Results 1 to 10 of about 17,831 (222)

Mineralocorticoid receptor activation contributes to intestinal fibrosis through neutrophil gelatinase-associated lipocalin in preclinical models [PDF]

Nature Communications
Intestinal fibrosis is a common complication in inflammatory bowel diseases with no specific therapy. Because mineralocorticoid receptor antagonism prevented inflammation and fibrosis in extra-intestinal organs, we aimed to evaluate mineralocorticoid ...
Asma Amamou, Mathilde Leboutte, Jonathan Breton, David Ribet, Pierre-Alain Thiebaut, Christine Bôle-Feysot, Charlène Guérin, Kanhia Aublé, Elise Rebollo, Lise Ratel, Benjamin Bonnard, Alexis Goichon, Louison Leblond, Moutaz Aziz, Elodie Fermant, Frédéric Jaisser, Guillaume Savoye, Rachel Marion-Letellier   +17 more
doaj   +3 more sources

NGAL: An Upcoming Biomarker of Interest [PDF]

Indian Journal of Medical Biochemistry, 2023
Aim: Neutrophil gelatinase-associated lipocalin (NGAL) performs important functions in the body. It has the potential to act as a diagnostic and prognostic biomarker for various diseases.
Khushboo Jasotani, Kiran Dahiya, Raunak Ahlawat, Mohit Gupta, Sushil Kumar, Rakesh Dhankhar, Pragati Singh   +6 more
doaj   +1 more source

Neutrophil Gelatinase-Associated Lipocalin Level Can Predict Early Organ Damage in Primary Hypertensive Patients: A Pilot Study

Anatolian Journal of Cardiology, 2023
Background: Early detection and treatment of complicated arterial hypertension will prevent its effect on the target organs. In line with this purpose, we aimed to reveal the prediction capability of neutrophil gelatinase-associated lipocalin to ...
Serdar Gökhan Nurkoç, Serkan Ünlü, Bayram Şen, Atike Burçin Tefon, Murat Hasanreisoglu, Asife Şahinarslan   +5 more
doaj   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

Hepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino, Salvatore Piano, Matteo Stenico, Marta Tonon, Alessandra Brocca, Valeria Calvino, Simone Incicco, Nicola Zeni, Roberta Gagliardi, Chiara Cosma, Martina Zaninotto, Patrizia Burra, Umberto Cillo, Daniela Basso, Paolo Angeli   +14 more
wiley   +1 more source

Role of Neutrophil Gelatinase-Associated Lipocalin for Early Detection of Acute Kidney Linjury Before and After Cardiac Catheterization

Advanced Medical Journal, 2023
Background and objectives:Acute kidney injury develops in up to 5% of the hospitalized patients and in up to 30% patients admitted in the Intensive Care Unit.
Zana Sidiq Mohammed Saleem, Safa Ezzidin Al-Mukhtar, Kais Hasan Abd   +2 more
doaj   +1 more source

Neutrophil Gelatinase-Associated Lipocalin Levels in Early and Late Onset Preeclampsia

Gynecology Obstetrics & Reproductive Medicine, 2020
Objective: To evaluate the serum neutrophil gelatinase-associated lipocalin levels in pregnant women with and without preeclampsia, early-onset preeclampsia and late-onset preeclampsia, preeclampsia with and without severe features, and investigate the ...
Onur Guralp, Nevin Tuten, Mahmut Oncul, Serdar A Acikgoz, Hakan Ekmekci, Abdullah Tuten   +5 more
doaj   +1 more source

Using urinary neutrophile gelatinase-associated lipocalin for prognosticate renal dysfunction in children with familial Mediterranean fever the study design: a pilot study

Advances in Rheumatology, 2021
Background The most important finding that affects the prognosis in Familial Mediterranean Fever is renal amyloidosis. The aim of the present study was to analyze neutrophil gelatinase-associated lipocalin levels in the urine, and to investigate whether ...
Sinem Can Oksay, Hasan Dursun, Sebnem Tekin Neijmann, Sami Hatipoglu   +3 more
doaj   +1 more source

Dynamics of Urinary Calprotectin after Renal Ischaemia. [PDF]

PLoS ONE, 2016
BACKGROUND:Urinary calprotectin has been identified as a promising biomarker for acute kidney injury. To date, however, the time-dependent changes of this parameter during acute kidney injury remain elusive.
Jan Ebbing, Felix S Seibert, Nikolaos Pagonas, Frederic Bauer, Kurt Miller, Carsten Kempkensteffen, Karsten Günzel, Alexander Bachmann, Hans H Seifert, Cyrill A Rentsch, Peter Ardelt, Christian Wetterauer, Patrizia Amico, Nina Babel, Timm H Westhoff   +14 more
doaj   +1 more source

Diagnostic performance of plasma and urine neutrophil gelatinase-associated lipocalin, cystatin C, and creatinine for acute kidney injury in burn patients: A prospective cohort study. [PDF]

PLoS ONE, 2018
BACKGROUND:Diagnosing acute kidney injury quickly is imperative since it is known as an independent risk factor for mortality in burn patients. We evaluated the diagnostic power of creatinine, cystatin, serum and urine neutrophil gelatinase-associated ...
Youngmin Kim, Yong Suk Cho, Dohern Kym, Jaechul Yoon, Haejun Yim, Jun Hur, Wook Chun   +6 more
doaj   +1 more source