Results 51 to 60 of about 172,495 (309)
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Fundamental Reflections about Austrian Foreign Policy
Управленческое консультирование, 2018 The article represents the first of 30 chapters of the book «Ambition and Reality: Austria’s Foreign Policy since 1945», translated from German into Russian. The book is devoted to the analysis of the foreign policy of Austria since the end of the Second
K. I. Epshteyn-Wessely
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Argumentation et Analyse du Discours, 2016 This article deals with the notion of “neutrality” within the context of Wikipedia. One of the "five pillar" guidance principles for editors on the website is named the "Neutral point of view", reflecting the website’s aspiration to ...
Rivka Dvira
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
IDP, 2011 L'impacte dels avenços tecnològics sobre la xarxa radioelèctrica ha donat lloc a la revisió del model de gestió tradicional de command and control per altres formes de gestió orientades a una eficiència i flexibilitat més grans.
Cristina Cullell March
doaj +1 more source
British Policy and Strategy in the Middle East in 1941: Three Wars ‘East of Suez’
Вестник Московского Университета. Серия XXV: Международные отношения и мировая политика, 2020 After the defeat of France in the summer of 1940, Great Britain was left face to face with the Nazi Germany. It managed to endure the first act of the ‘Battle of Britain’, but could not wage a full-scale war on the continent.
A. M. Fomin
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source