Hyperammonemic stress suppresses ACTA2 expression and induces F‐actin cytoskeletal remodeling in astrocytes. The resulting inhibition of FAK/c‐Src signaling contributes to apoptosis, G2/M arrest, AQP4‐mediated swelling and junction‐associated proteins dysregulation, revealing a central role for ACTA2‐dependent cytoskeletal dysfunction in hepatic ...
Yue Tang +6 more
wiley +1 more source
Maternal and infant gut microbiome
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang +25 more
wiley +1 more source
Does Neuroglobin Protect Against Stroke? Insights Into the Role of Neurovascular Unit Cells. [PDF]
Peinado MÁ +8 more
europepmc +1 more source
Acute Effects of Smoking and Vaping on Markers of Vascular Function via Quantitative MRI
ABSTRACT Background E‐cigarettes contribute to endothelial dysfunction, a known cause of systemic atherosclerotic disease that cannot be adequately characterized by a single physiological parameter measured at a single vascular bed. Purpose/Hypothesis Quantify and compare acute effects of smoking or vaping with tobacco cigarettes (t‐cigs), nicotinized ...
Marianne Nabbout +9 more
wiley +1 more source
Cell- and sex-specificity in the transcriptomic response of the hippocampal neurovascular unit to obesity. [PDF]
Norman JE +3 more
europepmc +1 more source
Sono‐Anatomy and Histology of the Deep Fasciae in the Upper Limb
The deep fascia of the upper limb represents a pivotal anatomical structure essential for effective force transmission, dynamic compartmentalization and musculoskeletal stability. Its composition (rich in type I collagen fibers) enables both mechanical resilience and functional adaptability, crucial for the upper limb's complex movements.
Carmelo Pirri +7 more
wiley +1 more source
The Role of miRNAs in Regulating Neurovascular Unit Homeostasis: Bidirectional Communication and Therapeutic Insights in Ischemic Stroke. [PDF]
Chen H, Gao T, Ma F, Jia Z.
europepmc +1 more source
Abstract Purpose To investigate whether the treatment method of a concomitant lateral meniscus (LM) injury during primary anterior cruciate ligament (ACL) reconstruction (ACLR) affects ACL revision rates in football (soccer) players, nonfootball pivoting athletes and nonpivoting patients differentially, when compared to controls.
Jonas Olsson Wållgren +5 more
wiley +1 more source
Mapping the Neurovascular Unit Genetic Architecture of Early-Onset Ischemic Stroke: A Single-Cell Causal Framework for Target Discovery and Therapeutic Translation. [PDF]
Xu QH, Chai ZH, Zhang YN, Shen J.
europepmc +1 more source
Anatomy of the Lisfranc joint complex: An illustrated review with surgical approach
Abstract This manuscript presents a detailed anatomical review of the Lisfranc joint complex, which includes the tarsometatarsal joints, the intertarsal joints and the proximal intermetatarsal joints. From the bony anatomy to the ligamentous structures reaching the base of the second metatarsal and the surgical anatomy relevant to fix the joint complex,
Xiuqi Liu +5 more
wiley +1 more source

