Results 51 to 60 of about 35,266 (337)

Sildenafil Citrate-Restored eNOS and PDE5 Regulation in Sickle Cell Mouse Penis Prevents Priapism Via Control of Oxidative/Nitrosative Stress [PDF]

, 2013
Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical phosphodiesterase type 5 inhibitor indicated for the treatment of male erectile dysfunction.
Berkowitz, DE, Bivalacqua, TJ, Burnett, AL, Champion, HC, Hsu, LL, Musicki, B   +5 more
core   +7 more sources

Neurostimulation as a Method of Treatment and a Preventive Measure in Canine Drug-Resistant Epilepsy: Current State and Future Prospects

Frontiers in Veterinary Science, 2022
Modulation of neuronal activity for seizure control using various methods of neurostimulation is a rapidly developing field in epileptology, especially in treatment of refractory epilepsy.
Marta Nowakowska, Muammer Üçal, Marios Charalambous, Sofie F. M. Bhatti, Timothy Denison, Sebastian Meller, Gregory A. Worrell, Heidrun Potschka, Holger A. Volk   +8 more
doaj   +1 more source

Making Waves in the Brain: What Are Oscillations, and Why Modulating Them Makes Sense for Brain Injury. [PDF]

, 2016
Traumatic brain injury (TBI) can result in persistent cognitive, behavioral and emotional deficits. However, the vast majority of patients are not chronically hospitalized; rather they have to manage their disabilities once they are discharged to home ...
Gurkoff, Gene G, Izadi, Ali, Lee, Darrin J, Pevzner, Aleksandr, Shahlaie, Kiarash   +4 more
core   +1 more source

Responsive neurostimulation with low‐frequency stimulation

Epilepsia, 2022
Deep brain stimulation and responsive neurostimulation (RNS) use high‐frequency stimulation (HFS) per the pivotal trials and manufacturer‐recommended therapy protocols. However, not all patients respond to HFS.
J. Alcala-Zermeno, K. Starnes, N. Gregg, G. Worrell, B. Lundstrom   +4 more
semanticscholar   +1 more source

Impairment of Procedural Learning and Motor Intracortical Inhibition in Neurofibromatosis Type 1 Patients

EBioMedicine, 2015
Background: Cognitive difficulties are the most common neurological complications in neurofibromatosis type 1 (NF1) patients. Recent animal models proposed increased GABA-mediated inhibition as one underlying mechanism directly affecting the induction of
Máximo Zimerman, Maximilian J. Wessel, Jan E. Timmermann, Sofia Granström, Christian Gerloff, Victor F. Mautner, Friedhelm C. Hummel   +6 more
doaj   +1 more source

Intracranial electroencephalographic biomarker predicts effective responsive neurostimulation for epilepsy prior to treatment

Epilepsia, 2022
Despite the overall success of responsive neurostimulation (RNS) therapy for drug‐resistant focal epilepsy, clinical outcomes in individuals vary significantly and are hard to predict.
B. Scheid, J. Bernabei, A. Khambhati, Sofia Mouchtaris, Jay Jeschke, D. Bassett, D. Becker, K. Davis, T. Lucas, W. Doyle, E. Chang, D. Friedman, V. Rao, B. Litt   +13 more
semanticscholar   +1 more source

Noninvasive brain stimulation and auditory verbal hallucinations: new techniques and future directions

Frontiers in Neuroscience, 2016
Auditory verbal hallucinations (AVHs) are the experience of hearing a voice in the absence of any speaker. Results from recent attempts to treat AVHs with neurostimulation (rTMS or tDCS) to the left temporoparietal junction have not been conclusive, but ...
Peter eMoseley, Ben eAlderson-Day, Amanda eEllison, Renaud eJardri, Charles eFernyhough   +4 more
doaj   +1 more source

A computational roadmap to electronic drugs

Frontiers in Neurorobotics, 2022
A growing number of complex neurostimulation strategies promise symptom relief and functional recovery for several neurological, psychiatric, and even multi-organ disorders.
Andreas Rowald, Oliver Amft, Oliver Amft, Oliver Amft   +3 more
doaj   +1 more source

Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]

, 2012
Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape, B. Zwissler, Barton RG, Cain SM, Eisenberg E, Fontana JL, H. Kertscho, Habler OP, Haller M, Herweling A, Holt JP, Ickx BE, Kampe S, Kemming GI, Kim J, Koskolou MD, Levy PS, M. Lossen, Madjdpour C, Marik PE, McCall M, Meier J, Meier JM, Meier JM, Meier JM, Meisner FG, Messmer KF, Muldoon SM, Naguib M, O. Habler, O. Horn, P. Stein, Pape A, Pape A, Pape A, Perez V, Pittman RN, Richardson RS, Russell WC, S. Kutschker, Schumacker PT, van der Linden P, van der Linden P, van Woerkens EC, Vernon DD, Werlhof V, Zollinger A   +46 more
core   +1 more source

Responsive Neurostimulation of the Thalamus for the Treatment of Refractory Epilepsy

Frontiers in Human Neuroscience, 2022
Introduction One-third of patients with epilepsy continue to have seizures despite antiepileptic medications. Some of these refractory patients may not be candidates for surgical resection primarily because the seizure onset zones (SOZs) involve both ...
Jorge A. Roa, M. Abramova, M. Fields, Maite La Vega-Talbott, Jiyeoun Yoo, L. Marcuse, S. Wolf, P. McGoldrick, S. Ghatan, Fedor Panov   +9 more
semanticscholar   +1 more source