Clinical manifestations and outcomes of pediatric chronic neutropenia
Neutropenia is a decrease in the number of circulating neutrophils. When neutropenia persists for more than 3 months, it becomes chronic. A heterogeneous group of diseases in children can cause chronic neutropenia.
Chuan Wan +7 more
doaj +1 more source
Association between radioactive iodine uptake and neutropenia in untreated Graves’ disease
Objective: Neutropenia is a complication of Graves' disease (GD), but there is currently no means by which to predict its occurrence. This study aimed to investigate the risk factors for the development of neutropenia in untreated GD. Methods: This was
Qian Yang +5 more
doaj +1 more source
Abemaciclib in Combination with Single-Agent Options in Patients with Stage IV Non–Small Cell Lung Cancer: A Phase Ib Study [PDF]
Purpose: Abemaciclib, a dual inhibitor of cyclin-dependent kinases 4 and 6, has demonstrated preclinical activity in non–small cell lung cancer (NSCLC).
Beckmann, Richard +16 more
core +2 more sources
Pulse-Administered Toceranib Phosphate Plus Lomustine for Treatment of Unresectable Mast Cell Tumors in Dogs. [PDF]
BackgroundNonresectable mast cell tumors (MCT) in dogs remain a therapeutic challenge, and investigation of novel combination therapies is warranted. Intermittent administration of tyrosine kinase inhibitors (TKI) combined with cytotoxic chemotherapy may
Avery, AC +7 more
core +1 more source
Costs associated with febrile neutropenia in solid tumor and lymphoma patients - an observational study in Singapore. [PDF]
BackgroundThe primary objective was to describe the total direct inpatient costs among solid tumor and lymphoma patients with chemotherapy-induced febrile neutropenia (FN) and the factors that were associated with higher direct cost.
A Bosly +24 more
core +2 more sources
Metronomic chemotherapy preserves quality of life ensuring efficacy in elderly advanced non small cell lung cancer patients [PDF]
Metastatic non small cell lung cancers (NSCLC) are diseases with poor prognosis and platinum-based doublet chemotherapy still remains their standard cure.
DE IULIIS, Francesca +5 more
core +1 more source
Clinical spectrum of pediatric neutropenia: mostly benign, but not to be overlooked
Background. Neutropenia is a common laboratory finding in children, therefore it is a common referral reason to pediatric hematology units. This study hypothesizes that most neutropenic children do not require pediatric hematology consultation, and that
Şefika Akyol +3 more
doaj +1 more source
Predictive value of hematological and phenotypical parameters on postchemotherapy leukocyte recovery [PDF]
Background: Grade IV chemotherapy toxicity is defined as absolute neutrophil count <500/μL. The nadir is considered as the lowest neutrophil number following chemotherapy, and generally is not expected before the 7th day from the start of chemotherapy.
Abbasciano V +15 more
core +1 more source
We conducted open label, non-comparative trial in patients aged > 60 with advanced and intermediate-grade NonHodgkin Lymphoma (NHL) (stadium II, III, IV) to evaluate the efficacy and safety of In-Asia-manufactured rhG-CSF 300 mcg for prevention of CHOP (
Harryanto Reksodiputro +15 more
doaj +1 more source
Cabazitaxel in the treatment of metastatic castration-resistant prostate cancer: patient selection and special considerations. [PDF]
Cabazitaxel is an effective chemotherapeutic agent used in the treatment of metastatic castration-resistant prostate cancer (mCRPC) refractory to docetaxel.
Hoffman-Censits, Jean, Patel, Sheel
core +3 more sources

