Results 161 to 170 of about 568,845 (390)

Magnetic Resonance Imaging Reveals Meningeal Lymphatic Impairment in Lung Adenocarcinoma Brain Metastasis Progression

open access: yesAdvanced Science, EarlyView.
This study demonstrates meningeal lymphatic impairment associated with lung adenocarcinoma brain metastasis progression in both human patients and mouse models, establishes clinically applicable non‐invasive imaging biomarkers for quantitative analyzing mLV structure and function, and reveals mLVs as robust prognostic indicators and promising potential
Yuan Zhang   +15 more
wiley   +1 more source

Structure‐Guided Engineering of a Promiscuous O‐Methyltransferase for a SAM Regeneration Biocatalysis Platform of Methylated Pharmaceuticals

open access: yesAdvanced Science, EarlyView.
A substrate promiscuous and regioselective O‐methyltransferase, SmOMT, is functionally and structurally characterized. A double mutant, SmOMTE152A/I306A, exhibited enhanced catalytic activity. By coupling this mutant with a mutant halide methyltransferase, AtHMTV140T, for SAM regeneration, a superior artificial fusion enzyme, AtHMTV140T‐L95‐SmOMTE152A ...
Xiran Xiong   +11 more
wiley   +1 more source

Artificial Intelligence in Neurosurgery: A Bibliometric Analysis.

open access: yesWorld Neurosurgery, 2022
V. G. El-Hajj   +3 more
semanticscholar   +1 more source

Data‐Driven Feedback Identifies Focused Ultrasound Exposure Regimens for Improved Nanotheranostic Targeting of the Brain

open access: yesAdvanced Science, EarlyView.
ABSTRACT The blood‐brain barrier (BBB) renders the delivery of nanomedicine in the brain ineffective and the detection of circulating disease‐related DNA from the brain unreliable. Here, we demonstrate that microbubble‐enhanced focused ultrasound (MB‐FUS) mediated BBB opening, supported by large‐data models predict sonication regimens for safe and ...
Hohyun Lee   +17 more
wiley   +1 more source

Artificial Intelligence in Neurosurgery: Enhancing Diagnosis, Treatment and Patient Outcomes: A Narrative Review

open access: yesJournal of Clinical and Diagnostic Research
Neurosurgery is experiencing the impact of Artificial Intelligence (AI) in the form of improved diagnostic efficiency, procedural dexterity, and postsurgical management.
Chahat Singh   +4 more
doaj   +1 more source

Emergencies during neurosurgery and neuroradiology [PDF]

open access: bronze, 2023
Mohammad Addy, Adriaan C.I.T.L. Tan
openalex   +1 more source

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