Results 81 to 90 of about 5,162,966 (295)

Neutral and Charged Anyon Fluids

, 1993
(Review) Properties of neutral and charged anyon fluids are examined, with the main focus on the question whether or not a charged anyon fluid exhibits a superconductivity at zero and finite temperature.
Hosotani, Yutaka
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Effect of Recombination on the Neutral Evolution of Genetic Robustness

, 2008
Conventional population genetics considers the evolution of a limited number of genotypes corresponding to phenotypes with different fitness. As model phenotypes, in particular RNA secondary structure, have become computationally tractable, however, it ...
Albert, Azevedo, Borenstein, Bornberg-Bauer, Ciliberti, de Visser, Gergely J. Szöllősi, Griffiths-Jones, Hofacker, Huynen, Imre Derényi, Kacser, Kimua, van Nimwegen, Wagner, Wilke, Xia, Zauner   +17 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

A spatio-temporal description of the abrupt changes in the photospheric magnetic and Lorentz-force vectors during the 2011 February 15 X2.2 flare

, 2012
The active region NOAA 11158 produced the first X-class flare of Solar Cycle 24, an X2.2 flare at 01:44 UT on 2011 February 15. Here we analyze SDO/HMI magnetograms covering a 12-hour interval centered at the time of this flare.
A.A. Pevtsov, A.B. Severny, A.G. Kosovichev, A.G. Kosovichev, B. Ravindra, B.C. Low, C. Liu, C. Liu, C.J. Schrijver, D.W. Longcope, G. J. D. Petrie, G.H. Fisher, G.J.D. Petrie, H. Wang, H. Wang, H. Wang, H. Wang, H. Wang, H. Wang, H. Zirin, H.S. Hudson, H.S. Hudson, J. Jing, J. Schou, J. Wang, J.J. Sudol, J.M. Borrero, K.D. Leka, L. Beauregard, L. Fletcher, M. Berger, M.S. Wheatland, N. Deng, P. Venkatakrishnan, S. Gosain, S. Gosain, S. Gosain, S. Inoue, S. Wang, T.R. Metcalf, W.D. Pesnell, X. Sun, Y. Jiang, Y.X. Li   +43 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Human environment and cultural influence on the development of international business [PDF]

Eastern European Journal of Regional Studies, 2017
Peoples always seek to improve their life conditions. This sought had significantly contributed to the improvement of human life. Urbanization was a major turning point in the history of human development.
Nicolae ȚÂU, Mohammedelkhatim IBRAHIM MUSTAFA SHARFELDIN   +1 more
doaj  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Oscillatory behavior of higher-order neutral type dynamic equations

Electronic Journal of Qualitative Theory of Differential Equations, 2013
The oscillation behavior of solutions for higher-order delay dynamic equations of neutral type is investigated by making use of comparison with second-order dynamic equations.
Said Grace, Raziye Mert, Agacik Zafer
doaj   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source