Results 161 to 170 of about 1,881,376 (382)

Use of a lambda gt11 expression library to localize a neutralizing antibody-binding site in glycoprotein E2 of Sindbis virus [PDF]

, 1991
The Sindbis virus envelope contains two species of integral membrane glycoproteins, E1 and E2. These proteins form heterodimers, and three dimeric units assemble to form spikes incorporated into the viral surface which play an important role in the ...
Strauss, James H., Wang, Kang-Sheng
core   +1 more source

Self‐Assembling Peptide Hydrogels Support Stromal Vascular Fraction Viability to Promote In Vivo Nerve Regeneration

Advanced Healthcare Materials, EarlyView.
Stromal vascular fraction (SVF) may enhance nerve repair, especially when delivered in a self‐assembling peptide hydrogel (SAPH). In vitro, softer SAPH increased neuronal explant outgrowth and supported greater SVF viability and proliferation. In a rat sciatic defect, SVF in an optimized SAPH produced motor and sensory recovery equivalent to autograft ...
Liam A. McMorrow, Steffan Llewellyn, Jared McSweeney, Alessandro Faroni, Aline F. Miller, Alberto Saiani, Adam J. Reid   +6 more
wiley   +1 more source

Identification of a WSSV neutralizing scFv antibody by phage display technology and in vitro screening [PDF]

, 2006
Yuan Li, Xuan Zhang, Nan Xiao, L.H. Dai, Wen Chen, Chao Jia, Rui Zhao, Sean M. Hemmingsen, Huanqin Dai   +8 more
openalex   +1 more source

Monovalent Omicron COVID-19 vaccine triggers superior neutralizing antibody responses against Omicron subvariants than Delta and Omicron bivalent vaccine

, 2023
Wanting Li, Tiantian Zhao, Tao Bai, Liwei Zhao, Hang Xiao, Xinyu Ding, Chuang Li, Lin Chen, Hao Cheng, Yang Lou, Yuxin Chen, Chao Wu   +11 more
openalex   +1 more source

Detection of antibody-dependent complement mediated inactivation of both autologous and heterologous virus in primary HIV-1 infection [PDF]

, 2005
Specific CD8 T-cell responses to human immunodeficiency virus type 1 (HIV-1) are induced in primary infection and make an important contribution to the control of early viral replication.
Aasa-Chapman, M.M.I., Aubin, K., Borrow, P., Cornforth, D., Holuigue, S., Jones, N.A., McKnight, A., Newton, P., Pellegrino, P., Williams, I., Wong, M.   +10 more
core  

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

Nature, 2021
K. Saunders, Esther Lee, R. Parks, David R. Martinez, Dapeng Li, Haiyan Chen, R. Edwards, S. Gobeil, Maggie Barr, K. Mansouri, S. Alam, Laura L. Sutherland, F. Cai, A. Sanzone, M. Berry, K. Manne, Kevin W. Bock, Mahnaz Minai, Bianca M. Nagata, A. B. Kapingidza, Mihai L. Azoitei, Longping V. Tse, Trevor D. Scobey, Rachel L. Spreng, R. W. Rountree, C. T. DeMarco, T. Denny, C. Woods, Elizabeth W. Petzold, Juanjie Tang, Thomas H. Oguin, G. Sempowski, M. Gagne, D. Douek, M. Tomai, C. Fox, R. Seder, K. Wiehe, D. Weissman, N. Pardi, H. Golding, S. Khurana, P. Acharya, H. Andersen, M. Lewis, Ian N. Moore, D. Montefiori, R. Baric, B. Haynes   +48 more
semanticscholar   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

A human neutralizing antibody targets the receptor-binding site of SARS-CoV-2

Nature, 2020
R. Shi, Chao Shan, Xiaomin Duan, Zhihai Chen, Peipei Liu, Jinwen Song, Tao Song, Xiaoshan Bi, Chao Han, Lian-ao Wu, G. Gao, Xue Hu, Yanan Zhang, Z. Tong, Weijing Huang, William J. Liu, Guizhen Wu, Bo Zhang, Lan Wang, J. Qi, H. Feng, Fu-Sheng Wang, Qihui Wang, G. Gao, Zhiming Yuan, Jinghua Yan   +25 more
semanticscholar   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Deep immunoglobulin repertoire sequencing depicts a comprehensive atlas of spike-specific antibody lineages shared among COVID-19 convalescents

Emerging Microbes and Infections
Neutralizing antibodies are a key component in protective humoral immunity against SARS-CoV-2. Currently, available technologies cannot track epitope-specific antibodies in global antibody repertoires. Thus, the comprehensive repertoire of spike-specific
Qihong Yan, Yudi Zhang, Ruitian Hou, Wenjing Pan, Huan Liang, Xijie Gao, Weiqi Deng, Xiaohan Huang, Linbing Qu, Congli Tang, Ping He, Banghui Liu, Qian Wang, Xinwei Zhao, Zihan Lin, Zhaoming Chen, Pingchao Li, Jian Han, Xiaoli Xiong, Jincun Zhao, Song Li, Xuefeng Niu, Ling Chen   +22 more
doaj   +1 more source