Results 71 to 80 of about 1,965,065 (298)

An Improved Approach to Investigate the Oscillatory Properties of Third-Order Neutral Differential Equations

, 2023
In this work, by considering a third-order differential equation with delay-neutral arguments, we investigate the oscillatory behavior of solutions. It is known that the relationships between the solution and its derivatives of different orders, as well ...
Yousef Alnafisah, Osama Moaaz
core   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Convergence and Divergence of the Solutions of a Neutral Difference Equation [PDF]

Journal of Applied Mathematics, 2011
We investigate the asymptotic behavior of the solutions of a neutral type difference equation of the form Δ[x(n) + cx(τ(n))] + p(n)x(σ(n)) = 0, where τ(n) is a general retarded argument, σ(n) is a general deviated argument (retarded or advanced), c ∈ ℝ, (p(n)) n≥0 is a sequence of positive real numbers such that p(n) ≥ p, p ∈ ℝ+, and Δ denotes the ...
Chatzarakis, G. E., Miliaras, G. N.
openaire   +3 more sources

Homoclinic snaking in a neutral delay model of a transmission line oscillator [PDF]

, 2006
In a transmission line oscillator (TLO) a linear wave travels along a piece of cable, the transmission line, and interacts with terminating electrical components.
Wilson, RE, Barton, DAW, Krauskopf, B
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Functional differential equations of third order

Electronic Journal of Differential Equations, 2005
In this paper, we consider the third-order neutral functional differential equation with distributed deviating arguments. We give sufficient conditions for the oscillatory behavior of this functional differential equation.
Tuncay Candan, Rajbir S. Dahiya
doaj  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Asymptotic Behavior of Solutions of the Third Order Nonlinear Mixed Type Neutral Differential Equations

, 2020
The objective of our paper is to study asymptotic properties of the class of third order neutral differential equations with advanced and delayed arguments. Our results supplement and improve some known results obtained in the literature. An illustrative
Dimplekumar Chalishajar, Osama Moaaz, Omar Bazighifan   +2 more
core   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source