Establishment of Neurospora crassa as a model organism for fungal virology
The fungus Neurospora crassa is a model organism for the study of various biological processes, but it is not known to be infected by any viruses. Here, Honda et al. identify RNA viruses that infect N.
Shinji Honda+7 more
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Metabolic Impacts of Using Nitrogen and Copper-Regulated Promoters to Regulate Gene Expression in Neurospora crassa. [PDF]
The filamentous fungus Neurospora crassa is a long-studied eukaryotic microbial system amenable to heterologous expression of native and foreign proteins. However, relatively few highly tunable promoters have been developed for this species.
Beecher, Consuelo N+4 more
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Background Regulation of chromatin accessibility and transcription are tightly coordinated processes. Studies in yeast and higher eukaryotes have described accessible chromatin regions, but little work has been done in filamentous fungi.
Aileen R. Ferraro+5 more
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Conidiation in Neurospora crassa: vegetative reproduction by a model fungus [PDF]
Asexual development, conidiation, in the filamentous fungus Neurospora crassa is a simple developmental process that starts with the growth of aerial hyphae.
Corrochano Peláez, Luis María+1 more
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Structural analyses of the translating mitoribosome from Neurospora crassa reveal insights into the interactions with mRNA and tRNA, assembly of the large subunit, and evolution of the tunnel for nascent polypeptide.
Yuzuru Itoh+4 more
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Relationship between phylogenetic distribution and genomic features in Neurospora crassa. [PDF]
In the post-genome era, insufficient functional annotation of predicted genes greatly restricts the potential of mining genome data. We demonstrate that an evolutionary approach, which is independent of functional annotation, has great potential as a ...
Takao Kasuga+2 more
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Functional Profiling of Transcription Factor Genes in Neurospora crassa. [PDF]
Regulation of gene expression by DNA-binding transcription factors is essential for proper control of growth and development in all organisms. In this study, we annotate and characterize growth and developmental phenotypes for transcription factor genes ...
Bekman, Thomas+17 more
core +1 more source
Optimization of glycerol-based medium composition for antifungal metabolites production by Bacillus subtilis [PDF]
Bacillus species are promising producers of various compounds that have pronounced antimicrobial, antiviral and antitumor activities. Due to its GRAS status, Bacillus subtilis represents an excellent candidate for the usage in plant pathogens biocontrol.
Zorana Rončević+6 more
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Analysis of a conserved cellulase transcriptional regulator reveals inducer-independent production of cellulolytic enzymes in Neurospora crassa. [PDF]
Cellulose is recalcitrant to deconstruction to glucose for use in fermentation strategies for biofuels and chemicals derived from lignocellulose. In Neurospora crassa, the transcriptional regulator, CLR-2, is required for cellulolytic gene expression and
Coradetti, Samuel+2 more
core +2 more sources
Suppressors of Meiotic Silencing by Unpaired DNA
Meiotic silencing by unpaired DNA (MSUD) is a gene silencing process that occurs within meiotic cells of Neurospora crassa and other fungi. We have previously developed a high-throughput screen to identify suppressors of this silencing pathway.
Hua Xiao+2 more
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