Results 81 to 90 of about 22,415 (298)
Journal of Pain Research, 2021 Timothy R Deer,1 Michael F Esposito,2 Eric G Cornidez,3 Udoka Okaro,4 Marie E Fahey,4 Kenneth B Chapman5 1Spine and Nerve Center of the Virginias, Charleston, WV, USA; 2Florida Pain Institute, Melbourne, FL, USA; 3Pain Institute of Southern Arizona ...
Deer TR +5 more
doaj
Determination of somatic and cancer stem cell self-renewing symmetric division rate using sphere assays. [PDF]
PLoS ONE, 2011 Representing a renewable source for cell replacement, neural stem cells have received substantial attention in recent years. The neurosphere assay represents a method to detect the presence of neural stem cells, however owing to a deficiency of specific ...
Loic P Deleyrolle +8 more
doaj +1 more source
Advanced Science, EarlyView.This study investigates the role of group 2 innate lymphoid cells (ILC2) in the choroid plexus (ChP) following traumatic brain injury (TBI). ILC2 accumulation alleviates immune infiltration, preserves hippocampal integrity, and improves sensory‐motor and memory functions.
Shiqi Gao +10 more
wiley +1 more source
OncoTarget, 2017 Nitric oxide has been implicated in biology and progression of glioblastoma (GBM) being able to influence the cellular signal depending on the concentration and duration of cell exposure.
P. Palumbo +9 more
semanticscholar +1 more source
Cryopreservation of Neurospheres Derived from Human Glioblastoma Multiforme [PDF]
Stem Cells, 2009 Abstract Cancer stem cells have been shown to initiate and sustain tumor growth. In many instances, clinical material is limited, compounded by a lack of methods to preserve such cells at convenient time points. Although brain tumor-initiating cells grown in a spheroid manner have been shown to maintain their integrity through serial ...
Yuk-Kien Chong +16 more
openaire +3 more sources
FKBP38 Regulates Self-Renewal and Survival of GBM Neurospheres
Cells, 2023 Glioblastoma is the most common malignant primary brain tumor. The outcome is dismal, despite the multimodal therapeutic approach that includes surgical resection, followed by radiation and chemotherapy. The quest for novel therapeutic targets to treat glioblastoma is underway.
Aimee L. Dowling +11 more
openaire +3 more sources
Comparative Analysis of the Frequency and Distribution of Stem and Progenitor Cells in the Adult Mouse Brain [PDF]
cells (NSCs) and progenitor cells, but it cannot discriminate between these two populations. Given two assays have purported to overcome this shortfall, we performed a comparative analysis of the distribution and frequency of NSCs and progenitor ...
Aguirre +64 more
core +1 more source
Stem and progenitor cells: Origins, phenotypes, lineage commitments, and transdifferentiations [PDF]
, 2001 Multipotent stem cells are clonal cells that self-renew as well as differentiate to regenerate adult tissues. Whereas stem cells and their fates are known by unique genetic marker studies, the fate and function of these cells are best studied by their ...
Anderson, David J. +2 more
core +1 more source
Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis
Advanced Science, EarlyView.Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu +17 more
wiley +1 more source
Zika virus disrupts molecular fingerprinting of human neurospheres [PDF]
Scientific Reports, 2017 AbstractZika virus (ZIKV) has been associated with microcephaly and other brain abnormalities; however, the molecular consequences of ZIKV to human brain development are still not fully understood. Here we describe alterations in human neurospheres derived from induced pluripotent stem (iPS) cells infected with the strain of Zika virus that is ...
Luiza M. Higa +18 more
openaire +2 more sources