Results 121 to 130 of about 521,894 (411)

Paraspinal lipoblastoma with multidirectional spread occurring in a pre-school child

Interdisciplinary Neurosurgery, 2019
Lipoblastoma is a rare neoplasm arising from embryonic mesodermal cell rests and occurs most commonly in male infants in the first decade of life.
Paseka Seroto, FC Neurosurgery (SA), Adrian Kelly, MMed Neurosurgery cum laude (SMU), FC Neurosurgery (SA), Tshilidzi Sidiki, MBChB, Aftab Younus, FC Orthopedics (SA)   +3 more
doaj  

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source

Preparation of gastrodin‐modified dendrimer‐entrapped gold nanoparticles as a drug delivery system for cerebral ischemia–reperfusion injury

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Objective This study sought to evaluate the feasibility of multifunctional gastrodin (GAS)‐containing nano‐drug carrier system against cerebral ischemia–reperfusion injury (CIRI). Methods The drug‐loaded nanocomposite (Au‐G5.NHAc‐PS/GAS) with certain encapsulation efficiency (EE) was prepared by physical adsorption method using different ...
Wenqiang Huang, Lanlin Wang, Yanghong Zou, Xiangqian Ding, Xin Geng, Jinghui Li, Hexiang Zhao, Renli Qi, Shipeng Li   +8 more
wiley   +1 more source

A challenging case of an intramedullary dermoid cyst of the cervical spine - A literature review

Interdisciplinary Neurosurgery, 2019
A comprehensive differential diagnosis of intramedullary lesions of the sub-axial cervical spine must begin with the most common namely the diffuse fibrillary astrocytoma.
DrFC Neurosurgery (SA) Patrick Lekgwara, DrMMed Neurosurgery cum laude (SMU), FC Neurosurgery (SA) Adrian Kelly, DrFC Orthopedics (SA) Aftab Younus   +2 more
doaj  

Exploring patient and family satisfaction in pediatric neurological surgery [PDF]

, 2016
Introduction Patient and family satisfaction during outpatient visits is correlated with a continuance of care and likelihood to recommend the practice to others.
Barsoom, Randa R., Burrows, James F., Maugans, Todd A., Rosen, Paul   +3 more
core   +2 more sources

Transcriptomic Profiling Unveils EDN3+ Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis

Advanced Science, EarlyView.
Sturge‐Weber syndrome (SWS) is characterized by leptomeningeal vascular malformations, leading to seizures and stroke. Analysis of 119 446 brain cells from SWS patients uncovered distinct cell heterogeneity and identified an EDN3⁺ meningeal fibroblast cluster, with WNT5A emerging as a potential key driver of SWS progression and a promising therapeutic ...
Daosheng Ai, Tianyue Ming, Xiaoli Li, Shu Wang, Zhanying Bi, Jinyi Zuo, Zizhang Cheng, Weijin Sun, Mingguo Xie, Fengzhi Li, Xiongfei Wang, Xueling Qi, Guoming Luan, Woo‐ping Ge, Yuguang Guan   +14 more
wiley   +1 more source

Clinical outcomes and cognitive impairments between progressive supranuclear palsy and multiple system atrophy

Brain and Behavior, Volume 12, Issue 12, December 2022., 2022
Abstract Background Both progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) belong to atypical parkinsonian syndromes. It is important to differentiate these diseases accurately. We compared clinical outcomes and cognitive impairments between PSP and MSA. Methods Eighty‐five MSA parkinsonism type (MSA‐P) patients and 76 PSP patients
Peifei Jia, Jinhong Zhang, Jiuyan Han, Yong Ji   +3 more
wiley   +1 more source

NF2 is Essential for Human Endoderm Development

Advanced Science, EarlyView.
This study demonstrates that NF2, moesin‐ezrin‐radixin like (MERLIN) tumor suppressor (NF2) is essential for human endoderm formation. NF2 knockout human induced pluripotent stem cells fail to form endoderm both in vitro and in vivo due to yes‐associated protein 1 (YAP1) nuclear translocation, redirecting differentiation toward myofibroblast‐like cells.
Minjin Jeong, Dongjun Han, Preetida Bhetariya, D. Bradley Welling, Miodrag Stojkovic, Konstantina M. Stankovic   +5 more
wiley   +1 more source

17th Annual EMN Congress Cluj-Napoca, Romania

Romanian Neurosurgery, 2012
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Romanian Society of Neurosurgery .
doaj  

Neurocognitive and Seizure Outcomes of Selective Amygdalohippocampectomy versus Anterior Temporal Lobectomy for Mesial Temporal Lobe Epilepsy. [PDF]

, 2014
Objective. To report our institutional seizure and neuropsychological outcomes for a series of patients with mesial temporal lobe epilepsy (mTLE) undergoing anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SelAH) between 2004 and ...
Andrade, Danielle, Carlen, Peter, Cohn, Melanie, Del Campo, Jose M, Fallah, Aria, Mansouri, Alireza, Mayor, Diana, McAndrews, Mary Pat, Tai, Peter, Valiante, Taufik A, Wennberg, Richard A   +10 more
core   +3 more sources