Results 21 to 30 of about 22,400 (295)
Characterization of neurosphere cell phenotypes by flow cytometry [PDF]
Neural stem cell research regularly utilizes neurosphere cultures as a continuous source of primitive neural cells. Results from current progenitor cell assays show that these cultures contain a low number of neural progenitors. Our goal is to characterize neurosphere cultures and define subpopulations in order to purify neural progenitor cells.Cells ...
Ruud Hulspas, Peter J. Quesenberry
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537. Further Characterisation of Myo-Neurospheres [PDF]
Adult stem cells have been isolated from several tissues like bone marrow, brain and skin. We report the isolation and characterisation of neuronal precursor cells, potentially stem cells, from primate and mouse adult muscle and their differentiation in neuronal cells.
Simon Quenneville+4 more
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Enteric Neurospheres Are Not Specific to Neural Crest Cultures: Implications for Neural Stem Cell Therapies [PDF]
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work ...
A Barlow+61 more
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Adherent vs. Free-Floating Neural Induction by Dual SMAD Inhibition for Neurosphere Cultures Derived from Human Induced Pluripotent Stem Cells [PDF]
Keeping neural stem cells under proliferation, followed by terminal differentiation, can substantially increase the number of neurons generated. With regard to the usability of proliferating neurospheres (NSPHs) cultures, adherent induction protocols ...
Martje G. Pauly+5 more
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Neurosphere and adherent culture conditions are equivalent for malignant glioma stem cell lines [PDF]
Certain limitations of the neurosphere assay (NSA) have resulted in a search for alternative culture techniques for brain tumor-initiating cells (TICs). Recently, reports have described growing glioblastoma (GBM) TICs as a monolayer using laminin.
Maryam Rahman+11 more
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Establishment and phenotyping of neurosphere cultures from primary neuroblastoma samples [PDF]
Background: Primary cell culture using serum free media supplemented with growth factors has been used in a number of cancers to propagate primary cells with stem like properties, which form as spherical cellular aggregates.
Jack Barton+8 more
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High failure rates in clinical trials for neurodegenerative disorders such as Alzheimer’s disease have been linked to an insufficient predictive validity of current animal-based disease models. This has created an increasing demand for alternative, human-
Eunkyung Clare Ko+12 more
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This study aimed to investigate the effect and mechanism of valproic acid (VPA) on the neurosphere formation in rat embryonic cortical cells. We used free-floating neurosphere formation as a model system to evaluate the VPA on the proliferation of neural
C. Qi+5 more
semanticscholar +1 more source
Prion infection of mouse neurospheres [PDF]
Only a few cell lines have been infected with prions, offering limited genetic diversity and sensitivity to several strains. Here we report that cultured neurospheres expressing cellular prion protein (PrP C ) can be infected with prions. Neurosphere lines isolated from the brains of mice at embryonic day 13–15 grow
George A. Carlson+5 more
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