Results 81 to 90 of about 17,973 (254)

Spinal Progenitor-Laden Bridges Support Earlier Axon Regeneration Following Spinal Cord Injury. [PDF]

open access: yes, 2018
Impact statementSpinal cord injury (SCI) results in loss of tissue innervation below the injury. Spinal progenitors have a greater ability to repair the damage and can be injected into the injury, but their regenerative potential is hampered by their ...
Anderson, Aileen J   +5 more
core   +1 more source

Selective Promotion of Retinal Organoid Attachment and Differentiation by Amine‐ and Hydroxyl‐Modified Surfaces

open access: yesAdvanced NanoBiomed Research, EarlyView.
Engineered biomaterial interfaces critically control retinal organoid development. This study examines how surface modifications (amine, hydroxyl, phenyl, and methyl groups) dictate organoid response. Hydrophilic surfaces markedly increase migration and foster retinal ganglion cell differentiation.
Luis Marcos   +4 more
wiley   +1 more source

Testosterone-induced adult neurosphere growth is mediated by sexually-dimorphic aromatase expression

open access: yesFrontiers in Cellular Neuroscience, 2015
We derived adult neural stem/progenitor cells (NSPCs) from the sub-ventricular zone of male and female mice to examine direct responses to principal sex hormones.
Mark Ian Ransome   +2 more
doaj   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Enhancing Neural Stem Cell Proliferation Using Polyurethane/CNT Scaffolds Functionalized With Liposomal Hesperidin for Neural Tissue Engineering

open access: yesNano Select, EarlyView.
A multifunctional electrospun scaffold combining polyurethane, carbon nanotubes, and liposomal hesperidin supports neural stem cell survival, adhesion, and expansion. This platform enhances conductivity, mechanical strength, and hydrophilicity while mimicking the native neural environment.
Arman Abroumand Gholami   +8 more
wiley   +1 more source

LPC18:0 Secreted by Exogenous Neural Stem Cells Potentiates Neurogenesis and Functional Recovery via GPR55‐Mediated Signalling in Spinal Cord Injury

open access: yesCell Proliferation, EarlyView.
LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen   +11 more
wiley   +1 more source

Characterization of neurosphere cell phenotypes by flow cytometry [PDF]

open access: yesCytometry, 2000
Neural stem cell research regularly utilizes neurosphere cultures as a continuous source of primitive neural cells. Results from current progenitor cell assays show that these cultures contain a low number of neural progenitors. Our goal is to characterize neurosphere cultures and define subpopulations in order to purify neural progenitor cells.Cells ...
R, Hulspas, P J, Quesenberry
openaire   +2 more sources

The transcriptional coactivator Querkopf controls adult neurogenesis [PDF]

open access: yes, 2006
The adult mammalian brain maintains populations of neural stem cells within discrete proliferative zones. Understanding of the molecular mechanisms regulating adult neural stem cell function is limited.
Bartlett, P. F.   +6 more
core   +2 more sources

Ethanol induces cell-cycle activity and reduces stem cell diversity to alter both regenerative capacity and differentiation potential of cerebral cortical neuroepithelial precursors

open access: yesBMC Neuroscience, 2005
Background The fetal cortical neuroepithelium is a mosaic of distinct progenitor populations that elaborate diverse cellular fates. Ethanol induces apoptosis and interferes with the survival of differentiating neurons.
Tingling Joseph D   +5 more
doaj   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

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