Results 71 to 80 of about 22,400 (295)
Advanced Functional Materials, EarlyView.Spinal cord injury (SCI) poses significant challenges for regeneration due to a series of secondary injury mechanisms. How to use biomaterial approach to target the failed regeneration after SCI remains a critical challenge. This review systematically evaluates current strategies to optimize biomaterial topographies for neurite outgrowth, axonal ...
Wei Xu +7 more
wiley +1 more source
Requirement of Pax6 for the integration of guidance cues in cell migration [PDF]
, 2017 Data accessibility. Cell trajectories data and a summary of directedness and angle values are deposited at Dryad: http://dx.doi.org/10.5061/dryad.53512.
Arocena, Miguel +2 more
core +1 more source
Toxicological Sciences, 2016 The practical application of engineered nanomaterials or nanoparticles like polyamidoamine (PAMAM) dendrimers has been promoted in medical devices or industrial uses.
Yang Zeng +6 more
semanticscholar +1 more source
Cryopreservation of Neurospheres Derived from Human Glioblastoma Multiforme [PDF]
Stem Cells, 2009 Abstract Cancer stem cells have been shown to initiate and sustain tumor growth. In many instances, clinical material is limited, compounded by a lack of methods to preserve such cells at convenient time points. Although brain tumor-initiating cells grown in a spheroid manner have been shown to maintain their integrity through serial ...
Yuk-Kien Chong +16 more
openaire +3 more sources
Frontiers in Aging Neuroscience, 2017 Impairment of hippocampal adult neurogenesis in aging or degenerating brain is a well-known phenomenon caused by the shortage of brain stem cell pool, alterations in the local microenvironment within the neurogenic niches, or deregulation of stem cell ...
Vladimir V. Salmin +15 more
doaj +1 more source
Determination of somatic and cancer stem cell self-renewing symmetric division rate using sphere assays. [PDF]
PLoS ONE, 2011 Representing a renewable source for cell replacement, neural stem cells have received substantial attention in recent years. The neurosphere assay represents a method to detect the presence of neural stem cells, however owing to a deficiency of specific ...
Loic P Deleyrolle +8 more
doaj +1 more source
Smart Polymeric 3D Microscaffolds Hosting Spheroids for Neuronal Research via Quantum Metrology
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.Development of a platform consisting of 3D microscaffolds supporting 3D embryoid bodies for neuronal research. The polymeric scaffolds enable directed growth of neurites. This study shows nanodiamond‐based quantum sensors graft onto the polymer material, enabling quantum metrology experiments within the 3D neuronal model and thereby providing a ...
Beatriz N. L. Costa +5 more
wiley +1 more source
Differential sensitivity of Glioma stem cells to Aurora kinase A inhibitors: implications for stem cell mitosis and centrosome dynamics [PDF]
, 2014 Glioma stem-cell-like cells are considered to be responsible for treatment resistance and tumour recurrence following chemo-radiation in glioblastoma patients, but specific targets by which to kill the cancer stem cell population remain elusive.
Chalmers, Anthony J. +3 more
core +3 more sources
Stem Cells and Development, 2015 Cell-based therapies are emerging as an alternative treatment option to promote functional recovery in patients suffering from neurological disorders, which are the major cause of death and permanent disability.
P. Gervois +8 more
semanticscholar +1 more source
Zika virus disrupts molecular fingerprinting of human neurospheres [PDF]
Scientific Reports, 2017 AbstractZika virus (ZIKV) has been associated with microcephaly and other brain abnormalities; however, the molecular consequences of ZIKV to human brain development are still not fully understood. Here we describe alterations in human neurospheres derived from induced pluripotent stem (iPS) cells infected with the strain of Zika virus that is ...
Luiza M. Higa +18 more
openaire +2 more sources