Journal of Clinical Oncology, 2017 Purpose To update a clinical practice guideline (CPG) for the empirical management of fever and neutropenia (FN) in children with cancer and hematopoietic stem-cell transplantation recipients.
T. Lehrnbecher +22 more
semanticscholar +1 more source
Infectious complications in patients with acute leukemia according to the duration of neutropenia
Онкогематология, 2018 Introduction. Patients with hematological malignancies undergoing chemotherapy (CT) have high incidence of infections which profile is affected by various factors including neutropenia.Objective was to evaluate incidence and type of infections in ...
V. A. Okhmat +6 more
doaj +1 more source
Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]
, 2003 Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
core +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Neutropenia presents an important clinical problem in patients with G6PC3 or G6PT deficiency, yet why neutropenia occurs is unclear.
M. Veiga-da-Cunha +10 more
semanticscholar +1 more source
Frequency and Severity of Neutropenia Associated with Food and Drug Administration Approved and Compounded Formulations of Lomustine in Dogs with Cancer. [PDF]
, 2015 BackgroundCompounded lomustine is used commonly in veterinary patients. However, the potential variability in these formulations is unknown and concern exists that compounded formulations of drugs may differ in potency from Food and Drug Administration ...
Burton, JH +5 more
core +2 more sources
Neutropenia in the newborn [PDF]
Current Opinion in Hematology, 2013 The aim is to review normal blood neutrophil concentrations and the clinical approach to neutropenia in the neonatal period. A literature search on neonatal neutropenia was performed using the databases PubMed, EMBASE, and Scopus, and the electronic archive of abstracts presented at the annual meetings of the Pediatric Academic Societies.The review ...
openaire +2 more sources
Faktor Risiko Terjadinya Demam Neutropenia pada Anak Leukemia Limfoblastik Akut
Sari Pediatri, 2016 Latar belakang. Demam neutropenia merupakan suatu sindrom yang terdiri dari dua gejala, yaitu adanya demam dan neutropenia yang didefinisikan sebagai absolute neutrophils count/ANC 0,05) Kesimpulan. Pasien LLA dengan sosial ekonomi rendah berisiko tinggi
MMDEAH Hapsari +2 more
doaj +1 more source
Toxicity Analysis in the ADEBAR Trial: Sequential Anthracycline-Taxane Therapy Compared with FEC120 for the Adjuvant Treatment of High-Risk Breast Cancer [PDF]
, 2012 Background: Data from meta-analyses have shown taxane-containing therapies to be superior to anthracycline-based treatments for high-risk breast cancer. Patients and Methods: The ADEBAR trial was a multicenter phase Ill trial in which patients with lymph
Aivazova-Fuchs, Viktoria +16 more
core +1 more source
Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia.
New England Journal of Medicine, 2007 BACKGROUND Patients with neutropenia resulting from chemotherapy for acute myelogenous leukemia or the myelodysplastic syndrome are at high risk for difficult-to-treat and often fatal invasive fungal infections.
O. Cornely +13 more
semanticscholar +1 more source
Creation and assessment of a clinical predictive calculator and mortality associated with Candida krusei bloodstream infections [PDF]
, 2018 Background Candida krusei bloodstream infection (CK BSI) is associated with high mortality, but whether this is due to underlying comorbidities in affected patients or the organism itself is unknown.
Hsueh, Kevin +4 more
core +2 more sources