Results 51 to 60 of about 156,014 (309)

Computed tomography-derived sarcopenia, enteral nutritional support, and febrile neutropenia burden in children with acute lymphoblastic leukemia: a retrospective cohort study

Frontiers in Pediatrics
ObjectiveThis study aimed to evaluate computed tomography-derived sarcopenia and enteral nutritional support in relation to febrile neutropenia burden, hospital stay, and mortality in children receiving treatment for acute lymphoblastic leukemia ...
Şule Çalışkan Kamış, Burak Kamış, Metin Çil, Nihal Boz, Ayşe Selcan Koç, Begül Yağcı   +5 more
doaj   +1 more source

Update Management of Chemotherapy-Induced Neutropenia: A Narrative Literature Review [PDF]

, 2023
One of the most frequent and significant complicated side effects of myelosuppressive drugs is neutropenia. Neutropenia is not only associated with high morbidity but also mortality.
Norman Djamaluddin, Mediarty Syahrir, Adriani, Mita, Yenny Dian Andayani, Mita Adriani, null Norman Djamaluddin, null Mediarty Syahrir, null Yenny Dian Andayani   +7 more
core   +1 more source

Real‐World Effectiveness and Safety of Secukinumab in Giant Cell Arteritis: An Italian Multicenter Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in patients with giant cell arteritis (GCA). Methods This multicenter retrospective study included patients with GCA who received secukinumab at 14 Italian centers with at least six months of follow‐up.
Luca Iorio, Federica Davanzo, Caterina Ricordi, Milena Bond, Ruggiero Mascolo, Jacopo Mora, Alessandro Tomelleri, Angelo Fassio, Francesca Cuzzocrea, Sara Monti, Edoardo Conticini, Fabiola Atzeni, Paolo Delvino, Carlotta Nannini, Augusta Ortolan, Francesco Pollastri, Ester Vivaldelli, Chiara Marvisi, Paola Toniati, Antonio Brucato, Alessandra Milanesi, Francesca Regola, Enrico Tombetti, Lorenzo Dagna, Roberta Ramonda, Christian Dejaco, Luca Quartuccio, Carlo Salvarani, Roberto Padoan   +28 more
wiley   +1 more source

Impact of Neutropenia on Clinical Outcomes in Critically Ill Patients with Acute Respiratory Failure

Pulmonary Therapy
Introduction Neutropenia is a common clinical condition in critically ill patients and may be associated with poor outcomes, particularly in the context of acute respiratory failure (ARF).
Hwan Il Kim, Seong Mi Moon, Hyo Seok Oh, Ryoung-Eun Ko   +3 more
doaj   +1 more source

Neutropenia in Childhood—A Narrative Review and Practical Diagnostic Approach

Hematology Reports
Neutropenia refers to a decrease in the absolute neutrophil count according to age and race norms and poses a common concern in pediatric practice. Neutrophils serve as host defenders and act crucially in acute inflammation procedures.
Georgios Katsaras, Silouani Koutsi, Evdokia Psaroulaki, Dimitra Gouni, Pelagia Tsitsani   +4 more
doaj   +1 more source

Hubungan Antara Parameter Hematologi saat Perawatan Fase Induksi dengan Kejadian Demam Neutropenia pada Anak Leukemia Limfoblastik Akut

Sari Pediatri, 2016
Latar belakang. Demam neutropenia yang terjadi, terutama fase induksi, merupakan keadaan yang mengancam jiwa serta membutuhkan penanganan yang cepat dan segera. Di RSUP Dr. Sardjito, tingkat mortalitas 11% dari 25% insiden demam neutropenia pada Leukemia
Adhitya Putra Pratama, Sunartini Hapsara, Eddy Supriyadi   +2 more
doaj   +1 more source

Incidence of Severe Chronic Neutropenia in South Korea and Related Clinical Manifestations: A National Health Insurance Database Study

Medicina, 2020
Background and objectives: Severe chronic neutropenia (SCN) is a condition in which absolute neutrophil counts remain at a low level (under 500/µL) over months or years.
Nuri Lee, Boung Chul Lee
doaj   +1 more source

Cytopenias following anti-CD19 chimeric antigen receptor (CAR) T cell therapy: a systematic analysis for contributing factors

Annals of Medicine, 2022
Background Cytopenia is one of the most common adverse events following the CAR-T cell infusion, affecting the quality of life and potentially leading to life-threatening bleeding and infection.
Yuan Xia, Jue Zhang, Jing Li, Lina Zhang, Jianyong Li, Lei Fan, Lijuan Chen   +6 more
doaj   +1 more source

CXCL3 Antagonism Reverses Systemic Antitumor Immune Memory Impairment Associated With High Tumor Burden and Sensitizes Anti‐PD‐1 Therapy

Advanced Science, EarlyView.
This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang, Xinyu Tang, Zeju Li, Qi Qi, Chang Sun, Wen Sun, Weiya Zhang, Yue Yin, Ya Deng, Peiwen Ling, Yifan Xu, Guangshun Sun, Yi Ren, Hong Pan, Shui Wang, Wenbin Zhou   +15 more
wiley   +1 more source

Congenital neutropenia: diagnosis, molecular bases and patient management

Orphanet Journal of Rare Diseases, 2011
The term congenital neutropenia encompasses a family of neutropenic disorders, both permanent and intermittent, severe (
Chantelot Christine, Beaupain Blandine, Mahlaoui Nizar, Fenneteau Odile, Donadieu Jean   +4 more
doaj   +1 more source