Results 71 to 80 of about 527,955 (357)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Temporary Cabinet Foreign Policy: of Non – alignment to Neither West Nor East Principle [PDF]
Faṣlnāmah-i Pizhūhish/hā-yi Rāhburdī-i Siyāsat, 2014 Temporary Cabinet Foreign Policy: of Non – alignment to Neither West Nor East Principle Seyd Hasan Mir Fakhraei* (Received:2014/June/14 – Accept: 2014/Octobr/27) Abstract Foreign policy of the Bazargan cabinet is one of the most controversial ...
seyyed hassan Mirfakhrayi
doaj
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
NETRALITAS POLITIK KIAI DALAM PERSPEKTIF TEORI INTERAKSI SIMBOLIK
Jurnal Dakwah Risalah, 2019 The researcher examines the neutrality of the Kiai in the political year due to the existence of one of the candidates for the vice president who participated in the 2019 election is a great Ulama.
Nurma Yuwita +2 more
doaj +1 more source
SSRN Electronic Journal, 2011 This paper first sets out a framework for understanding network neutrality, by organizing the various issues raised in the course of the network neutrality debate. Secondly, recent US legal and regulatory initiatives are briefly reviewed. Thirdly, the situation under EU law is surveyed.
openaire +3 more sources
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
FEBS Open Bio, EarlyView.Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
The Net Neutrality Debate: Twenty Five Years after United States v. AT&T and 120 Years after the Act to Regulate Commerce [PDF]
Apparent ignorance of more than a century of economic history now threatens the competitive constitution of the Internet under the guise of "net neutrality." Net neutrality is a slogan that stands for the proposition that the Internet and physical means ...
Owen, Bruce M.
core +1 more source
Assessing the Current State of Net Neutrality and Exploring Solutions in Creating and Maintaining Open, Available, and Innovative Internet and Broadband Services [PDF]
, 2019 This article examines the current state of net neutrality regulation in the United States. Debates surrounding net neutrality are varied and layered. They include legal questions regarding how the internet should be classified under existing statutes ...
Troiano, Robbie
core +1 more source
Field induced quantum-Hall ferromagnetism in suspended bilayer graphene [PDF]
, 2012 We have measured the magneto-resistance of freely suspended high-mobility bilayer graphene. For magnetic fields $B>1$ T we observe the opening of a field induced gap at the charge neutrality point characterized by a diverging resistance.
Kurganova, E V +8 more
core +5 more sources