to 30 of about 22,400 (295)

Characterization of neurosphere cell phenotypes by flow cytometry [PDF]

open access: bronzeCytometry, 2000
Neural stem cell research regularly utilizes neurosphere cultures as a continuous source of primitive neural cells. Results from current progenitor cell assays show that these cultures contain a low number of neural progenitors. Our goal is to characterize neurosphere cultures and define subpopulations in order to purify neural progenitor cells.Cells ...
Ruud Hulspas, Peter J. Quesenberry
openalex   +4 more sources

537. Further Characterisation of Myo-Neurospheres [PDF]

open access: hybridMolecular Therapy, 2004
Adult stem cells have been isolated from several tissues like bone marrow, brain and skin. We report the isolation and characterisation of neuronal precursor cells, potentially stem cells, from primate and mouse adult muscle and their differentiation in neuronal cells.
Simon Quenneville   +4 more
openalex   +3 more sources

Enteric Neurospheres Are Not Specific to Neural Crest Cultures: Implications for Neural Stem Cell Therapies [PDF]

open access: yes, 2015
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
A Barlow   +61 more
core   +26 more sources

Adherent vs. Free-Floating Neural Induction by Dual SMAD Inhibition for Neurosphere Cultures Derived from Human Induced Pluripotent Stem Cells [PDF]

open access: goldFront. Cell Dev. Biol., 2018
Keeping neural stem cells under proliferation, followed by terminal differentiation, can substantially increase the number of neurons generated. With regard to the usability of proliferating neurospheres (NSPHs) cultures, adherent induction protocols ...
Martje G. Pauly   +5 more
openalex   +2 more sources

Neurosphere and adherent culture conditions are equivalent for malignant glioma stem cell lines [PDF]

open access: greenAnatomy & Cell Biology, 2015
Certain limitations of the neurosphere assay (NSA) have resulted in a search for alternative culture techniques for brain tumor-initiating cells (TICs). Recently, reports have described growing glioblastoma (GBM) TICs as a monolayer using laminin.
Maryam Rahman   +11 more
openalex   +2 more sources

Establishment and phenotyping of neurosphere cultures from primary neuroblastoma samples [PDF]

open access: goldF1000Research, 2019
Background: Primary cell culture using serum free media supplemented with growth factors has been used in a number of cancers to propagate primary cells with stem like properties, which form as spherical cellular aggregates.
Jack Barton   +8 more
openalex   +2 more sources

Accelerating the in vitro emulation of Alzheimer’s disease-associated phenotypes using a novel 3D blood-brain barrier neurosphere co-culture model

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
High failure rates in clinical trials for neurodegenerative disorders such as Alzheimer’s disease have been linked to an insufficient predictive validity of current animal-based disease models. This has created an increasing demand for alternative, human-
Eunkyung Clare Ko   +12 more
semanticscholar   +1 more source

Valproic acid enhances neurosphere formation in cultured rat embryonic cortical cells through TGFβ1 signaling

open access: yesJournal of Biomedical Research, 2022
This study aimed to investigate the effect and mechanism of valproic acid (VPA) on the neurosphere formation in rat embryonic cortical cells. We used free-floating neurosphere formation as a model system to evaluate the VPA on the proliferation of neural
C. Qi   +5 more
semanticscholar   +1 more source

A tenascin-C mimetic peptide amphiphile nanofiber gel promotes neurite outgrowth and cell migration of neurosphere-derived cells

open access: bronzeActa Biomaterialia, 2016
Eric J. Berns   +6 more
openalex   +3 more sources

Prion infection of mouse neurospheres [PDF]

open access: yesProceedings of the National Academy of Sciences, 2006
Only a few cell lines have been infected with prions, offering limited genetic diversity and sensitivity to several strains. Here we report that cultured neurospheres expressing cellular prion protein (PrP C ) can be infected with prions. Neurosphere lines isolated from the brains of mice at embryonic day 13–15 grow
George A. Carlson   +5 more
openaire   +3 more sources

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