Results 41 to 50 of about 6,482 (150)

[Neurosyphilis]. [PDF]

La Revue du praticien, 1977
In patients with abnormal neuropsychiatric symptoms and a reactive fluorescent treponemal antibody absoption (FTA-ABS) test in the cerebrospinal fluid (CSF) or serum, a normal CSF cell count and total protein concentration does not exlude late syphilis involving the central nervous system.
D, Laplane, P, Ricou
openaire   +4 more sources

Treponema pallidum Lipoprotein Tp0768 Induces Proinflammatory Cytokines via TLR4/TLR9‐Mediated MAPK/NF‐κb Pathways in HMC3 Cells

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Neurogenic syphilis is a significant clinical feature of early and late syphilis infections. The disease process triggered by Treponema pallidum is closely related to the activation of the host’s inflammatory response. However, the exact molecular pathways of neuroinflammation caused by Treponema pallidum infection in the central nervous system remain ...
Binfeng Peng, Jirong Luo, Rong He, Jiajun Chen, Shilu Yan, Xiangping Zhou, Ting Cao, Yumeng Li, Xiaopeng Lan, Shuangquan Liu, Arif Jamal Siddiqui   +10 more
wiley   +1 more source

The new progress on diagnosis and treatment of neurosyphilis

Chinese Journal of Contemporary Neurology and Neurosurgery, 2016
Neurosyphilis refers to a chronic infectious disease caused by Treponema pallidum (TP) infection of the central nervous system. The clinical manifestations of neurosyphilis are varied, and the misdiagnosis rate is very high. Particularly when combined
Na WANG, Xin-yue ZHANG, Wu-qiong ZHANG, Wei-guan-liu ZHANG, Li CUI   +4 more
doaj  

Neuroimaging Features, Follow-Up Analyses, and Comparisons Between Asymptomatic and Symptomatic Neurosyphilis

Dermatology and Therapy, 2020
Introduction Many studies have explored the imaging characteristics of patients with neurosyphilis, but no systematic study has been made on the neuroimaging changes after anti-syphilitic treatment.
Xian-Jin Shang, Cai-Feng He, Biao Tang, Xiao-Li Chang, Chao Ci, Hong Sang   +5 more
doaj   +1 more source

Contemporary Clinical Management of Otosyphilis for Practicing Otolaryngologists—A Scoping Review

The Laryngoscope, Volume 135, Issue 12, Page 4490-4498, December 2025.
Otosyphilis has reemerged alongside increasing syphilis rates, highlighting the need for early recognition to prevent severe audiovestibular complications. A scoping review and retrospective case series indicate that most patients present with hearing loss, tinnitus, or vertigo and typically respond to penicillin‐based treatment.
Corinne A. Pittman, Hudson Liu, Sandeep Kowkuntla, Erica Choe, Matthew J. Copeland, Michael Hoa, Selena Briggs, H. Jeffrey Kim   +7 more
wiley   +1 more source

The Value of Oligoclonal Bands in Multiple Sclerosis Compared to Other Neurological Disorders: A Retrospective Data Analysis From an Austrian Tertiary Center

European Journal of Neurology, Volume 32, Issue 12, December 2025.
ABSTRACT Background Cerebrospinal fluid (CSF) analysis is key to diagnosing multiple sclerosis (MS). In particular, the presence of CSF‐specific oligoclonal bands (OCB) is examined alongside differential diagnostic aspects. This study aims to investigate the diagnostic value of OCB in MS compared to other neurological disorders.
Tobias Monschein, Benjamin Scheicher, Markus Ponleitner, Nik Krajnc, Fabian Föttinger, Tobias Zrzavy, Paulus Rommer, Barbara Kornek, Gabriel Bsteh, Thomas Perkmann, Thomas Berger, Fritz Leutmezer   +11 more
wiley   +1 more source

Evaluation of cerebrospinal fluid treponema pallidum particle agglutination assay titer for neurosyphilis diagnosis among HIV-negative syphilis patients

Frontiers in Immunology
PurposeThe study aimed to assess the association between CSF-TPPA titer and the presence of neurosyphilis, and to determine the optimal CSF-TPPA titer cutoff for diagnosing neurosyphilis.MethodsWe conducted a cross-sectional study at a single center from
Mei Shi, Fuquan Long, Danyang Zou, Xin Gu, Liyan Ni, Yuanyuan Cheng, Tengfei Qi, Wei Zhao, Lin Zhu, Zhifang Guan, Pingyu Zhou   +10 more
doaj   +1 more source

Cerebrospinal Fluid Changes and Clinical Features of Neurosyphilis Compared with Latent Syphilis Infection in the Central Nervous System: A Cross-Sectional Study

Infection and Drug Resistance, 2022
Yumei Ge,1,* Xiaoyu Gou,1,* Xiaoyan Dong,1,2 Yumeng Peng,1,3 Fangfang Yang4 1Department of Laboratory Medicine Center, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, 310014, People’s ...
Ge Y, Gou X, Dong X, Peng Y, Yang F
doaj  

Neurosyphilis

Neurology, 1985
Syphilis and its consequent central nervous system sequelae remain clinical problems, especially when presenting in the unfamiliar acute meningeal forms of syphilitic meningitis and meningovascular syphilis. The diagnosis of neurosyphilis of all types depends on evaluation of spinal fluid reactivity as evidenced by pleocytosis and increased protein ...
openaire   +3 more sources

Hyperpigmented Plantar Rash in a Confused Patient With New HIV Diagnosis: Syphilis or Kaposi Sarcoma?

JEADV Clinical Practice, Volume 5, Issue 1, Page 290-291, March 2026.
Claudine Howard‐James, Fei Ya Lai, Stephen Crowther, Maureen Connolly   +3 more
wiley   +1 more source