Results 61 to 70 of about 10,137,077 (277)

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Existence of Sobolev-Type Hilfer Fractional Neutral Stochastic Evolution Hemivariational Inequalities and Optimal Controls

Fractal and Fractional, 2023
This article concentrates on a control system with a nonlocal condition that is driven by neutral stochastic evolution hemivariational inequalities (HVIs) of Sobolev-type Hilfer fractional (HF).
Sivajiganesan Sivasankar, Ramalingam Udhayakumar, Venkatesan Muthukumaran, Saradha Madhrubootham, Ghada AlNemer, Ahmed M. Elshenhab   +5 more
doaj   +1 more source

On the approximate controllability for fractional neutral inclusion systems with nonlocal conditions

Fractional Differential Calculus, 2023
Summary: The aim of this work is to study the approximate controllability for some fractional neutral inclusion system with nonlocal conditions. We establish a new variation of constant formula that helps us to formulate the problem of the approximate controllability.
Elghandouri, Mohammed, Ezzinbi, Khalil
openaire   +1 more source

Fractional neutral stochastic integrodifferential equations with Caputo fractional derivative: Rosenblatt process, Poisson jumps and Optimal control

, 2023
The objective of this paper is to investigate the existence of mild solutions and optimal controls for a class of fractional neutral stochastic integrodifferential equations driven by Rosenblatt process and Poisson jumps in Hilbert spaces.
Ravikumar, K., Ramkumar, K., Ahmed, Hamdy   +2 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Approximate Controllability of Higher-Order Hilfer Fractional Neutral Stochastic Systems Driven by Fractional Brownian Motion, Poisson Jumps, and Non-Instantaneous Impulses

Fractal and Fractional
This paper addresses the existence of mild solutions and the approximate controllability of a class of higher-order Hilfer fractional semi-linear neutral stochastic differential equations with non-instantaneous impulses in Hilbert spaces.
A. M. Sayed Ahmed, Taha Radwan, M. Elsaid Ramadan, Hamdy M. Ahmed   +3 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Optimal feedback control for fractional neutral dynamical systems

Optimization, 2018
In this paper, we consider feedback control systems governed by fractional neutral equations involving Riemann–Liouville derivatives. Firstly, we show the existence and uniqueness of solutions for the feedback control systems by applying Krasnoselskiis fixed point theorem.
Liu, Zhenhai, Li, Xuemei, Zeng, Biao
openaire   +2 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Fundamental Matrix, Integral Representation and Stability Analysis of the Solutions of Neutral Fractional Systems with Derivatives in the Riemann—Liouville Sense

Fractal and Fractional
The paper studies a class of nonlinear disturbed neutral linear fractional systems with derivatives in the the Riemann–Liouville sense and distributed delays.
Hristo Kiskinov, Mariyan Milev, Slav Ivanov Cholakov, Andrey Zahariev   +3 more
doaj   +1 more source