Results 101 to 110 of about 479,147 (344)

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

Advanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee, Rut Tejero, Nathaniel Silvia, Anirudh Sattiraju, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Roland H. Friedel, Hongyan Zou, Guohao Dai   +10 more
wiley   +1 more source

Operative Neurosurgery: With Emphasis on Procedures in Trauma [PDF]

, 1953
E. S. Gurdjian, J. E. Webster
openalex   +1 more source

Type I Interferon Signaling Augments Autoimmunity in Neuromyelitis Optica Spectrum Disorder

Advanced Science, EarlyView.
The cGAS‐STING innate immune pathway is excessively activated both in peripheral monocytes and CNS microglia in patients with NMOSD, leading to an overproduction of IFN‐I. IFN‐I subsequently acts on AQP4‐specific autoreactive T cells. Blocking this pathway may offer novel therapeutic options for individuals with NMOSD.
Tian‐Xiang Zhang, Xiaoxiao Yang, Xue Gao, Xiaoshan Du, Xuegan Lian, Naiyuan Shao, Ye Liu, Zhenning Huang, Dongmei Jia, Alexander Y. L. Lau, Zhiguo Li, Zaal Kokaia, Fu‐Dong Shi, Chao Zhang   +13 more
wiley   +1 more source

Toward the Clinical Translation of Implantable Brain–Computer Interfaces for Motor Impairment: Research Trends and Outcome Measures

Advanced Science, EarlyView.
Implantable brain–computer interfaces (iBCIs) are rapidly approaching clinical translation. This review maps key trends in the development of iBCIs and highlights the lack of standardised clinical outcome measures. It discusses a proposed framework for the selection of outcome measures in clinical trials and introduces a new international registry of ...
Esmee Dohle, Eleanor Swanson, Luka Jovanovic, Suraya Yusuf, Lucy Thompson, Hugo Layard Horsfall, William Muirhead, Luke Bashford, Jamie Brannigan   +8 more
wiley   +1 more source

Bibliometric Analysis of Neurosurgery Education From 1962 to 2023 [PDF]

Iranian Journal of Neurosurgery
Background and Aim: Evaluating our scientific trend and patterns in the education of neurosurgery can benefit in determining the needs and the future of the research path, therefore we performed a bibliometric analysis in the Web of Science (WoS) dataset.
Mansour Deylami, Maryam Ziyaei, Roohie Farzaneh, Fateme Maleki, Amin Dalili , Mehrdad Sayadinia, Tayyebeh Zarei , Navid Kalani   +7 more
doaj  

PERIPHERAL NERVE REGENERATION: A Follow-up Study of 3,656 World War II Injuries. Edited by Barnes Woodhall, M.D., Professor of Neurosurgery, Duke University Medical School, Durham, North Carolina; and Gilbert W. Beebe, Ph.D., Statistician, Follow-up Agency Division of Medical Sciences National Research Council. 9x5½ in. Pp. xxiv+67l, with 22 figures, 60 plates and 286 tables. Index. 1956. Washington, D.C.: United States Government Printing Office. Price $3.75 [PDF]

, 1958
Roland Barnes
openalex   +1 more source

Distributed Temporal Coding of Visual Memory Categories in Human Hippocampal Neurons Revealed by an Interpretable Decoding Model

Advanced Science, EarlyView.
This study examines how the human hippocampus encodes visual memory categories. By decoding spiking activity from CA3 and CA1 neurons using an interpretable model, it reveals that category‐specific representations emerge from distributed temporal coding.
Xiwei She, Bryan J. Moore, Brent M. Roeder, George Nune, Brian S. Robinson, Brian Lee, Susan Shaw, Hui Gong, Christianne N. Heck, Gautam Popli, Daniel E. Couture, Adrian W. Laxton, Vasilis Z. Marmarelis, Samuel A. Deadwyler, Charles Liu, Theodore W. Berger, Robert E. Hampson, Dong Song   +17 more
wiley   +1 more source

Comprehensive Characterization of the Immune Microenvironment Based on Nested Resampling Machine Learning Framework Identifies TRAF3 Interacting Protein 3 as a Promising Regulator to Improve the Resistance to Immunotherapy in Glioma

Advanced Science, EarlyView.
This study develops a nested resampling machine learning framework to establish the Immune Glioma Survival Signature (IGLoS), which stratifies glioma patients and predicts immunotherapy resistance. Multi‐omics analyses reveal TRAF3IP3 as a pivotal regulator of PD‐L1 expression and T‐cell exhaustion via ERK‐NFATC2 signaling.
Yanbo Yang, Fei Wang, Yulian Zhang, Run Huang, Chuanpeng Zhang, Lu Zhao, Hanhan Dang, Xinyu Tao, Yue Lu, Dengfeng Lu, Yunsheng Zhang, Kun He, Jiancong Weng, Zhouqing Chen, Zhong Wang, Yanbing Yu   +15 more
wiley   +1 more source

Radiation Exposure Induced Blood–Brain Barrier Injury via Mitochondria‐Mediated Sterile Inflammation

Advanced Science, EarlyView.
This work describes a blood–brain barrier (BBB) microphysiological system (MPS) to explore the responses of BBB to radiation exposure. Following radiation exposure, obvious BBB comprise and brain endothelial injuries are detected. Mechanism study shows radiation induced significant sterile inflammation via mitochondrial dysfunction and cGAS‐STING ...
Peng Wang, Jiayue Liu, Min Zhang, Juan Yang, Peihan Lian, Xiu Cheng, Jianhua Qin   +6 more
wiley   +1 more source

Visualization, navigation, augmentation. The ever-changing perspective of the neurosurgeon

Brain and Spine, 2022
Introduction: The evolution of neurosurgery coincides with the evolution of visualization and navigation. Augmented reality technologies, with their ability to bring digital information into the real environment, have the potential to provide a new ...
A. Boaro, F. Moscolo, A. Feletti, G.M.V. Polizzi, S. Nunes, F. Siddi, M.L.D. Broekman, F. Sala   +7 more
doaj