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Fibroblast growth factor 23 neutralizing antibody partially rescues bone loss and increases hematocrit in sickle cell disease mice. [PDF]

Sci Rep
Xiao L, He W, Hurley MM.
europepmc   +1 more source

Longitudinal effects of SARS-CoV-2 breakthrough infection on imprinting of neutralizing antibody responses. [PDF]

EBioMedicine
Einhauser S, Asam C, Weps M, Senninger A, Peterhoff D, Bauernfeind S, Asbach B, Carnell GW, Heeney JL, Wytopil M, Fuchs A, Messmann H, Prelog M, Liese J, Jeske SD, Protzer U, Hoelscher M, Geldmacher C, Überla K, Steininger P, Wagner R, CoVaKo Study group.   +21 more
europepmc   +1 more source

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Production of Neutralizing Antibody

2018
Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika Takemasa, Hitoshi Hasegawa, Shuang Liu   +2 more
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Broadly Neutralizing Antiviral Antibodies

Annual Review of Immunology, 2013
A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive immune response. The widely held view has been that the great variability of viral glycoproteins would be an absolute obstacle to the development of antibody-based therapies or vaccines that could confer broad and long-lasting protection.
Corti D., Lanzavecchia A.
openaire   +3 more sources

Neutralization of HIV by Antibodies

2008
Antibodies can neutralize HIV-1 with potency and cross-reactivity that varies widely and is related but not correlated to their antigen-binding affinity. Therefore, in addition to measuring binding affinity, an evaluation of the antibody neutralizing activity in tissue cultures is important for development of antibody-based therapeutics, design of ...
Ilia Prado, Timothy R. Fouts, Antony S. Dimitrov   +2 more
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Testing for neutralizing antibodies

British Journal of Neuroscience Nursing, 2007
Interferon-beta drugs for multiple sclerosis sometimes give rise to immune proteins that neutralize their effects. Nicola O'Connell and Bronwen Roper look at testing for these neutralizing antibodies
Nicola O'Connell, Bronwen Roper
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Neutralizing antibodies to interferon

Neurology, 2007
The impact of neutralizing antibodies (NAbs) to interferon-beta (IFN-beta) on clinical and imaging parameters in multiple sclerosis (MS) is reviewed. An effect on relapse rates and imaging parameters was noted in patients who tested positive for NAbs, but disability measures were unaffected or showed a trend toward improvement.
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Neutralizing antibody in rodent malaria

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1975
Small numbers of rat erythrocytes infected with viable P. berghei, when inoculated into susceptible rats together with hyperimmune rat serum (HIS), are fully neutralized. Serum from convalescent rats delays the onset of patency but does not neutralize. The neutralizing efficiency of HIS rises in proportion to the number of successive reinoculations of ...
A. Zuckerman, Jacob Golenser, Dan T. Spira   +2 more
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Antibody Neutralization in Hypoprothrombinaemic Plasma

Pathophysiology of Haemostasis and Thrombosis, 1972
The technique of antibody neutralization has been used to study the plasma of a large group of patients with hypoprothrombinaemia of diverse causes. The associated disorders included obstructive jaundice, acute infective hepatitis and chronic parenchymal liver disease. A number of patients were receiving warfarin and salicylate therapy. Irrespective of
P.A. Castaldi, F. Madaras, J.D. Parkin
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