Results 61 to 70 of about 216,402 (213)

Detection of Antibodies against H5 and H7 strains in Birds: Evaluation of Influenza Pseudovirus Particle Neutralization Tests [PDF]

, 2014
Introduction: Avian influenza viruses circulate in bird populations, and it is important to maintain and uphold our knowledge of the viral strains that are currently of interest in this context.
Lundkvist, Åke,, Karlsson, Malin, Temperton, Nigel J., Lundkvist, Åke, Falk, Kerstin, Leijon, Mikael, Temperton, Nigel J, Lagerqvist, Nina, Cassmer, Michaela, Wallerström, Sofie, Moreno, Ana, Falk, Kerstin I   +11 more
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Fig. 4e: CXCL12-neutralizing

, 2022
Fig. 4e In the co-culture experiment of RHBDD2-CKO HEK293T and U937, pre-treatment with CXCL12-neutralizing antibodies increased cleaved caspase-3-positive cells under cytarabine exposure for 48 h, which was similar to that observed when the cells were ...
Keisuke Sugita (12549460), Morito Kurata (8164626)   +1 more
core   +1 more source

Broadly neutralizing antibodies against Omicron variants of SARS-CoV-2 derived from mRNA-lipid nanoparticle-immunized mice

Heliyon, 2023
The COVID-19 pandemic continues to threaten human health worldwide as new variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerge. Currently, the predominant circulating strains around the world are Omicron variants, which can
Ruei-Min Lu, Kang-Hao Liang, Hsiao-Ling Chiang, Fu-Fei Hsu, Hsiu-Ting Lin, Wan-Yu Chen, Feng-Yi Ke, Monika Kumari, Yu-Chi Chou, Mi-Hua Tao, Yi-Ling Lin, Han-Chung Wu   +11 more
doaj   +1 more source

Development of broadly neutralizing antibodies from autologous neutralizing antibody responses in HIV infection [PDF]

Current Opinion in HIV and AIDS, 2014
Detailed genetic and structural characterization has revealed that broadly neutralizing antibodies (bnAbs) against HIV-1 have unusually high levels of somatic hypermutation, long CDRH3 domains, and the ability to target one of four sites of vulnerability on the HIV-1 envelope (Env) glycoproteins.
Cynthia A, Derdeyn, Penny L, Moore, Lynn, Morris   +2 more
openaire   +2 more sources

Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B. [PDF]

, 2016
Botulinum neurotoxins (BoNTs) are counted among the most toxic substances known and are responsible for human botulism, a life-threatening disease characterized by flaccid muscle paralysis that occurs naturally by food poisoning or colonization of the ...
Frenzel, André, Hust, Michael, Remi Urbain (3080319), Christelle Mazuet, Sebastian Miethe, Robert Tierney, Thibaut Pelat, Michael Hust, Christelle Mazuet (147957), Rasetti-Escargueil, Christine, Alexandre Fontayne (3080307), Arnaud Avril (416869), Pelat, Thibaut, Philippe Thullier, Thullier, Philippe, Yvonne Liu, Michel Robert Popoff (3080316), Mazuet, Christelle, Sesardic, Dorothea, Urbain, Remi, André Frenzel (3080313), Popoff, Michel Robert, Michael Hust (39229), Philippe Thullier (320909), Dorothea Sesardic (803767), Yvonne Liu (803765), Thibaut Pelat (320911), Liu, Yvonne, André Frenzel, Miethe, Sebastian, Alexandre Fontayne, Dorothea Sesardic, Michel Robert Popoff, Remi Urbain, Fontayne, Alexandre, Christine Rasetti-Escargueil, Sebastian Miethe (803763), Robert Tierney (3080310), Christine Rasetti-Escargueil (803764), Tierney, Robert, Avril, Arnaud, Arnaud Avril   +41 more
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Evolution of cross-neutralizing antibody specificities to the CD4-BS and the carbohydrate cloak of the HIV Env in an HIV-1-infected subject. [PDF]

PLoS ONE, 2012
Broadly neutralizing antibodies are considered an important part of a successful HIV vaccine. A better understanding of the factors underlying their development during infection and of the epitopes they target is needed to elicit similar antibody ...
Iliyana Mikell, Leonidas Stamatatos
doaj   +1 more source

Comparison of fluorescent-antibody, neutralizing-antibody, and complement-enhanced neutralizing-antibody assays for detection of serum antibody to respiratory syncytial virus [PDF]

Journal of Clinical Microbiology, 1981
A comparison of three assays for the detection of serum antibody to respiratory syncytial virus (RSV) was carried out on 47 serum samples obtained sequentially from infants and young children with RSV infection. Neutralizing-antibody (NA) activity was determined by a semimicromethod of plaque reduction. Complement-enhanced NA activity was determined by
T N, Kaul, R C, Welliver, P L, Ogra
openaire   +2 more sources

Rapid Quantification of SARS-CoV-2-Neutralizing Antibodies Using Propagation-Defective Vesicular Stomatitis Virus Pseudotypes. [PDF]

, 2020
Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2, a new member of the genus Betacoronavirus, is a pandemic virus, which has caused numerous fatalities, particularly in the elderly and persons with underlying morbidities. At present, there
Meister, Toni Luise, Stephanie Pfaender, Gert Zimmer, Pfaender, Stephanie, Vollmer, Tanja, Steinmann, Jörg, Philip V’kovski, Todt, Daniel, Tanja Vollmer, Daniel Todt, Toni Luise Meister, Adalbert Krawczyk, Zimmer, Gert, Bastian Fischer, Eike Steinmann, Jörg Steinmann, Ferdinand Zettl, Zettl, Ferdinand, Krawczyk, Adalbert, V'kovski, Philip, Fischer, Bastian, Steinmann, Eike   +21 more
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A fine-tuned yeast surface-display/secretion platform enables the rapid discovery of neutralizing antibodies against Clostridioides difficile toxins

Microbial Cell Factories, 2023
Background Neutralizing antibody plays a key role in protecting hosts from invasive pathogens and their virulent components. Current high-throughput assays for antibody screening are based on binding activities.
Ying Sun, Yongrong Zhang, Hua Yu, Ashley Saint Fleur, Di Yu, Zhiyong Yang, Hanping Feng   +6 more
doaj   +1 more source

Antibodies Are Not Essential for the Resolution of Primary Cytomegalovirus Infection but Limit Dissemination of Recurrent Virus [PDF]

, 1994
Virus shedding from the epithelial cells of the serous acini of salivary glands is a major source for the horizontal transmission of cytomegalovirus. These cells are, different to other tissues, exempt from CD8 T lymphocyte control. CD4 T lymphocytes are
Crnkovic, Irena, Koszinowski, Ulrich H., Koszinovski, UH, I Crnković, U H Koszinowski, Pavic, Ivica, S Jonjić, Lucin, Pero, I Pavić, B Polić, P Lucin, Polic, Bojan, Jonjic, Stipan   +12 more
core   +1 more source