Establishment of Neurospora crassa as a model organism for fungal virology
Nature Communications, 2020 The fungus Neurospora crassa is a model organism for the study of various biological processes, but it is not known to be infected by any viruses. Here, Honda et al. identify RNA viruses that infect N.
Shinji Honda +7 more
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Identification of a common secondary mutation in the Neurospora crassa knockout collection conferring a cell fusion-defective phenotype [PDF]
Microbiology Spectrum, 2023 Gene-deletion mutants represent a powerful tool to study gene function. The filamentous fungus Neurospora crassa is a well-established model organism, and features a comprehensive gene knockout strain collection. While these mutant strains have been used
Alejandro Montenegro-Montero +3 more
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Gene expression differences among three Neurospora species reveal genes required for sexual reproduction in Neurospora crassa. [PDF]
PLoS ONE, 2014 Many fungi form complex three-dimensional fruiting bodies, within which the meiotic machinery for sexual spore production has been considered to be largely conserved over evolutionary time.
Nina A Lehr +6 more
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Secret lifestyles of Neurospora crassa [PDF]
Scientific Reports, 2014 AbstractNeurospora crassa has a long history as an excellent model for genetic, cellular and biochemical research. Although this fungus is known as a saprotroph, it normally appears on burned vegetations or trees after forest fires. However, due to a lack of experimental evidence, the nature of its association with living plants remains enigmatic. Here
Kuo, Hsiao-Che +5 more
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The bZIP Transcription Factor HAC-1 Is Involved in the Unfolded Protein Response and Is Necessary for Growth on Cellulose in Neurospora crassa. [PDF]
PLoS ONE, 2015 High protein secretion capacity in filamentous fungi requires an extremely efficient system for protein synthesis, folding and transport. When the folding capacity of the endoplasmic reticulum (ER) is exceeded, a pathway known as the unfolded protein ...
Alejandro Montenegro-Montero +2 more
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Human-like eukaryotic translation initiation factor 3 from Neurospora crassa. [PDF]
PLoS ONE, 2013 Eukaryotic translation initiation factor 3 (eIF3) is a key regulator of translation initiation, but its in vivo assembly and molecular functions remain unclear.
M Duane Smith +5 more
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Developing a Temperature-Inducible Transcriptional Rheostat in Neurospora crassa [PDF]
mBio, 2023 Heat shock protein (HSP)-encoding genes (hsp), part of the highly conserved heat shock response (HSR), are known to be induced by thermal stress in several organisms. In Neurospora crassa, three hsp genes, hsp30, hsp70, and hsp80, have been characterized;
Cyndi Tabilo-Agurto +5 more
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mBio, 2016 Rapid responses to changes in incident light are critical to the guidance of behavior and development in most species. Phytochrome light receptors in particular play key roles in bacterial physiology and plant development, but their functions and ...
Zheng Wang +5 more
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HDA-2-Containing Complex Is Required for Activation of Catalase-3 Expression in Neurospora crassa [PDF]
mBio, 2022 It is essential for aerobic organisms to maintain the homeostasis of intracellular reactive oxygen species (ROS) for survival and adaptation to the environment.
Lingaonan He +6 more
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A user-friendly CRISPR/Cas9 system for mutagenesis of Neurospora crassa [PDF]
Scientific ReportsAs a widely used eukaryotic model organism, Neurospora crassa offers advantages in genetic studies due to its diverse biology and rapid growth. Traditional genetic manipulation methods, such as homologous recombination, require a considerable amount of ...
Stefanie Grüttner, Frank Kempken
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