Results 161 to 170 of about 300,221 (330)

Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses

, 2023
Jay Lubow, Lisa M. Levoir, Duncan Ralph, Laura Belmont, Maya Contreras, Catiana H. Cartwright-Acar, Caroline Kikawa, Shruthi Kannan, Edgar Davidson, Benjamin J. Doranz, Veronica Duran, David ER. Sanchez, Ana M. Sanz, Fernando Rosso, Shirit Einav, F. A. Matsen, Leslie Goo   +16 more
openalex   +1 more source

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

Advanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam, Rabia Ali, Lordean Gustinvil, Matthew J. Rosenwasser, Iain E. Dunlop, Derfogail Delcassian   +5 more
wiley   +1 more source

Fragments of the V1/V2 domain of HIV-1 glycoprotein 120 engineered for improved binding to the broadly neutralizing PG9 antibody

, 2016
Javier F. Morales, Bin Yu, Gerardo Perez, Kathryn A. Mesa, David L. Alexander, Phillip W. Berman   +5 more
openalex   +2 more sources

Neutralizing antibodies in convalescent patients [PDF]

Nature Reviews Immunology, 2020
Uhl, LFK, Chauveau, A
openaire   +3 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

A Pseudo‐Mytilus Edulis Foot Protein‐Based Hydrogel Adhesive with Osteo‐Vascular‐Immune Coupling Effects for Osteoporotic Bone‐Implant Integration

Advanced Materials, EarlyView.
Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's inflammatory environment, it sequentially releases zinc ions and therapeutic peptides: the zinc modulates immune cells to reduce inflammation, while the peptides ...
Wentao Wang, Zhenyu Li, Siming Zhang, Yue Ma, Lei Yu, Qidong Zhang, Guoqing Pan, Dechun Geng, Chen Zhu, Jiaxiang Bai   +9 more
wiley   +1 more source

The 2017 Keystone Symposium on HIV Vaccines

Human Vaccines & Immunotherapeutics, 2017
Christopher A. Cottrell, Andrew B. Ward
doaj   +1 more source

Differential immunity induced by Omicron sublineages in naïve and vaccine breakthrough infections

Scientific Reports
The emergence of the Omicron variant in late 2021 gave rise to multiple descendent lineages, or sublineages, with progressively increased capacity for antibody evasion.
Noah Brazer, Mary Kate Morris, Venice Servellita, Miriam Oseguera, Nanami Sumimoto, Prachi Saldhi, Abiodun Foresythe, Jenny Nguyen, Debra A. Wadford, Carl Hanson, Charles Y. Chiu   +10 more
doaj   +1 more source

Relationships between Neutralization, Binding, and ADCC of Broadly Neutralizing Antibodies against Reservoir HIV

, 2020
Yanqin Ren, Maria Korom, Adam R. Ward, Ronald Truong, Dora Chan, Szu-Han Huang, Colin Kovacs, Erika Benko, Jeffrey T. Safrit, J. Jack Lee, Hermes Garbán, Rebecca M. Lynch, R. Brad Jones   +12 more
openalex   +2 more sources

Rapid, High Throughput, Automated Detection Of SARS-Cov-2 Neutralizing Antibodies Against Native-Like Vaccine And Delta Variant Spike Trimers [PDF]

, 2022
Narayanaiah Cheedarla, Hans Verkerke, Sindhu Potlapalli, Kaleb McLendon, Anamika Patel, Filipp Frank, Gregory L. Damhorst, Huixia Wu, William O’Sick, Daniel S. Graciaa, Fuad Hudaib, David Alter, Jeannette Bryksin, Eric A. Ortlund, Jeannette Guarner, Sara C. Auld, Sarita Shah, Wilbur A. Lam, Dawn Mattoon, Joseph M. Johnson, David H. Wilson, Madhav V. Dhodapkar, Sean R. Stowell, Andrew S. Neish, John D. Roback   +24 more
openalex   +1 more source