Results 241 to 250 of about 146,246 (308)

SARS-CoV-2 fusion-peptide-directed antibodies are elicited by natural infection and can mediate broad sarbecovirus neutralization. [PDF]

Cell Rep
Roederer AL, Li CJ, Lim E, Cao Y, Ronsard L, Lingwood D, Canaday DH, Gravenstein S, Balazs AB.   +8 more
europepmc   +1 more source

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

Oriented Multivalent Display Drives Consistent Serum Immunodominance to the Ebola Virus Glycoprotein. [PDF]

ACS Cent Sci
Zheng C, Rubio AA, Vasquez S, Pham D, Pan Z, Barnes CO, Kim PS.   +6 more
europepmc   +1 more source

Methods and costs of preventing cadmium emissions. EIR 6636 EN Vol. III. Environment and quality of life [PDF]

, 1980
Rauhut, A.
core  

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

Advanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen, Lian Lou, Xuan Zhang, Lin Yan, Qi Zhang, Wen Shi, Jie Ding, Xu Lin, Rong Jiang, Shuo Liu, Thida Sok, Pengli Wang, Yun Mou, Jie Han, Shenjiang Hu, Xiaogang Guo, Jian Yang   +16 more
wiley   +1 more source

Combination of adenovirus vector and subunit protein elicits a robust immune response against the SARS-CoV-2 Omicron variant. [PDF]

Mol Biomed
Ye C, Huang X, Hong W, Shi J, Ao D, Zhang Y, Lu Y, Zhou Y, Song Z, Zhang Y, Liu Y, Cheng P, Lu G, Li J, Song X, Wei X.   +15 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Protective effect of <i>Prosopis cineraria</i>, <i>Salvadora oleoides</i> and <i>Salvadora persica</i> extracts against <i>Androctonus finitimus</i> envenomation. [PDF]

Toxicon X
Butt SA, Tahir HM, Ahsan MM, Ali A, Muzamil A, Tariq M, Abbas D, Abdel-Maksoud MA, Alamri A, Almutairi S.   +9 more
europepmc   +1 more source

The Role of Ionic Liquids at the Biological Interfaces in Bioelectronics

Advanced Science, EarlyView.
Ionic liquids (ILs) are highlighted as key artificial ionic materials that bridge biological ion‐based signaling and electronic devices. By understanding their composition, structure, function relationships, and mechanisms, ILs can advance from high performance electrolyte to core materials enabling integrated, multifunctional bioelectronics for ...
Yeong‐sinn Ye, Young Jin Jo, Ji Yeon Oh, Ju Yeon Jeong, Lili Guo, Tae‐il Kim   +5 more
wiley   +1 more source

Evaluation of an Effective Intradermal Foot-and-Mouth Disease Vaccine for Early Protection. [PDF]

Vaccines (Basel)
Kim DW, Lee SY, Kim TJ, Kim H, Hwang JH, Park SY, Ko YJ, Lee YH, Park JH, Park SH.   +9 more
europepmc   +1 more source