Results 41 to 50 of about 156,014 (309)
Serum endocan levels in children with febrile neutropenia
Hematology Reports, 2016 Endocan is an endotelial cell specific molecule; previous studies have shown that serum endocan levels increased in cancer and sepsis and are also related to the severity of sepsis.
Eylem Kiral +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim +11 more
wiley +1 more source
Retrospective analysis of cases with low dose methotrexate-induced neutropenia [PDF]
Objective: Low dosemethotrexate (MTX) is among the most commonly used drugs in rheumatology and rarely associated with neutropenia. It is generally observed as a result of improper use or in patients with risk factors for toxicity.
Elif Dinçses Nas, Sevilay Batıbay
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
BMC CancerBackground Mecapegfilgrastim has been previously validated for efficacy and safety in neutropenia prevention during clinical trials. This nationwide, real-world study (RWS) evaluates its role in protecting against moderate to severe chemotherapy-induced ...
Shukui Qin +22 more
doaj +1 more source
Neutropénia transitória na criança previamente saudável.
Acta Médica Portuguesa, 2001 Transient neutropenia in otherwise healthy children is not unusual, the main causes being infections and drugs. The risk of developing an infectious complication in previously healthy children with transient neutropenia is low.
P Martins, H Pedroso, J G Marques
doaj +1 more source
Cefepime-Induced Neutropenia: A Case Report and Literature Review
, 2023 Somaya Koraysh,1 Junais Koleri,2 Maisa Ali2 1Department of Pharmacy, Hamad Bin Khalifa Medical City, Hamad Medical Corporation, Doha, Qatar; 2Department of Infectious Disease, Communicable Disease Center, Hamad Medical Corporation, Doha ...
Koraysh S, Koleri J, Ali M
core
Arthritis Care &Research, Accepted Article.Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi +10 more
wiley +1 more source