Results 51 to 60 of about 527,955 (357)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Argumentation et Analyse du Discours, 2016 This article deals with the notion of “neutrality” within the context of Wikipedia. One of the "five pillar" guidance principles for editors on the website is named the "Neutral point of view", reflecting the website’s aspiration to ...
Rivka Dvira
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Prophylactic Neutrality, Oppression, and the Reverse Pascal's Wager [PDF]
, 2012 In Beyond Neutrality, George Sher criticises the idea that state neutrality between competing conceptions of the good helps protect society from oppression.
Clarke, Simon R.
core
NILS: a Neutrality-based Iterated Local Search and its application to Flowshop Scheduling [PDF]
, 2011 This paper presents a new methodology that exploits specific characteristics from the fitness landscape. In particular, we are interested in the property of neutrality, that deals with the fact that the same fitness value is assigned to numerous ...
Dhaenens, Clarisse +4 more
core +4 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Revista Română pentru Studii Baltice şi Nordice, 2011 :In the summer of 1915, concerned about Italy's entry into the war in alliance with the Entente powers yet encouraged by the victories of its armies on the Eastern Front, the German diplomacy attempted to encourage Sweden and Romania to abandon their ...
Claudiu-Lucian Topor
doaj
Analiza i Egzystencja, 2016 In this paper I focus on the concept of neutrality taken in the meaning typical for political discussions concerning e.g. the religious neutrality of the state.
Arkadiusz Chrudzimski
doaj +1 more source
HouYi: An open-source large language model specially designed for renewable energy and carbon neutrality field [PDF]
, 2023 Mingliang Bai +8 more
openalex +1 more source