The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo +3 more
wiley +1 more source
Enhanced sensitivity for electron affinity measurements of rare elements. [PDF]
Maier FM +17 more
europepmc +1 more source
PEDOT:PSS—A Key Material for Bioelectronics
PEDOT:PSS ‐ Poly(3,4‐ethylenedioxythiophene) polystyrene sulfonate ‐ is typically processed from water dispersions to form multifunctional and multidimensional constructs with tunable electronic and ionic conductivity. Throught processing engineering, PEDOT:PSS is intergrated in bioelectronic devices that operate efficiently in physiological conditions
Alan Eduardo Ávila Ramírez +5 more
wiley +1 more source
The Hyperacute Phase of Cerebral Infarction in a Swine Model Investigated with Cone-Beam CT Perfusion Imaging. [PDF]
Nagayama G +7 more
europepmc +1 more source
Imperfection in Semiconductors Leading to High Performance Devices
Crystalline perfection is typically pursued in semiconductors to enhance device performance. However, through modeling and experimental work, we show that defects can be strategically employed in a specific detection regime to increase sensitivity to extreme values. GaN diodes are demonstrated to effectively detect high‐energy proton beams at fluxes as
Jean‐Yves Duboz +8 more
wiley +1 more source
HSP60 Mediates NLRP3 Inflammasome-Dependent Microglial Pyroptosis Via the TLR4/MyD88/NF-κB Signaling Axis After Subarachnoid Hemorrhage. [PDF]
Hu ZQ +8 more
europepmc +1 more source
Particle-in-cell simulation of field reversal in mirror trap with neutral beam injection
Y. Tsidulko, I. Chernoshtanov
semanticscholar +1 more source
Ultrathin oxide layer and ultraviolet absorbent are introduced into polyhedral oligomeric silsesquioxane (POSS) polyimide to improve the transmittance conservation and realize near zero mass loss against ultraviolet and atomic oxygen exposures. The POSS polyimide composite sealed triple‐junction GaAs thin‐film solar cell exhibits enhanced endurance of ...
Min Qian +3 more
wiley +1 more source
Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein pre-formed fibrils Parkinson's disease mouse model. [PDF]
Klæstrup IH +8 more
europepmc +1 more source

