M2 microglia-derived migrasome-enriched extracellular vesicles restore mitochondrial homeostasis to orchestrate neurovascular unit recovery after ischemic stroke. [PDF]
Zhang Y +15 more
europepmc +1 more source
Why Use Immersive Virtual Reality to Assess Gait in Functional Motor Disorders?
Abstract Background Functional motor disorders (FMD) are disabling conditions modulated by attentional demands. Immersive virtual reality (iVR) engages multiple attentional and sensory networks, but its application in people with FMD (PwFMD) remains limited.
Marialuisa Gandolfi +14 more
wiley +1 more source
A combined extract of <i>Salvia miltiorrhiza</i> and <i>Panax notoginseng</i> enhances collateral flow and protects the neurovascular unit after ischemic stroke. [PDF]
Kwon TW +8 more
europepmc +1 more source
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota +14 more
wiley +1 more source
Bridging regional neurovascular unit heterogeneity and cognitive function: a review. [PDF]
Tsintzou A +6 more
europepmc +1 more source
Abstract Background Magnetic resonance–guided focused ultrasound (MRgFUS) thalamotomy is effective in treating essential tremor (ET) with an adequate safety profile. Objective The aim of the study was to evaluate the real‐world safety and efficacy of staged bilateral MRgFUS thalamotomy in ET and its impact on patient's quality of life (QoL) and patient‐
Dolores Vilas +8 more
wiley +1 more source
Mapping the Neurovascular Unit Genetic Architecture of Early-Onset Ischemic Stroke: A Single-Cell Causal Framework for Target Discovery and Therapeutic Translation. [PDF]
Xu QH, Chai ZH, Zhang YN, Shen J.
europepmc +1 more source
Early Longitudinal Brain Network Changes in Huntington's Disease Before Clinical Motor Onset
Abstract Background Longitudinal studies of seed‐based functional connectivity (SBFC) in young adult Huntington's disease gene‐expanded (HDGE) individuals are rare, and none, to our knowledge, have examined adult cohorts decades from predicted clinical motor diagnosis.
Michela Leocadi +13 more
wiley +1 more source
Disrupted transporter protein expression and cell-specific localization reveal neurovascular unit remodeling in human glioblastoma. [PDF]
Bao X, Jiang Y, Hermes B, Sanai N, Li J.
europepmc +1 more source
Joint Risk Factor Combinations with Additive Interaction Increase the Risk of Parkinson's Disease
Abstract Background Combined effects of multiple risk factors on incident late‐onset Parkinson's disease (PD; LOPD) remain poorly characterized. Objective The objective of this study was to quantify the impact of joint risk exposures and estimate the contribution of potentially modifiable factors to incident LOPD risk.
Andrea Quattrone +5 more
wiley +1 more source

