Does NETosis Contribute to the Bacterial Pathoadaptation in Cystic Fibrosis? [PDF]
Significant advances in our understanding of neutrophil biology were made in the past several years. The exciting discovery that neutrophils deploy neutrophil extracellular traps (NETs) to catch pathogens paved the way for a series of additional studies ...
Gadjeva, Mihaela, Rahman, Samir
core +1 more source
Neutrophil Extracellular Traps and DNases Orchestrate Formation of Peritoneal Adhesions
Peritoneal adhesions are poorly understood but highly prevalent conditions that can cause intestinal obstruction and pelvic pain requiring surgery. While there is consensus that stress-induced inflammation triggers peritoneal adhesions, the molecular processes of their formation still remain elusive.
Julia Elrod +22 more
openaire +3 more sources
Severe COVID-19 is characterized by an increase in the number and changes in the function of innate immune cells including neutrophils. However, it is not known how the metabolome of immune cells changes in patients with COVID-19.
Yafeng Li +8 more
doaj +1 more source
Neutrophil extracellular traps as innate immune reaction against the emerging apicomplexan parasite Besnoitia besnoiti [PDF]
Besnoitia besnoiti infection in cattle is an important emerging protozoan disease in Europe causing economic losses and severe clinical signs, such as generalized dermatitis, orchitis, and vulvitis in affected animals. Neutrophil extracellular trap (NET)
Cortes, Helder +4 more
core +2 more sources
Neutrophil Extracellular Traps Drive Kidney Stone Formation
Introduction: This study aims to explore the contribution of neutrophil extracellular traps (NETs) to kidney stones. Methods: The microarray data from GSE73680 and bioinformatic analysis were applied to identify differentially expressed genes in patients with kidney stones.
Zhiming Yang +5 more
openaire +3 more sources
Mechanisms and disease relevance of neutrophil extracellular trap formation [PDF]
AbstractWhile the microscopic appearance of neutrophil extracellular traps (NETs) has fascinated basic researchers since its discovery, the (patho)physiological mechanisms triggering NET release, the disease relevance and clinical translatability of this unconventional cellular mechanism remained poorly understood.
Kristof Van Avondt, Dominik Hartl
openaire +2 more sources
IgA Complexes Induce Neutrophil Extracellular Trap Formation More Potently Than IgG Complexes
Neutrophil extracellular trap (NET) formation is a powerful instrument to fight pathogens, but may induce collateral damage in the affected tissues. Besides pathogen-derived factors, immune complexes are potent inducers of NET formation.
Anna-Katharina Gimpel +10 more
doaj +1 more source
Pauci-immune glomerulonephritis in individuals with disease associated with levamisole-adulterated cocaine: a series of 4 cases. [PDF]
Exposure to levamisole-adulterated cocaine can induce a distinct clinical syndrome characterized by retiform purpura and/or agranulocytosis accompanied by an unusual constellation of serologic abnormalities including antiphospholipid antibodies, lupus ...
Butcher, Brad +6 more
core +2 more sources
Regulation of Neutrophil Extracellular Trap Formation by Anti-Inflammatory Drugs [PDF]
The formation of neutrophil extracellular traps (NETs) is a newly described phenomenon that increases the bacteria-killing ability and the inflammatory response of neutrophils. Because NET generation occurs in an inflammatory microenvironment, we examined its regulation by anti-inflammatory drugs.
Lapponi, María José +7 more
openaire +3 more sources
Hyperferritinemic syndrome is a collective term for a group of severe inflammatory conditions distinguished by high ferritin levels, including adult-onset Still’s disease and COVID-19.
Jinchao Jia +24 more
doaj +1 more source

