Results 51 to 60 of about 6,467,658 (289)

Analysing species abundance distribution patterns across sampling scales in three natural forests in Northeastern China

open access: yesiForest - Biogeosciences and Forestry, 2020
Understanding how and why species abundance distributions (SADs) vary with sampling scale has been a long-standing issue in ecology. By fitting various SAD models with observations collected in three large forest field plots, the objective of this study ...
Tan L   +6 more
doaj   +1 more source

The Neutralization Theory of Hatred

open access: yes, 2021
We argue herein that, while often conceptualized as an extreme form of anger, hatred is a human emotion distinct from anger, with unique triggers, conceptual orientations, and terminating conditions. An examination of the social conditions of our species’ evolutionary history reveals that hatred evolved to address its own distinct adaptive problem ...
Aaron Sell   +3 more
openaire   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Phylogenetic Community Structure of Southern African Termites (Isoptera)

open access: yesSociobiology, 2018
The processes that structure communities are still largely unknown. Therefore, we tested whether southern African termite communities show signs of environmental filtering and/or competition along a rainfall gradient in Namibia using phylogenetic ...
Janine Schyra   +2 more
doaj   +1 more source

Neutral theory for competing attention in social networks

open access: yesPhysical Review Research, 2021
Online social networks have significantly changed global communication dynamics. Despite the complexity of such dynamics, emergent patterns from empirical microblogging data on hashtag usage, such as meme popularity power-law distributions, have been ...
Carlos A. Plata   +8 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

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