Results 301 to 310 of about 50,090 (336)

Post-COVID pulmonary injury in K18-hACE2 mice shows persistent neutrophils and neutrophil extracellular trap formation. [PDF]

Immun Inflamm Dis
Giannakopoulos S, Park J, Pak J, Tallquist MD, Verma S.   +4 more
europepmc   +1 more source

PI3Kγ promotes neutrophil extracellular trap formation by noncanonical pyroptosis in abdominal aortic aneurysm. [PDF]

JCI Insight
Xiong Y, Liu S, Liu Y, Zhao J, Sun J, Li Y, Pan B, Wang W.   +7 more
europepmc   +1 more source

Erratum to "Inhibition of ALOX12-12-HETE Alleviates Lung Ischemia-Reperfusion Injury by Reducing Endothelial Ferroptosis-Mediated Neutrophil Extracellular Trap Formation". [PDF]

Research (Wash D C)
Li C, Gao P, Zhuang F, Wang T, Wang Z, Wu G, Zhou Z, Xie H, Xie D, Zhao D, Wu J, Chen C.   +11 more
europepmc   +1 more source

Down-regulation of SHP2 promotes neutrophil autophagy and inhibits neutrophil extracellular trap formation to alleviate asthma through the ERK5 pathway. [PDF]

Cent Eur J Immunol
Shi D, Huang J, Wu J.
europepmc   +1 more source

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Dysregulated neutrophil extracellular traps formation in sepsis

Immunology, 2023
AbstractThe migration and antimicrobial functions of neutrophils seem to be impaired during sepsis and contribute to the dysregulation of immune responses and disease pathogenesis. However, the role of neutrophil extracellular traps (NETs) remains to be clarified.
Maria Mulet, Ruben Osuna‐Gómez, Carlos Zamora, Iris Artesero, Marc Arús, Paula Vera‐Artazcoz, Alejandra Cordón, Noelia Vilalta, Paula San‐José, Andrés Abril, Antoni Moliné, Indalecio Morán, Joaquín López‐Contreras, Silvia Vidal   +13 more
openaire   +2 more sources

Autophagy Primes Neutrophils for Neutrophil Extracellular Trap Formation during Sepsis

American Journal of Respiratory and Critical Care Medicine, 2017
Neutrophils are key effectors in the host's immune response to sepsis. Excessive stimulation or dysregulated neutrophil functions are believed to be responsible for sepsis pathogenesis. However, the mechanisms regulating functional plasticity of neutrophils during sepsis have not been fully determined.We investigated the role of autophagy in neutrophil
S. Park, Sanjeeb Shrestha, Young-Jin Youn, Jun-Kyu Kim, Shin-Yeong Kim, Hyun Jung Kim, Sohee Park, Won-Gyun Ahn, Shin Kim, M. Lee, K. Jung, Y. Park, E. Mo, Y. Ko, S. Lee, Y. Koh, M. Park, D. Song, C. Hong   +18 more
semanticscholar   +4 more sources

Mechanical Ventilation Induces Neutrophil Extracellular Trap Formation

Anesthesiology, 2015
AbstractAbstract By creating lung injury in mice using intratracheal lipopolysaccharide and mechanical ventilation, the authors documented that neutrophil extracellular traps were formed when lipopolysaccharide was present during high tidal ventilation and could be treated with deoxyribonuclease I.
Christopher, Yildiz, Nades, Palaniyar, Gail, Otulakowski, Meraj A, Khan, Martin, Post, Wolfgang M, Kuebler, Keith, Tanswell, Rosetta, Belcastro, Azhar, Masood, Doreen, Engelberts, Brian P, Kavanagh   +10 more
openaire   +2 more sources

Pyroptosis Mediates Neutrophil Extracellular Trap Formation during Bacterial Infection in Zebrafish

Journal of Immunology, 2021
Key Points Zebrafish caspy2–GSDMEb axis contributes to neutrophil pyroptosis in vivo. Depletion of caspy2 or GSDMEb impairs the process of NETosis. Pyroptosis-gated NETosis plays a critical role in teleost innate immunity.
Weijie Chen, Jingjing Zhao, Di Mu, Zhuang Wang, Qin Liu, Yuanxing Zhang, Dahai Yang   +6 more
semanticscholar   +1 more source

Role of PTEN in neutrophil extracellular trap formation

Molecular Immunology, 2015
NETosis has been associated with a particular mode of cell death although it is still controversial as to what extent autophagy is involved in NETosis. Class I/AKT/mTOR pathway is a key regulator of autophagy. PTEN tumor suppressor gene encodes a dual specificity phosphatase that antagonizes the phosphatidylinositol 3-kinase in class the I/AKT/mTOR ...
Shahram, Teimourian, Ehsan, Moghanloo
openaire   +2 more sources

Enhanced formation of neutrophil extracellular traps in Kawasaki disease

Pediatric Research, 2020
Neutrophils contribute to the clearance of pathogens through the formation of neutrophil extracellular traps (NETs) in a process known as NETosis, but the excessive release of NETs has been reported to be involved in the pathogenesis of various diseases, including vasculitis, by inducing tissue injury.
Yusuke Yoshida, Seiichiro Takeshita, Yoichi Kawamura, Takashi Kanai, Yuki Tsujita, Shigeaki Nonoyama   +5 more
openaire   +2 more sources