Results 81 to 90 of about 2,608,305 (328)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Numerical analysis of negative skin friction on piles in soft clay

open access: yesHBRC Journal, 2013
Negative skin friction is considered one of the problems in the design of piled foundations in soft soil. The negative skin friction induces an additional compressive force on the pile called the dragload as well as, an additional pile movement called ...
Yasser M. El-Mossallamy   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

About the location of some quasipolinomial roots

open access: yesLietuvos Matematikos Rinkinys, 2004
The location of quasipolinomial roots in a complex plane that appear while we investigate differential equations of the locator and the combustion process in the rocket engine is analysed.
Donatas Švitra, Ingrida Sirvydaitė
doaj   +3 more sources

FEM simulation of infeed rotary swaging with structured tools

open access: yesMATEC Web of Conferences, 2015
Rotary swaging is an incremental cold forming process for rods and tubes. Infeed rotary swaging with structure in the reduction zone of the tools is investigated using a two dimensional finite element simulation.
Herrmann Marius   +2 more
doaj   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Study on capacity of single pile subjected to surrounding soil’s settlement

open access: yesTạp chí Khoa học Đại học Mở Thành phố Hồ Chí Minh - Kỹ thuật và Công nghệ, 2012
Piles driven to clay are often subjected to surrounding soil’s settlement due to consolidation and second consolidation of soft soil. Since surrounding soil’s downward movements are larger than piles’s, negative skin friction develop develops on the ...
Võ Phán, Nguyễn Trung Kiên
doaj  

A quantum hydrodynamics approach to the formation of new types of waves in polarized two-dimension systems of charged and neutral particles

open access: yes, 2011
In this paper we explicate a method of quantum hydrodynamics (QHD) for the study of the quantum evolution of a system of polarized particles. Though we focused primarily on the two-dimension physical systems, the method is valid for three-dimension and ...
C. Kittel   +7 more
core   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

open access: yesFEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah   +8 more
wiley   +1 more source

Modal analysis of functionally graded Timoshenko beam

open access: yesVietnam Journal of Mechanics, 2017
Dynamic analysis of FGM Timoshenko beam is formulated in the frequency domain taking into account the actual position of neutral plane. The problem formulation enables to obtain explicit expressions for frequency equation, natural modes and frequency ...
Nguyen Ngoc Huyen, Nguyen Tien Khiem
doaj   +1 more source

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