Results 51 to 60 of about 13,972,114 (292)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Loss comparison of 2 and 3-level inverter topologies
, 2010 This paper investigates semiconductor and DC-link capacitor losses in two two-level and two three-level voltage source inverters. The components of the four inverters are selected to have appropriate voltage and current ratings.
Orfanoudakis, G. +3 more
core +1 more source
A neutral-point potential balance control strategy for three-level inverter based on VSVPWM
Journal of Measurement Science and Instrumentation, 2018 The topology of diode neutral-point-clamped（NPC）three-level inverter is prone to neutral-point potential offset.When the sum of three-phase current is zero,the virtual space vector pulse width modulation（VSVPWM）scheme does not cause the neutral-point ...
CHENG Dong-liang +3 more
doaj
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
, 2012 This paper presents a dc-link voltage ripple compensation method for flying-capacitor (FC)-based active neutral- point-clamped multilevel converters operating under selective harmonic elimination pulsewidth modulation.
Sridhar Pulikanti (20124879) +2 more
core +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
EnergiesWith the increasing penetration of distributed generation, electric vehicles and single-phase loads in the low-voltage distribution network, flexible interconnected systems face more prominent three-phase unbalance and direct-current (DC)-side voltage ...
Yangxin Qiu +6 more
doaj +1 more source