Results 51 to 60 of about 1,881,376 (382)

HIV broadly neutralizing antibody targets [PDF]

Current Opinion in HIV and AIDS, 2015
To provide an update on neutralizing antibody targets in the context of the recent HIV-1 envelope trimer structure, describe new antibody isolation technologies, and discuss the implications of these data for HIV-1 prevention and therapy.Recent advances in B-cell technologies have dramatically expanded the number of antibodies isolated from HIV ...
Constantinos Kurt, Wibmer, Penny L, Moore, Lynn, Morris   +2 more
openaire   +2 more sources

RSV Neutralizing Antibodies in Dried Blood

The Journal of Infectious Diseases, 2023
Abstract Background The key correlate of protection of respiratory syncytial virus (RSV) vaccines and monoclonal antibodies (mAbs) is virus neutralization, measured via sera obtained through venipuncture.
Jonne Terstappen, Eveline M Delemarre, Anouk Versnel, Joleen T White, Alexandrine Derrien-Colemyn, Tracy J Ruckwardt, Louis J Bont, Natalie I Mazur   +7 more
openaire   +3 more sources

Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals

Msphere, 2021
In this study, we found that neutralizing antibody responses in COVID-19-convalescent individuals vary in magnitude but are durable and correlate well with receptor binding domain (RBD) Ig binding antibody levels compared to other SARS-CoV-2 antigen ...
A. Markmann, Natasa Giallourou, D. Bhowmik, Yixuan J. Hou, A. Lerner, David R. Martinez, L. Premkumar, H. Root, D. van Duin, S. Napravnik, S. Graham, Quique Guerra, R. Raut, C. Petropoulos, T. Wrin, C. Cornaby, J. Schmitz, J. Kuruc, S. Weiss, Yara Park, R. Baric, A. D. de Silva, D. Margolis, L. Bartelt   +23 more
semanticscholar   +1 more source

Interferon-gamma inducible protein 10 (IP10) induced cisplatin resistance of HCC after liver transplantation through ER stress signaling pathway. [PDF]

, 2015
Tumor recurrence remains an obstacle after liver surgery, especially in living donor liver transplantation (LDLT) for patients with hepatocellular carcinoma (HCC).
Geng, Wei, Li, Chang-Xian, Ling, Chang-Chun, Liu, Xiao-Bing, Lo, Chung-Mau, Ma, Yuen-Yuen, Man, Kwan, Ng, Kevin TP, Qi, Xiang, Zhai, Yuan   +9 more
core   +5 more sources

Kinetic Analysis of Monoclonal Antibody Binding to HIV-1 gp120-derived Hyperglycosylated Cores

Bio-Protocol, 2015
Kinetic analysis of antibodies is one of the important studies for characterization of antibodies and screening of ligands. In our recent study (Ingale et al., 2014), we compared the antigenic profiles and binding characteristics of four HIV-1 envelope ...
Jidnyasa Ingale, Richard Wyatt
doaj   +1 more source

HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

Cell Reports, 2020
Summary: Structural and functional studies of HIV envelope glycoprotein (Env) as a transmembrane protein have long been complicated by challenges associated with inherent flexibility of the molecule and the membrane-embedded hydrophobic regions. Here, we
Kimmo Rantalainen, Zachary T. Berndsen, Aleksandar Antanasijevic, Torben Schiffner, Xi Zhang, Wen-Hsin Lee, Jonathan L. Torres, Lei Zhang, Adriana Irimia, Jeffrey Copps, Kenneth H. Zhou, Young D. Kwon, William H. Law, Chaim A. Schramm, Raffaello Verardi, Shelly J. Krebs, Peter D. Kwong, Nicole A. Doria-Rose, Ian A. Wilson, Michael B. Zwick, John R. Yates, III, William R. Schief, Andrew B. Ward   +22 more
doaj   +1 more source

Pre-existing immunity with high neutralizing activity to 2009 pandemic H1N1 influenza virus in Shanghai population. [PDF]

PLoS ONE, 2013
Pre-existing immunity is an important factor countering the pandemic potential of an emerging influenza virus strain. Thus, studying of pre-existing immunity to the 2009 pandemic H1N1 virus (2009 H1N1) will advance our understanding of the pathogenesis ...
Xiaoqing Liu, Yuan Liu, Yanjun Zhang, Zhihui Chen, Ziwei Tang, Qingqiang Xu, Yue Wang, Ping Zhao, Zhongtian Qi   +8 more
doaj   +1 more source

Neutralizing Monoclonal Antibodies Reduce Human Cytomegalovirus Infection and Spread in Developing Placentas. [PDF]

, 2019
Congenital human cytomegalovirus (HCMV) infection is a leading cause of birth defects worldwide, yet the most effective strategies for preventing virus transmission during pregnancy are unknown.
An, Zhiqiang, Fang-Hoover, June, Freed, Daniel C, Fu, Tong-Ming, Li, Fengsheng, Pereira, Lenore, Petitt, Matthew, Tabata, Takako, Wang, Dai   +8 more
core   +1 more source

Neutralizing antiviral antibody responses

, 2001
Neutralizing antibodies are evolutionarily important effectors of immunity against viruses. Their evaluation has revealed a number of basic insights into specificity, rules of reactivity (tolerance), and memory—namely, (1) Specificity of neutralizing antibodies is defined by their capacity to distinguish between virus serotypes; (2) B cell reactivity ...
Zinkernagel, R, LaMarre, A, Ciurea, A, Hunziker, L, Ochsenbein, A, McCoy, K, Fehr, T, Bachmann, M, Kalinke, U, Hengartner, H   +9 more
openaire   +2 more sources

Neutralizing antibodies against coronaviruses [PDF]

Microscopy and Microanalysis, 2021
Neutralizing monoclonal antibodies against SARS-CoV-2 are being used as therapeutics against COVID-19. The Bjorkman laboratory is investigating the mechanisms of virus neutralization by human antibodies that bind the SARSCoV- 2 spike protein. Using structural techniques, including single-particle cryoelectron microscopy and X-ray crystallography, the ...
openaire   +2 more sources