Results 51 to 60 of about 79,942 (257)

A class of Neutral Functional Differential Equations

Journal of Differential Equations, 1972
Formulation and study of the initial value problem for neutral functional differential equations. The existence, uniqueness, and continuation of solutions to this problem are investigated, and an analysis is made of the dependence of the solutions on the initial conditions and parameters, resulting in the derivation of a continuous dependence theorem ...
openaire   +2 more sources

Oscillation of Impulsive Neutral Delay Differential Equations

Journal of Mathematical Analysis and Applications, 2002
Here, effective sufficient conditions for the oscillation of all solutions to an impulsive neutral delay differential equation are established. The authors reveal the fact that the oscillatory properties of all solutions to the impulsive equation may be caused by the impulsive perturbations.
Graef, J. R., Shen, J. H., Stavroulakis, I. P.   +2 more
openaire   +3 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

On the behavior of the solutions for certain neutral delay integro-differential equations [PDF]

E-Journal of Analysis and Applied Mathematics
Some results are given on the behavior of solutions of scalar linear and constant coefficient neutral delay integro-differential equations. These results are obtained using two different real roots of the relevant characteristic equation.
Ali Fuat Yeniçerioglu
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Bounded Oscillation of a Forced Nonlinear Neutral Differential Equation

Abstract and Applied Analysis, 2012
This paper is concerned with the nth-order forced nonlinear neutral differential equation [x(t)-p(t)x(τ(t))](n)+∑i=1mqi(t)fi(x(σi1(t)),x(σi2(t)),…,x(σiki(t)))=g(t),  t≥t0.
Zeqing Liu, Yuguang Xu, Shin Min Kang, Young Chel Kwun   +3 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Oscillations of Higher Order Neutral Differential Equations

Rocky Mountain Journal of Mathematics, 1995
Consider linear neutral differential equations of odd order in the form \[ [x(t)- P(t) x(t-\tau)]^{(n)}+ Q(t) x(t-\sigma(t))= 0,\tag{1} \] where \(n\geq 1\), \(\tau> 0\), \(P\), \(Q\), \(\sigma\in C([t_0, \infty),\mathbb{R}^+)\) and \(\lim_{t\to \infty} (t- \sigma(t))= \infty\).
Zhang, B.G., Yu, J.S., Wang, Z.C.
openaire   +3 more sources

Oscillations of higher order neutral differential equations [PDF]

Journal of the Australian Mathematical Society. Series A. Pure Mathematics and Statistics, 1992
AbstractConsider the nth-order neutral differential equation where n ≥ 1, δ = ±1, I, K are initial segments of natural numbers, pi, τi, σk ∈ R and qk ≥ 0 for i ∈ I and k ∈ K. Then a necessary and sufficient condition for the oscillation of all solutions of (E) is that its characteristic equation has no real roots.
Bilchev, S. J., Grammatikopoulos, M. K., Stavroulakis, I. P.   +2 more
openaire   +3 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source