Results 61 to 70 of about 2,942,869 (296)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Modelling the neutralisation process in neutral beam injectors [PDF]
, 2009 High power neutral beams currently play an important role in heating, fuelling and diagnosing magnetically confined thermonuclear fusion plasmas. At the Joint European Torus (JET) in Oxfordshire, England, the formation of such a beam involves passing a ...
Fitzgerald, Niall J.
core +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
, 2016 Fasta file containing sequences of 535 putatively neutral ...
Cecilia Villacorta-Rath (547601) +17 more
core +1 more source
Collocation schemes for periodic solutions of neutral delay differential equations [PDF]
, 2005 We introduce two collocation schemes for the computation of periodic solutions of neutral delay differential equations (NDDEs): one based on a direct discretisation of the underlying NDDE, and one based on a discretisation of a related delay differential
Wilson, RE +8 more
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Second Biennial Report of the Climate Neutral Working Group [PDF]
, 2007 This second biennial report of the Climate Neutral Working Group (CNWG) is intended to provide a concise update regarding the science of climate change, catalog the ongoing work of the CNWG and synergistic parallel initiatives, and indicate progress made
Climate Neutral Working Group
core
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Periodic solutions to a $p$-Laplacian neutral Duffing equation with variable parameter
Electronic Journal of Qualitative Theory of Differential Equations, 2011 We study a type of $p$-Laplacian neutral Duffing functional differential equation with variable parameter to establish new results on the existence of $T$-periodic solutions.
Bo Du, Bo Sun
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source