SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease
Advanced Science, EarlyView.SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi +11 more
wiley +1 more source
Promises and Perils of Artificial Intelligence in Neurosurgery.
Neurosurgery, 2019 Artificial intelligence (AI)-facilitated clinical automation is expected to become increasingly prevalent in the near future. AI techniques may permit rapid and detailed analysis of the large quantities of clinical data generated in modern healthcare ...
S. Panesar +5 more
semanticscholar +1 more source
Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling
Advanced Science, EarlyView.A vessel‐on‐a‐chip system is developed to replicate both physiological and pathological vessel cyclic stretches. Proteomic analysis reveals pressure‐overload‐induced vascular remodeling, including cellular response to mechanical cues, cellular oxidative stresses, ER stress, and ceramide biosynthesis activation in the vessel‐on‐a‐chip system, well ...
Yanjun Liu +11 more
wiley +1 more source
The 2nd Congress in the Danube-Carpathian Region. Controversies in neurosurgery
Romanian Neurosurgery, 2012 .
Romanian Society of Neurosurgery .
doaj
ANÆSTHESIA FOR RADIOLOGICAL INVESTIGATIONS IN NEUROSURGERY [PDF]
, 1953 PATRICIA F. de C. COLES
openalex +1 more source
Global neurosurgery: innovators, strategies, and the way forward.
Journal of Neurosurgery, 2019 Around the world today, low- and middle-income countries (LMICs) have not benefited from advancements in neurosurgery; most have minimal or even no neurosurgical capacity in their entire country.
M. Haglund, A. Fuller
semanticscholar +1 more source
Recanalization of the Chronically Occluded Internal Carotid Artery: Review of the Literature. [PDF]
, 2020 Introduction: We reviewed the literature on interventions for patients with medically refractory chronically occluded internal carotid artery (COICA) to assess the risks and/or benefits after recanalization via an endovascular technique (ET) or hybrid ...
Hasan, David M. +4 more
core +1 more source
Virtual and Augmented Reality in Neurosurgery: The Evolution of its Application and Study Designs. [PDF]
, 2022 BACKGROUND: As the art of neurosurgery evolves in the 21st century, more emphasis is placed on minimally invasive techniques, which require technical precision. Simultaneously, the reduction on training hours continues, and teachers of neurosurgery faces
Jean, Walter C, MD
core +1 more source
The Hypoxia‐Associated High‐Risk Cell Subpopulation Distinctly Enhances the Progression of Glioma
Advanced Science, EarlyView.This study suggests the potential roles of a novel hypoxia‐associated CDC20+KIF20A+PTTG1+ cell subpopulation in glioma progression. This high‐risk glioma cell subpopulation is therapeutically vulnerable to glioma progression and may play important roles in glioma standard‐of‐care therapeutic resistance.
Quan Wan +13 more
wiley +1 more source