Results 161 to 170 of about 289,586 (356)

Filamented Light (FLight) Bioprinting of Mini‐Muscles with Self‐Renewal Potential

open access: yesAdvanced Materials, EarlyView.
This work presents the FLight biofabrication for engineering in vitro muscle constructs by photocrosslinking pristine collagen and fibrinogen using ruthenium. The resulting mini‐muscles retain in vivo‐like tissue organization and a Pax7⁺ cell pool.
Hao Liu   +8 more
wiley   +1 more source

Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift

open access: yesCell Reports
Summary: Developing broad coronavirus vaccines hinges on identifying and understanding the molecular basis of conserved spike epitopes targeted by broadly neutralizing antibodies (bnAbs).
Ge Song   +28 more
doaj  

Optimizing the breadth of SARS-CoV-2-neutralizing antibodies in vivo and in silico

open access: yesHuman Vaccines & Immunotherapeutics
Since the emergence of SARS-CoV-2, the ongoing arms race between mutating viruses and human antibodies has revealed several novel strategies by which antibodies adapt to viral escape. While SARS-CoV-2 viruses exhibit high variability in epitopes targeted
Daisuke Kuroda   +3 more
doaj   +1 more source

The Role of Antibody Bivalence in the Neutralization of Bacteriophage [PDF]

open access: bronze, 1967
Norman R. Klinman   +2 more
openalex   +1 more source

Polyanhydride‐Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single‐Injection Self‐Boosting Vaccines

open access: yesAdvanced Materials, EarlyView.
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang   +17 more
wiley   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

open access: yesAdvanced Materials, EarlyView.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi   +4 more
wiley   +1 more source

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