Results 61 to 70 of about 5,162,966 (295)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Towards a Non-hierarchical Space of Thought: Reading Roland Barthes’ The Neutral [PDF]
, 2015 The article is devoted to The Neutral: the 1977-1978 lecture course developed and taught by Roland Barthes at the Collège de France. I argue that The Neutral is firmly rooted in the tradition that Brian Massumi defined as “nomad thought” in his ...
Myk, Małgorzata
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Trends in Ecology & Evolution, 2006 Community ecology is in a current state of creative ferment, stimulated by the development of neutral models of community organization. Here, I reflect on recent papers by Scheffer and van Nes, and by Gravel et al., which illuminate how neutrality can emerge from ecological and evolutionary processes, thus suggesting ways to unify neutral and niche ...
Department of Zoology, University of Florida, Gainesville, FL 32605, USA ( host institution ) +1 more
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Radiation-condensation instability in a four-fluid dusty plasma
, 2007 In this work linear stability analysis of a four-fluid optically thin plasma consisting of electrons, ions, neutral atoms, and charged dust particles is performed with respect to the radiation-condensation (RC) instability.
Kopp, A., Shchekinov, Yu. A.
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Fractal and FractionalIn this paper, we present the existence of a mild solution for a class of a neutral stochastic integro-differential system over a Hilbert space. Such systems are influenced by both multiplicative and fractional noise, alongside non-instantaneous impulses,
Hamza Khalil +3 more
doaj +1 more source
Calorimetric detection of neutral-atom content of ion beam [PDF]
, 1974 Energy deposition technique deduces neutral-beam flux or dose from measured values of incremental resistance increases in platinum wire passed through beam. Steady-state heat balance analysis led to equivalent neutral-beam current.
Roberts, A. S., Jr.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source