Results 81 to 90 of about 2,998,922 (302)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2012 This article attempts to spell out the main tenets of the principle of state neutrality and to explain how they hang together. It examines the central objections, and explores revisions that may enhance the theory's defensibility. Specifically, it discusses neutrality as non-discrimination, neutrality as shared reasons, objections to liberal neutrality,
openaire +3 more sources
Transport Neutral Digital Object Replication [PDF]
, 2011 Paper for the 2011 Society for Imaging Science and Technology (IS&T) Archiving Conference. This paper discusses a project by the University of North Texas (UNT) Libraries to implement a simple transport neutral digital object replication strategy in its ...
Nordstrom, Kurt, Phillips, Mark Edward
core
Particle acceleration in the presence of weak turbulence at an X-type neutral point [PDF]
, 2012 We simulate the likely noisy situation near a reconnection region by superposing many 2D linear reconnection eigenmodes. The superposition of modes on the steady state X-type magnetic field creates multiple X- and O-type neutral points close to the ...
Petkaki, P. +4 more
core +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Human environment and cultural influence on the development of international business [PDF]
Eastern European Journal of Regional Studies, 2017 Peoples always seek to improve their life conditions. This sought had significantly contributed to the improvement of human life. Urbanization was a major turning point in the history of human development.
Nicolae ȚÂU +1 more
doaj
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
AxiomsThis paper explores the oscillatory behavior of a class of second-order hybrid-type neutral delay difference equations. A novel approach is introduced to transform these complex trinomial equations into a simpler binomial form by utilizing solutions from
Ganesh Purushothaman +3 more
doaj +1 more source