Results 41 to 50 of about 116,210 (265)

Hubungan Antara Parameter Hematologi saat Perawatan Fase Induksi dengan Kejadian Demam Neutropenia pada Anak Leukemia Limfoblastik Akut

Sari Pediatri, 2016
Latar belakang. Demam neutropenia yang terjadi, terutama fase induksi, merupakan keadaan yang mengancam jiwa serta membutuhkan penanganan yang cepat dan segera. Di RSUP Dr. Sardjito, tingkat mortalitas 11% dari 25% insiden demam neutropenia pada Leukemia
Adhitya Putra Pratama, Sunartini Hapsara, Eddy Supriyadi   +2 more
doaj   +1 more source

Quizartinib in Combination With FLAG‐IDA for Relapsed or Refractory Acute Myeloid Leukemia (FLAG‐QUIDA): A PETHEMA Phase I‐II Trial

American Journal of Hematology, EarlyView.
ABSTRACT Quizartinib is a tyrosine kinase inhibitor with single agent activity in patients with relapsed or refractory (R/R) acute myeloid leukemia (AML) and has demonstrated efficacy in first‐line therapy when combined with intensive chemotherapy in both FLT3 ITD‐negative and positive AML.
Teresa Bernal, Javier Zambrano Márquez, Rebeca Rodríguez‐Veiga, Eduardo Rodríguez‐Arbolí, Juan Manuel Bergua‐Burgués, Susana Vives, Montserrat Arnán, Pilar Martínez Sánchez, Pilar Herrera‐Puente, Josefina Serrano‐López, Vicente Rubio, Inmaculada Marchante‐Cepillo, Marta Cervera‐Calvo, Andrés Novo García, Rosa Fernández Martín, Cristina Gil Cortés, Carlos Rodríguez‐Medina, Victor Noriega‐Concepción, Ana Alfonso‐Piérola, Carmen Loredo, María Antuña‐Casal, Blanca Boluda, Isabel Cano‐Ferri, Evelyn Acuña‐Cruz, Laura Torres‐Miñana, Joaquín Sánchez‐García, Cristina Bilbao, Maria Teresa Gómez‐Casares, David Martínez Cuadrón, Pau Montesinos   +29 more
wiley   +1 more source

Congenital neutropenia: diagnosis, molecular bases and patient management

Orphanet Journal of Rare Diseases, 2011
The term congenital neutropenia encompasses a family of neutropenic disorders, both permanent and intermittent, severe (
Chantelot Christine, Beaupain Blandine, Mahlaoui Nizar, Fenneteau Odile, Donadieu Jean   +4 more
doaj   +1 more source

Dordaviprone Maintenance After Allogeneic HCT for High‐Risk Acute Myeloid Leukemia and Myelodysplastic Neoplasm

American Journal of Hematology, EarlyView.
ABSTRACT Dordaviprone is a first‐in‐class small‐molecule imipridone. In preclinical studies, it is active against leukemia cells harboring a TP53 mutation or complex karyotype and leukemia stem cells while sparing normal bone marrow cells. This study aimed to determine the safety of dordaviprone maintenance after allogeneic hematopoietic cell ...
Vijaya Raj Bhatt, Christopher S. Wichman, Alyssa Bouska, Moataz Ellithi, Michael Haddadin, Javeed Iqbal, James E. Talmadge, Lori J. Maness, Krishna Gundabolu   +8 more
wiley   +1 more source

Adjuvant Chemotherapy for Breast Cancer in a Patient with Primary Autoimmune Neutropenia

Breast Cancer: Basic and Clinical Research, 2013
We report an extremely rare and complex case of a 44-year-old woman diagnosed with an early stage triple negative breast cancer in the setting of primary autoimmune neutropenia with a pre-existing severe neutropenia.
Michael Trus, Kavita Dhamanaskar, Jayson Potts, Parveen Wasi, Satvir Bains, Louise Bordeleau   +5 more
doaj   +1 more source

Undetectable Hydroxyurea Levels in the Majority of Sickle Cell Disease Patients, Especially in Young Children

American Journal of Hematology, EarlyView.
ABSTRACT Hydroxyurea (HU) is the most widely prescribed disease‐modifying treatment in sickle cell disease (SCD), though treatment responses vary due to metabolism and adherence. We examined HU blood levels and treatment response in patients with homozygous sickle cell disease (HbSS).
Sigrid van der Veen, Bart J. Biemond, Marjon H. Cnossen, Pablo Bartolucci, Maria P. Boaro, Betzabel Cajiao Garcia, Raffaella Colombatti, M. D'Agnolo, Karin Fijnvandraat, Anna Collado Gimbert, Amira Idrizovic, Petros Kountouris, Mar Mañú‐Pereira, Elisabetta Mezzalira, Mariane de Montalembert, Erfan Nur, A. Pham Hung D' Alexandry D'Orengiani, Tiziana Sanavia, Saskia E. M. Schols, Marissa J. M. Traets, Minke A. E. Rab, Sara I. Reidel, Anita W. Rijneveld, Yosr Zaouali, Nanda M. Verhoeven‐Duif, Judith J. M. Jans, Eduard J. van Beers   +26 more
wiley   +1 more source

Chronic neutropenia in childhood: experience of a tertiary center

Jornal de Pediatria
Objective: To assess the prevalence of chronic neutropenia (CN) and the clinical profile of patients with CN aged up to 18 years, followed in the pediatric hematology, rheumatology, or immunology outpatient clinic of a tertiary medical center from May 1,
Letícia Matushita, Elvis Terci Valera, Davi Casale Aragon, Carlos Alberto Scridelli, Persio Roxo-Junior, Luciana Martins de Carvalho   +5 more
doaj   +1 more source

A multicenter prospective study of 515 febrile neutropenia episodes in Argentina during a 5-year period.

PLoS ONE, 2019
For better management of patients with febrile neutropenia, our study investigated the epidemiologic, microbiologic, and clinical characteristics of adult inpatients with febrile neutropenia and their mortality-associated factors. To this end, we carried
Roberto L Parodi, Mariana Lagrutta, Mauro Tortolo, Estefanía Navall, María S Rodríguez, Gervasio F Sasia, Lucas F De Candia, Matias A Gruvman, Oscar Bottasso, Alcides A Greca   +9 more
doaj   +1 more source

Neutropenia after intravenous immunoglobulin therapy is associated with coronary artery lesions in children with Kawasaki disease: a case control study

BMC Pediatrics, 2018
Background To evaluate differences in laboratory parameters, clinical presentation, and incidence of coronary artery lesions (CAL) between children with neutropenic and non-neutropenic Kawasaki disease (KD).
Zhenquan Wang, Fengfeng Weng, Chen Li, Hongying Shi, Zhangke Tang, Huixian Qiu, Yue’e He, Rongzhou Wu, Maoping Chu   +8 more
doaj   +1 more source

Neutropenia

Canadian Medical Association Journal, 2022
Mithoowani, Siraj, Cameron, Lita, Crowther, Mark A.   +2 more
openaire   +2 more sources