Results 371 to 380 of about 1,804,185 (380)

Production of Neutralizing Antibody

Techniques employing monoclonal antibodies (mAbs) are widely used in the initial development phase of biologics. The usefulness of mAbs in basic RA research has been established based on their characteristics, including specificity of binding, homogeneity, and ability to be produced on a large scale.
Erika, Takemasa, Shuang, Liu
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Statistical issues in neutralizing antibodies

Neurology, 2003
Frequently the question of the effects of neutralizing antibodies (NAbs) is stated, but not clearly. Some ask: “Are we sure NAbs are important?” And others ask: “Are we sure NAbs are NOT important?” These two questions can lead to different statistical designs and different approaches to the investigation of the impact of NAbs.
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Perspectives on the neutralization of interferons by antibody

Neurology, 2003
Interferon (IFN) neutralizing antibody (NAb) interferes with the binding of the IFN molecule to its cellular receptor, thereby preventing receptor activation required to trigger the cascade of signal transduction events that lead to the varied actions of IFN.
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Neutralization by Fragments of Antibody

1993
Experiments to determine whether or not the whole antibody molecule is necessary for neutralization were made possible by digestion with the proteolytic enzymes pepsin, which releases the Fc region leaving an F(ab)2 structure, or papain, which results in a monovalent antigen-binding fragment (Fab). Most data relate to IgG.
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Zika-neutralizing antibodies [PDF]

Nature Immunology, 2017
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HIV-Specific Neutralizing Antibodies

2001
Infection with human immunodeficiency virus type 1 (HIV-1) generates cellular and humoral immune responses of various magnitudes to multiple virus-specific antigens. Perhaps the most beneficial B cell response is one that is directed against the surface gp120 and transmembrane gp41 envelope glycoproteins of the virus; both glycoproteins are major ...
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Neutralizing antibodies revisited [PDF]

Nature Reviews Immunology, 2002
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Neutralization of interferon by specific antibody

Virology, 1962
Kari Cantell, Kari Cantell, Kurt Paucker, Kurt Paucker   +3 more
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Phage Antibodies Neutralize Vaccinia Virus [PDF]

Doklady Biochemistry and Biophysics, 2002
Lev S. Sandakhchiev, Bormotov Ni, Nina V. Tikunova, Batanova Ta, Ovechkina Lg, Alexander A. Ilyichev, E. F. Belanov, V. V. Morozova   +7 more
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Broadly Neutralizing Antibodies

RCSB Protein Data Bank, 2014
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