Results 51 to 60 of about 22,400 (295)

Isolation and Culture of Neurospheres for the Study of Pathogenesis of Prion Disease

open access: yesBio-Protocol, 2014
Neurosphere contains neural stem cells that are capable of self-renewal and multilineage differentiation including neurons, astrocytes, and oligodendrocytes (Gage, 2000).
Yoshi Iwamaru   +2 more
doaj   +1 more source

Prokineticin 2 Is a Target Gene of Proneural Basic Helix-Loop-Helix Factors for Olfactory Bulb Neurogenesis [PDF]

open access: yes, 2007
Prokineticin 2, a cysteine-rich secreted protein, regulates diverse biological functions including the neurogenesis of olfactory bulb. Here we show that the PK2 gene is a functional target gene of proneural basic helix-loop-helix (bHLH) factors ...
Anderson, David J.   +6 more
core   +1 more source

Astroglial-axonal interactions during early stages of myelination in mixed cultures using in vitro and ex vivo imaging techniques [PDF]

open access: yes, 2014
<b>Background</b><p></p> Myelination is a very complex process that requires the cross talk between various neural cell types.
Anderson, Kurt I   +4 more
core   +2 more sources

Production of Neurospheres from CNS Tissue [PDF]

open access: yes, 2008
The relatively recent discovery of persistent adult neurogenesis has led to the experimental isolation and characterization of central nervous system neural stem cell populations. Protocols for in vitro analysis and expansion of neural stem cells are crucial for understanding their properties and defining characteristics.
Dennis A. Steindler   +5 more
openaire   +3 more sources

Transplantation of Embryonic Neural Stem Cells and Differentiated Cells in a Controlled Cortical Impact (CCI) Model of Adult Mouse Somatosensory Cortex

open access: yesFrontiers in Neurology, 2018
Traumatic brain injury (TBI) is a major cause of death worldwide. Depending on the severity of the injury, TBI can reflect a broad range of consequences such as speech impairment, memory disturbances, and premature death.
Mohammad Nasser   +11 more
doaj   +1 more source

Effect of Epoxomicin on 3D Neurosphere [PDF]

open access: yes, 2014
Developmental neurotoxicity (DNT) entails the toxic effects imparted by many chemicals on brain during early childhood. Various chemicals would have their maximum effects on brains during early childhood. Some toxicants have confirmed to induce developmental toxic effects on CNS.
Khaled Youssef   +7 more
openaire   +2 more sources

Direct generation of neurosphere-like cells from human dermal fibroblasts. [PDF]

open access: yesPLoS ONE, 2011
Neural stem cell (NSC) transplantation replaces damaged brain cells and provides disease-modifying effects in many neurological disorders. However, there has been no efficient way to obtain autologous NSCs in patients.
Soon-Tae Lee   +8 more
doaj   +1 more source

Docosahexaenoic Acid and Melatonin Prevent Impaired Oligodendrogenesis Induced by Intrauterine Growth Restriction (IUGR)

open access: yesBiomedicines, 2022
In this study, our aims were to characterize oligodendrogenesis alterations in fetuses with intrauterine growth restriction (IUGR) and to find therapeutic strategies to prevent/treat them using a novel rabbit in vitro neurosphere culture.
Britta Anna Kühne   +8 more
doaj   +1 more source

Disease-specific, neurosphere-derived cells as models for brain disorders [PDF]

open access: yes, 2010
There is a pressing need for patient-derived cell models of brain diseases that are relevant and robust enough to produce the large quantities of cells required for molecular and functional analyses.
Abrahamsen, G.   +29 more
core   +1 more source

Elimination of the geomagnetic field stimulates the proliferation of mouse neural progenitor and stem cells

open access: yesProtein & Cell, 2016
Living organisms are exposed to the geomagnetic field (GMF) throughout their lifespan. Elimination of the GMF, resulting in a hypogeomagnetic field (HMF), leads to central nervous system dysfunction and abnormal development in animals.
Jing-Peng Fu   +4 more
doaj   +1 more source

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