Results 111 to 120 of about 324,229 (240)
A mouse model of mechanical stress injury to the basal ganglia using thermosensitive PNIPAM hydrogel for intracerebral hemorrhage research
Animal Models and Experimental Medicine, EarlyView.In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...Mingxi Li, Yujie Chen, Rongsu Huang, Min Xia, Chao Mi, Yuan Tian, Peiwen Guo, Taotao Jin, Shilei Hao, Hua Feng, Yujie Chen, Zhi Chen +11 morewiley +1 more sourceNeurosurgical Care in Italy: A Comprehensive Review and Lessons for High-Income Nations. [PDF]
Neurosurg PractHammond A, Paolini L, Sabet CJ, Garg S, Jadav AA, Arkalgud A, Ranganathan S, Kohli K, Jain U, Peruzzi P, Messina R, Umana GE, Ghashghaie G, Shah S, Zhamkochyan A, Mezgebu Bawoke M, Jain B. +16 moreeuropepmc +1 more sourceSpeech Biomarkers for Quantifying Effects of Subthalamic Deep Brain Stimulation in Parkinson's Disease
Annals of Neurology, EarlyView.Objective
Dysarthria is one of the most common and disabling side effects of subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson's disease (PD). Stimulation often exacerbates speech dysfunction beyond the effects of PD progression, likely because of current spread to structures surrounding the STN.Petr Krýže, Mário Sousa, Vojtěch Illner, Adriana Jorge, Matilde Castelli, Ines Debove, Andreia D. Magalhães, Julia Waskönig, Lenard Lachenmayer, Joan Philipp Michelis, Gerd Tinkhauser, Deborah Amstutz, Marie Elise Maradan‐Gachet, Katrin Petermann, Claudio Pollo, Tobias Nef, Paul Krack, Jan Rusz +17 morewiley +1 more sourceAge Is an Effect Modifier of Thrombectomy Benefit in a Socioeconomically Vulnerable Stroke Population
Annals of Neurology, EarlyView.Objective
Randomized trials from high‐income countries have shown that endovascular treatment (EVT) yields similar benefits in elderly and non‐elderly patients with large vessel occlusion stroke (LVOS). However, evidence from low/middle‐income countries remains scarce.Fabricio O. Lima, Francisco José de A. Mont'Alverne, Letícia C. Rebello, Daniel G. Abud, Gisele S. Silva, Michel E. Frudit, Mário B. Wagner, Jamary Oliveira‐Filho, Diogo C. Haussen, David S. Liebeskind, Octávio M. Pontes‐Neto, Norberto A.F. Frota, Guilherme Dabus, Gabriel R. de Freitas, Adson F. de Lucena, Jeffrey L. Saver, Raul G. Nogueira, Sheila C.O. Martins, for the RESILIENT Trial Investigators +18 morewiley +1 more sourceChinese consensus on the diagnosis and treatment of prolactinomas (2025 edition). [PDF]
Chin Neurosurg JLin S, Chen Z, Ji L, Wang L, Zhang W, Tang X, Wu Y, Fan Q, Li J, Pan L, Yao Z, Deng C, Ye H, Li S, Zhu H, Zhao Y, Wang Y, Wu ZB, China Pituitary Adenoma Specialist Council. +18 moreeuropepmc +1 more sourceNeurophysiological Recovery Following Nerve Transfer Surgery to Restore Upper Limb Function after Cervical Spinal Cord Injury
Annals of Neurology, EarlyView.Objectives
Nerve transfer is a promising intervention for restoring hand and upper limb function after cervical spinal cord injury (SCI), but the timeline of neurophysiological recovery in humans remains unclear. This study aimed to define recovery profiles after nerve transfers to restore upper limb function.Kyle J. Missen, Justin M. Brown, Ross M. Mandeville, Harvey Wu, Sean Bristol, Peter K. Broadhurst, Erin Brown, Christopher Doherty, Amy K. Hanlan, Russell O'Connor, Lawrence R. Robinson, Kayton Rotenberg, J. Michael Hendry, Jana Dengler, Michael J. Berger +14 morewiley +1 more sourceMonitoring Antiseizure Medication Change Using Ultra Long‐Term Electroencephalogram: A Multicenter Study
Annals of Neurology, EarlyView.Objective
Medication dose adjustments are common in treatment‐resistant epilepsy, but lack robust evidence, and patient‐reported seizure diaries have known limitations. We assessed whether ultra long‐term subcutaneous electroencephalogram (sqEEG) improves detection of seizure frequency changes after antiseizure medication adjustments.Pedro F. Viana, Matthew McWilliam, Johannes Koren, Christina Duarte, Tamara Lisy, Christoph Baumgartner, Karl Rössler, Matthias Tomschik, Adriana Celdrán de Castro, Rodrigo Rocamora, Laura Vilella, Guido Rubboli, Sigge Weisdorf, Cecilia Friedrichs‐Maeder, Troels W. Kjaer, Sanchita Bhatia, Dympna McAleer, Khalid Hamandi, Deborah Spencer, Rajiv Mohanraj, Mark P. Richardson +20 morewiley +1 more sourceComparison of neuropsychological side effects between contemporary radiofrequency ablative neurosurgery for psychiatric disorders and conventional neurosurgical procedures: systematic review and meta-analysis. [PDF]
J Neurol Neurosurg PsychiatryVilela-Filho O, Bannach MA, Lino-Filho AM, Hamani C, Nuttin B, Hariz M, Schulder M, Greenberg BD, Cosgrove R, De Oliveira-Souza R, Horn A, Sheth SA, Kubu C, Salem S, Zaccariotti AJ, Tavares NO, Damasceno BP, Mayberg HS, Lozano AM, Visser-Vandewalle V, Kuhn J, Falkai P, Slavin K, Doshi P, Lopes AC, Vattimo EF, Coyne T, Akram H, Toda H, Halpern CH, Coenen VA, Gorgulho AA, Andrade P, Blomstedt P, Wu H, Zrinzo L, Sun B, De Quevedo JL, Belmonte-De-Abreu P, Cosyns P, Mclaughlin N, Alkhani A, Giordano J, Berk M, Yatham LN, Chabardes S, Abbadi NE, De Salles AAF, Enslin N, De Sousa MB, Oliveira JO, Labruna R, Reis AM, Jiménez-Ponce F, Ferragut MA, Chang JW, Régis J, Torres CV, Taira T, Lipsman N, Barcia JA, Rezai A, Schuurman R, Martinez-Alvarez R, Dougherty DD, Broggi G, Huys D, Bervoets C, Oliveira PM, Ragazzo PC, Giacobbe P, Lazaro-Munoz G, Polosan M, Naesström M, Johansson V, Schlaepfer T, Ribeiro TM, Lee KH, Neimat JS, Hodaie M, Sitnikov A, Yilmaz A, Almahariq F, Lopez Rios AL, Gonçalves-Ferreira A. +84 moreeuropepmc +1 more sourceNeurotransmitter‐Defined Degeneration Patterns in Sporadic and C9orf72‐Associated Amyotrophic Lateral Sclerosis: Predilection to GABAergic, Serotonergic, Opioid, Glutamatergic, Endocannabinoid, and Microglial Systems—Implications for Therapy Development
Annals of Neurology, EarlyView.Objective
Amyotrophic lateral sclerosis (ALS) has a markedly distinctive clinical and neuroradiological signature, with the preferential involvement of specific brain networks and the apparent sparing of others. The molecular underpinnings of the strikingly selective anatomical vulnerability have not been fully elucidated to date despite the potential ...Marlene Tahedl, We Fong Siah, Jasmin Lope, Jennifer C. Hengeveld, Mark A. Doherty, Russell L. McLaughlin, Orla Hardiman, Ee Ling Tan, Alison Toomey, Jana Kleinerova, Peter Bede +10 morewiley +1 more source
