Results 191 to 200 of about 3,012,382 (313)

NEAT1 Promotes Epileptogenesis in Tuberous Sclerosis Complex

Advanced Science, Volume 13, Issue 1, 5 January 2026.
The primary neurological manifestations of tuberous sclerosis complex (TSC) are intractable epilepsy and intellectual disability. NEAT1 is differentially expressed in TSC‐related epilepsy and influences neuronal excitability by regulating the PI3K/AKT/mTOR signaling pathway.
Suhui Kuang, Tinghong Liu, Zhirong Wei, Jinshan Xu, Jiayi Han, Jiaqi Wang, Feng Zhai, Yiran Tian, Shuli Liang   +8 more
wiley   +1 more source

Genetic and Phenotypic Associations of the Polygenic Score of Delay Discounting and Life History Traits

American Journal of Human Biology, Volume 38, Issue 1, January 2026.
ABSTRACT Objectives Delay discounting reflects individual differences in future orientation and impulsivity and may relate to life‐history strategies. Because delay discounting has a substantial genetic basis, we investigated whether the polygenic score (PGS) for delay discounting is associated with genetic predispositions for key life‐history traits ...
Martin Fieder, Susanne Huber
wiley   +1 more source

Early life adversity and the comorbidity of psychopathology and cardiometabolic disorders: insights from the UK Biobank. [PDF]

BMJ Public Health
Silveira PP, Portella AK, Wang Z, Hoppe JPM, Pokhvisneva I, Meaney MJ.   +5 more
europepmc   +1 more source

Intertemporal Impatience Across Mental Health in a Community Sample: A Novel Transdiagnostic Approach

Journal of Behavioral Decision Making, Volume 39, Issue 1, January 2026.
ABSTRACT Intertemporal impatience has been proposed to be centrally and transdiagnostically implicated across mental health difficulties, including maladaptive behaviors, psychopathologies, and other psychological outcomes. We empirically tested this proposal using a novel research approach that integrates per‐category, trans‐category, scale‐level, and
Floor Burghoorn, Karin Roelofs, William J. Burk, Terrence D. Jorgensen, Anouk Scheres, Bernd Figner   +5 more
wiley   +1 more source

Identifying New Risk Associations Between Chronic Physical Illness and Mental Health Disorders in China: Machine Learning Approach to a Retrospective Population Analysis. [PDF]

JMIR AI
Liang L, Liu T, Ollier W, Peng Y, Lu Y, Che C.   +5 more
europepmc   +1 more source

Deviation From Optimal Physical Activity Duration Worsens Depressive Symptoms Through High Sleep Reactivity and Poor Sleep Quality in Adult Volunteers From the Community

European Journal of Sport Science, Volume 26, Issue 1, January 2026.
ABSTRACT Physical inactivity is considered to increase depressive symptoms. There are also studies reporting that overly strenuous physical activity can negatively affect a person's mental state. Insomnia, which is associated with lower levels of physical activity and increased sleep reactivity, is also known to be associated with depression.
Tomoteru Seki, Akiyoshi Shimura, Kazuki Nakajima, Masayuki Kikkawa, Chihiro Morishita, Yu Tamada, Mina Honyashiki, Jiro Masuya, Takeshi Inoue   +8 more
wiley   +1 more source

Group work for stabilizing psycho-emotional states and preventing neurotic and psychopathic disorders in high school students

Milena Milenina, Alla Topuzova
openalex   +1 more source

Three-way interaction of neuroticism, extraversion, and conscientiousness in the internalizing disorders: Evidence of disorder specificity in a psychiatric sample

, 2017
Kristin Naragon‐Gainey, Leonard J. Simms   +1 more
openalex   +2 more sources

Reduced Serum Soluble L‐Selectin Levels but Not PCSK9 May Be Associated With Generalized Anxiety Disorder: A Case–Control Study

Journal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
The study included 88 generalized anxiety disorder (GAD) patients and 88 age and sex‐matched healthy controls (HCs). A psychiatrist confirmed the GAD diagnosis, assessed symptom severity using the GAD‐7 scale, and evaluated controls based on the DSM‐5 criteria.
Farzana Akter Munny, Abir Hasan Pranto, Shimanta Paul, Md. Aminul Haque, Rashna Sharmin, Sharifa Sultana, Md. Alamgir Hossain, Md. Rabiul Islam   +7 more
wiley   +1 more source

NEUROTIC DISORDER OF CHIELDHOOD [PDF]

The Journal of Nervous and Mental Disease, 1906
openaire   +1 more source