Results 71 to 80 of about 1,668,634 (294)
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen +5 more
wiley +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Exploring assignment-adaptive (ASAD) trading agents in financial market experiments [PDF]
Automated trading systems in the global financial markets are increasingly being deployed to do jobs previously done by skilled human traders: very often a human trader in the markets simply cannot tell whether the counter-party to a trade is another ...
Cliff, Dave +2 more
core +1 more source
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang +14 more
wiley +1 more source
Electric Boolean Games: Redistribution Schemes for Resource-Bounded Agents [PDF]
In Boolean games, agents uniquely control a set of propositional variables, and aim at achieving a goal formula whose realisation might depend on the choices the other agents make with respect to the variables they control.
Wooldridge, M +2 more
core +4 more sources
An Algorithm for Distributing Coalitional Value Calculations among Cooperating Agents [PDF]
The process of forming coalitions of software agents generally requires calculating a value for every possible coalition which indicates how beneficial that coalition would be if it was formed.
Jennings, N. R., Rahwan, Talal
core +2 more sources
Root Apex Transition Zone as Oscillatory Zone
Root apex of higher plants shows very high sensitivity to environmental stimuli. The root cap acts as the most prominent plant sensory organ; sensing diverse physical parameters such as gravity, light, humidity, oxygen and critical inorganic nutrients ...
Frantisek Baluska +2 more
doaj +1 more source
Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Policies for role based agents in environments with changing ontologies [PDF]
10th International Conference on Autonomous Agents and Multiagent Systems 2011, AAMAS 2011 -- 2 May 2011 through 6 May 2011 -- Taipei -- 104775Software agents try to achieve the goals of roles that they have in an environment.
Tekbacak F., Tuglular T., Dikenelli O.
core +2 more sources
Evaluation of the efficacy of potential anesthetic agents on cuttlefish (Sepia pharaonis) juveniles
Anesthesia is often used to relieve stress and reduce mortality rates in aquaculture systems. Here, we assessed the efficacy of four anesthetic agents on cuttlefish (Sepia pharaonis) juveniles. Concentration-response trials were performed to evaluate the
Hua Yang +6 more
doaj +1 more source

