Results 51 to 60 of about 2,942,869 (296)

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

ANALYZER OF QUANTITY AND QUALITY OF THE ELECTRIC POWER

open access: yesВестник Дагестанского государственного технического университета: Технические науки, 2016
One of the activities of the research center for “Energy Saving Technologies and Smart Metering in Electrical Power Engineering" is research work on the use of electronic devices and systems of intelligent power distribution, produced by Analog Devices ...
A. I. Semilyak   +2 more
doaj   +1 more source

Oscillation of Emden–Fowler-Type Neutral Delay Differential Equations

open access: yesAxioms, 2020
In this work, we consider a type of second-order functional differential equations and establish qualitative properties of their solutions. These new results complement and improve a number of results reported in the literature.
Shyam Sundar Santra   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A comparison of neutral landscapes - NK, NKp and NKq

open access: yes, 2002
Recent research in molecular evolution has raised awareness of the importance of selective neutrality. Several different models of neutrality have been proposed based on Kauffman’s well-known NK landscape model.
Geard, N   +4 more
core   +1 more source

Everyday Beliefs About Emotion Perceptually Derived From Neutral Facial Appearance

open access: yesFrontiers in Psychology, 2020
The evolution of the human brain and visual system is widely believed to have been shaped by the need to process and make sense out of expressive information, particularly via the face.
Daniel N. Albohn, Reginald B. Adams
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

THE NEUTRAL CHARACTER OF THE SANCTION OF REVOKING AN ADMINISTRATIVE ACT [PDF]

open access: yesChallenges of the Knowledge Society, 2023
One of the multiple valences of the law state is translated into the fact that any administrative act issued or adopted by the state authorities must meet a series of characteristics that correspond to legal requirements, to be timely, to be issued for ...
Constantin Claudiu ULARIU
doaj  

Regulation of neutral ceramidase in glomerular messangial cells [PDF]

open access: yes, 2009
During the past several years, ceramide has emerged as an important second messenger triggering cell responses including proliferation, differentiation, growth arrest and apoptosis.
Franzen, Rochus
core  

Neutral: a stochastic spatial multispecies model

open access: yes, 2017
C++ code for stochastic spatial neutral/hierarchical models: this is the release v1.0.1, including calculation of multifractal spectra and species clusters sizes and windows compatibility.
Leonardo Saravia (96603)
core   +1 more source

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