Results 91 to 100 of about 527,955 (357)
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Network Neutrality and the Evolution of the Internet [PDF]
In order to create incentives for Internet traffic providers not to discriminate with respect to certain applications on the basis of network capacity requirements, the concept of market driven network neutrality is introduced.
Knieps, Günter
core
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Neutrality: A Necessity for Self-Adaptation
, 2002 Self-adaptation is used in all main paradigms of evolutionary computation to increase efficiency. We claim that the basis of self-adaptation is the use of neutrality.
Igel, Christian, Toussaint, Marc
core +5 more sources
Response to comments on "Alfvén 'resonance' reconsidered: Exact equations for wave propagation across a cold inhomogeneous plasma" [PDF]
, 1995 We agree with both Goedbloed and Lifschitz (whom we will refer to as GL) and Ruderman, Goossens and Zhelyazkov (RGZ) that the apparent violation of quasi-neutrality in Ref. 1 is not a true problem and rescind this particular argument against MHD. However,
Bellan, P. M.
core
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
International Evidence on Stochastic and Deterministic Monetary Neutrality. [PDF]
We analyze the issue of the impact of multiple breaks on monetary neutrality results, using a long annual international data set. We empirically verify whether neutrality propositions remain addressable (and if so, whether they hold or not), when unit ...
Antonio E. Noriega +2 more
core
HIGHLIGHTS OF THE SPECIAL ISSUE "CARBON NEUTRALITY AND A LOW CARBON ECONOMY FOR AGRICULTURE" [PDF]
, 2023 Jing Tian, K. W. T. Goulding, Xuejun Liu
openalex +1 more source